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Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

Autor: Friedman CE; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; Centre for Cardiac and Vascular Biology, The University of Queensland, Brisbane, QLD 4072, Australia., Nguyen Q; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Lukowski SW; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Helfer A; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; Centre for Cardiac and Vascular Biology, The University of Queensland, Brisbane, QLD 4072, Australia., Chiu HS; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; Centre for Cardiac and Vascular Biology, The University of Queensland, Brisbane, QLD 4072, Australia., Miklas J; Departments of Pathology, Biochemistry, Bioengineering and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, The University of Washington, Seattle, WA 98195, USA., Levy S; Departments of Pathology, Biochemistry, Bioengineering and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, The University of Washington, Seattle, WA 98195, USA., Suo S; Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China., Han JJ; Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China., Osteil P; Embryology Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Peng G; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China., Jing N; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, 100 Haike Road, Shanghai 201210, China., Baillie GJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Senabouth A; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Christ AN; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Bruxner TJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Murry CE; Departments of Pathology, Biochemistry, Bioengineering and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, The University of Washington, Seattle, WA 98195, USA., Wong ES; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Ding J; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Wang Y; Departments of Pathology, Biochemistry, Bioengineering and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, The University of Washington, Seattle, WA 98195, USA; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA 98195, USA., Hudson J; Queensland Institute for Medical Research, Brisbane, QLD 4006, Australia., Ruohola-Baker H; Departments of Pathology, Biochemistry, Bioengineering and Medicine/Cardiology, Institute for Stem Cell and Regenerative Medicine, The University of Washington, Seattle, WA 98195, USA., Bar-Joseph Z; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Tam PPL; Embryology Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia; School of Medical Sciences, Sydney Medical School, University of Sydney, NSW 2006, Australia., Powell JE; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute for Medical Research, Sydney, NSW 2010, Australia. Electronic address: j.powell@garvan.org.au., Palpant NJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; Centre for Cardiac and Vascular Biology, The University of Queensland, Brisbane, QLD 4072, Australia; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address: n.palpant@uq.edu.au.

Publikováno v: Cell stem cell [Cell Stem Cell] 2018 Oct 04; Vol. 23 (4), pp. 586-598.e8.

Hypermutation In Pancreatic Cancer.

Autor: Humphris JL; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Patch AM; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Nones K; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Bailey PJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom., Johns AL; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., McKay S; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Chang DK; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom., Miller DK; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Pajic M; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia., Kassahn KS; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; Genetic and Molecular Pathology, Adelaide, South Australia, Australia; School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Quinn MC; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Bruxner TJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Christ AN; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Harliwong I; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Idrisoglu S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Manning S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Nourse C; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia., Nourbakhsh E; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Stone A; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Wilson PJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Anderson M; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Fink JL; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Holmes O; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Kazakoff S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Leonard C; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Newell F; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Waddell N; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Wood S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mead RS; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; South Eastern Area Laboratory Services Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia; Sonic Genetics, Douglass Hanly Moir Pathology, New South Wales, Australia., Xu Q; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Wu J; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Pinese M; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Cowley MJ; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia., Jones MD; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom., Nagrial AM; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Chin VT; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Chantrill LA; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Macarthur Cancer Therapy Centre, Campbelltown Hospital, New South Wales, Australia., Mawson A; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Chou A; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Department of Anatomical Pathology, SydPath, St Vincent's Hospital, New South Wales, Australia., Scarlett CJ; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; School of Environmental and Life Sciences, University of Newcastle, Ourimbah, New South Wales, Australia., Pinho AV; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Rooman I; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Giry-Laterriere M; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Samra JS; Department of Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia., Kench JG; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia., Merrett ND; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; School of Medicine, Western Sydney University, Penrith, New South Wales, Australia., Toon CW; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., Epari K; Department of Surgery, Fiona Stanley Hospital, Murdoch, Washington., Nguyen NQ; Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia., Barbour A; Department of Surgery, Princess Alexandra Hospital, Woollongabba, Queensland, Australia., Zeps N; School of Surgery, University of Western Australia, Australia and St John of God Pathology, Subiaco, Washington., Jamieson NB; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom; Academic Unit of Surgery, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom., McKay CJ; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom., Carter CR; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom., Dickson EJ; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom., Graham JS; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom., Duthie F; Department of Pathology, Southern General Hospital, Greater Glasgow & Clyde National Health Service, Glasgow, United Kingdom., Oien K; Department of Pathology, Southern General Hospital, Greater Glasgow & Clyde National Health Service, Glasgow, United Kingdom., Hair J; Greater Glasgow and Clyde Bio-repository, Pathology Department, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Morton JP; Cancer Research UK Beatson Institute, Glasgow, United Kingdom; Institute for Cancer Science, University of Glasgow, Glasgow, United Kingdom., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, United Kingdom; Institute for Cancer Science, University of Glasgow, Glasgow, United Kingdom., Grützmann R; Universitätsklinikum Erlangen, Erlangen, Germany., Hruban RH; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Maitra A; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Iacobuzio-Donahue CA; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Schulick RD; Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Wolfgang CL; Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Morgan RA; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Lawlor RT; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Rusev B; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Corbo V; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Salvia R; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Cataldo I; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Tortora G; Department of Medicine, University and Hospital Trust of Verona, Verona, Italy., Tempero MA; Division of Hematology and Oncology, University of California, San Francisco, California., Hofmann O; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom., Eshleman JR; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland., Pilarsky C; Universitätsklinikum Erlangen, Department of Surgery, University of Erlangen-Nueremberg, Germany., Scarpa A; ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy., Musgrove EA; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia., Gill AJ; The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia., Pearson JV; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Grimmond SM; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; University of Melbourne Centre for Cancer Research, The University of Melbourne, Melbourne, Victoria, Australia., Waddell N; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. Electronic address: nic.waddell@qimrberghofer.edu.au., Biankin AV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address: andrew.biankin@glasgow.ac.uk.

Publikováno v: Gastroenterology [Gastroenterology] 2017 Jan; Vol. 152 (1), pp. 68-74.e2. Date of Electronic Publication: 2016 Nov 15.

Genomic analyses identify molecular subtypes of pancreatic cancer.

Autor: Bailey P; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Chang DK; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia.; Department of Surgery, Bankstown Hospital, Eldridge Road, Bankstown, Sydney, New South Wales 2200, Australia.; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, Liverpool, New South Wales 2170, Australia., Nones K; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Johns AL; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Patch AM; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Gingras MC; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.; Michael DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA., Miller DK; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Christ AN; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Bruxner TJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Quinn MC; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Nourse C; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Murtaugh LC; Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA., Harliwong I; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Idrisoglu S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Manning S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Nourbakhsh E; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Wani S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Fink L; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Holmes O; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Chin V; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Anderson MJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Kazakoff S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Leonard C; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Newell F; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Waddell N; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Wood S; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Xu Q; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Wilson PJ; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Cloonan N; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Kassahn KS; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; Genetic and Molecular Pathology, SA Pathology, Adelaide, South Australia 5000, Australia.; School of Biological Sciences, The University of Adelaide, Adelaide, South Australia 5000, Australia., Taylor D; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Quek K; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Robertson A; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia., Pantano L; Harvard Chan Bioinformatics Core, Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Mincarelli L; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Sanchez LN; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Evers L; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Wu J; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Pinese M; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Cowley MJ; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Jones MD; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Colvin EK; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Nagrial AM; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Humphrey ES; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Chantrill LA; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia.; Macarthur Cancer Therapy Centre, Campbelltown Hospital, New South Wales 2560, Australia., Mawson A; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Humphris J; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Chou A; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia.; Department of Pathology. 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Rubenstein Pancreatic Cancer Research Center and Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Wolfgang CL; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.; Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Morgan RA; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Lawlor RT; ARC-Net Applied Research on Cancer Centre, University and Hospital Trust of Verona, Verona 37134, Italy.; Department of Pathology and Diagnostics, University of Verona, Verona 37134, Italy., Corbo V; ARC-Net Applied Research on Cancer Centre, University and Hospital Trust of Verona, Verona 37134, Italy., Bassi C; Department of Surgery, Pancreas Institute, University and Hospital Trust of Verona, Verona 37134, Italy., Rusev B; ARC-Net Applied Research on Cancer Centre, University and Hospital Trust of Verona, Verona 37134, Italy., Capelli P; Department of Pathology and Diagnostics, University of Verona, Verona 37134, Italy., Salvia R; Department of Surgery, Pancreas Institute, University and Hospital Trust of Verona, Verona 37134, Italy., Tortora G; Department of Medical Oncology, Comprehensive Cancer Centre, University and Hospital Trust of Verona, Verona 37134, Italy., Mukhopadhyay D; Mayo Clinic, Rochester, Minnesota 55905, USA., Petersen GM; Mayo Clinic, Rochester, Minnesota 55905, USA., Munzy DM; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.; Michael DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA., Fisher WE; Elkins Pancreas Center, Baylor College of Medicine, One Baylor Plaza, MS226, Houston, Texas 77030-3411, USA., Karim SA; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Eshleman JR; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Hruban RH; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Pilarsky C; Department of Surgery, TU Dresden, Fetscherstr. 74, 01307 Dresden, Germany., Morton JP; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; Institute for Cancer Science, University of Glasgow, Glasgow G12 8QQ, UK., Scarpa A; ARC-Net Applied Research on Cancer Centre, University and Hospital Trust of Verona, Verona 37134, Italy.; Department of Pathology and Diagnostics, University of Verona, Verona 37134, Italy., Musgrove EA; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Bailey UM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK., Hofmann O; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; Harvard Chan Bioinformatics Core, Harvard T. 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Chan School of Public Health, Boston, Massachusetts 02115, USA., Sutherland RL; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia., Wheeler DA; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.; Michael DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA., Gill AJ; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia.; University of Sydney, Sydney, New South Wales 2006, Australia., Gibbs RA; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.; Michael DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA., Pearson JV; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Waddell N; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia., Biankin AV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia.; Department of Surgery, Bankstown Hospital, Eldridge Road, Bankstown, Sydney, New South Wales 2200, Australia.; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, Liverpool, New South Wales 2170, Australia.; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow G31 2ER, UK., Grimmond SM; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.; University of Melbourne, Parkville, Victoria 3010, Australia.

Publikováno v: Nature [Nature] 2016 Mar 03; Vol. 531 (7592), pp. 47-52. Date of Electronic Publication: 2016 Feb 24.

Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.

Autor: Saunus JM; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Quinn MC; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Patch AM; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Pearson JV; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Bailey PJ; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, UK., Nones K; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., McCart Reed AE; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Miller D; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia.; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Wilson PJ; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Al-Ejeh F; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Mariasegaram M; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Lau Q; Pathology Queensland, Gold Coast Hospital, Southport, Queensland, Australia., Withers T; Department of Neurosurgery, Gold Coast Hospital, Southport, Queensland, Australia., Jeffree RL; Kenneth G Jamieson Department of Neurosurgery, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia., Reid LE; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Da Silva L; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; University of Queensland School of Medicine, Herston, Queensland, Australia., Matsika A; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia., Niland CM; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Cummings MC; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; University of Queensland School of Medicine, Herston, Queensland, Australia.; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia., Bruxner TJ; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Christ AN; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Harliwong I; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Idrisoglu S; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Manning S; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Nourse C; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, UK., Nourbakhsh E; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Wani S; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Anderson MJ; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Fink JL; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Holmes O; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Kazakoff S; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Leonard C; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Newell F; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Taylor D; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Waddell N; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Wood S; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Xu Q; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Kassahn KS; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia.; Genetic and Molecular Pathology, SA Pathology, Women's and Children's Hospital, North Adelaide, South Australia, Australia.; School of Molecular and Biomedical Science, University of Adelaide, South Australia, Australia., Narayanan V; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Taib NA; Breast Unit, Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; University Malaya Cancer Research Institute, University of Malaya, Kuala Lumpur, Malaysia., Teo SH; University Malaya Cancer Research Institute, University of Malaya, Kuala Lumpur, Malaysia.; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Selangor, Malaysia., Chow YP; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Selangor, Malaysia., kConFab; Peter MacCallum Cancer Centre, University of Melbourne, Victoria, Australia., Jat PS; Department of Neurodegenerative Disease and MRC Prion Unit, UCL Institute of Neurology, London, UK., Brandner S; Division of Neuropathology and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Flanagan AM; Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, UK.; University College London Cancer Institute, London, UK., Khanna KK; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Chenevix-Trench G; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Grimmond SM; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia.; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, UK., Simpson PT; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; University of Queensland School of Medicine, Herston, Queensland, Australia., Waddell N; QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.; Queensland Centre for Medical Genomics, IMB, University of Queensland, St Lucia, Queensland, Australia., Lakhani SR; University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia.; University of Queensland School of Medicine, Herston, Queensland, Australia.; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

Publikováno v: The Journal of pathology [J Pathol] 2015 Nov; Vol. 237 (3), pp. 363-78. Date of Electronic Publication: 2015 Aug 19.