Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Brusatol"'
Autor:
Juan Zhang, Hongxi Xu, Yulin Wu, William Chi Shing Cho, Yang Li, Peiyao Ren, Yanfang Xian, Zhixiu Lin
Publikováno v:
Acta Materia Medica, Vol 3, Iss 3, Pp 312-327 (2024)
Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC). Nrf2, a transcription factor responsive to oxidative stress, has been implicated as a key contributor to chemor
Externí odkaz:
https://doaj.org/article/f730db7dae1040a6882785f4c8debe74
Publikováno v:
环境与职业医学, Vol 41, Iss 5, Pp 539-545 (2024)
BackgroundSilicosis is a diffuse fibrosis of the lungs caused by long-term inhalation of free silicon dioxide (SiO2). It has a complex pathogenesis and lacks effective treatment. Brusatol (Bru) has a variety of biological activities, and its role in
Externí odkaz:
https://doaj.org/article/e4f09a832a124d6897fb14a6ddfb1c21
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116977- (2024)
Background: Pancreatic cancer (PanCa), ranked as the 4th leading cause of cancer-related death worldwide, exhibits an dismal 5-year survival rate of less than 5 %. Chronic pancreatitis (CP) is a known major risk factor for PanCa. Brusatol (BRT) posse
Externí odkaz:
https://doaj.org/article/eddf9803d21749eeb5047a5767815a7f
Autor:
Xu Zhu, Nannan Huang, Yao Ji, Xinling Sheng, Juanjuan Huo, Yuan Zhu, Menghuan Huang, Wei He, Junting Ma
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115567- (2023)
Brusatol (Bru), a bioactive compound found in Brucea sumatrana, exerts antitumour effects on several malignancies. However, the role and molecular mechanism of Bru in squamous cell carcinoma of the oesophagus (ESCC) remain unclear. Here, we found tha
Externí odkaz:
https://doaj.org/article/e45e85f872bf454a99f020a197443be7
Autor:
Hunter R. Ford, Massimo Bionaz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4264 (2024)
Changes during the production cycle of dairy cattle can leave these animals susceptible to oxidative stress and reduced antioxidant health. In particular, the periparturient period, when dairy cows must rapidly adapt to the sudden metabolic demands o
Externí odkaz:
https://doaj.org/article/b0697b11a9aa4434a7b98b764d17fbbd
Autor:
Lu-Ming Yang, Wen-Min Zhou, Qiao-Ru Guo, Xin-Yue Fan, Dong-Yu Huang, Xiao-Fei Sun, Jie Yuan, Hua Yu, Hu-Biao Chen, Jian-Ye Zhang
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 9, Iss 4, Pp 454-460 (2023)
Objective: The purpose of this study was to investigate the inhibitory effect of brusatol, a nigakilactone extracted from Brucea javanica, on lung cancer for development of therapeutic drugs. We explored the effects of brusatol on the proliferation,
Externí odkaz:
https://doaj.org/article/f0950290657e490b8ec017a520c74901
Autor:
Ziming Guo, Na Li, Yuankuan Jiang, Li Zhang, Lidong Tong, Yipin Wang, Peng Lv, Xiaojie Li, Chuanchun Han, Jingrong Lin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114650- (2023)
Brusatol (Bru), a Chinese medicine Brucea javanica extract, has a variety of antitumour effects. However, its role and underlying mechanism in melanoma have not been fully elucidated. In this study, we found that brusatol inhibited melanoma cell prol
Externí odkaz:
https://doaj.org/article/48c2ec6e1a77497695842f8199a8fa57
Autor:
Tayo Alex Adekiya, Madison Moore, Michael Thomas, Gabriel Lake, Tamaro Hudson, Simeon K. Adesina
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 114 (2024)
Challenges to docetaxel use in prostate cancer treatment include several resistance mechanisms as well as toxicity. To overcome these challenges and to improve the therapeutic efficacy in heterogeneous prostate cancer, the use of multiple agents that
Externí odkaz:
https://doaj.org/article/26bf546b03d94f69b18d615cf71e72fe
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.