Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Bruno Weber"'
Autor:
Lukas Glandorf, Bastian Wittmann, Jeanne Droux, Chaim Glück, Bruno Weber, Susanne Wegener, Mohamad El Amki, Rainer Leitgeb, Bjoern Menze, Daniel Razansky
Publikováno v:
Light: Science & Applications, Vol 13, Iss 1, Pp 1-14 (2024)
Abstract Understanding the morphology and function of large-scale cerebrovascular networks is crucial for studying brain health and disease. However, reconciling the demands for imaging on a broad scale with the precision of high-resolution volumetri
Externí odkaz:
https://doaj.org/article/aaaa1c3f9cf743a79d273831bc2539eb
Autor:
Marie A. Labouesse, Maria Wilhelm, Zacharoula Kagiampaki, Andrew G. Yee, Raphaelle Denis, Masaya Harada, Andrea Gresch, Alina-Măriuca Marinescu, Kanako Otomo, Sebastiano Curreli, Laia Serratosa Capdevila, Xuehan Zhou, Reto B. Cola, Luca Ravotto, Chaim Glück, Stanislav Cherepanov, Bruno Weber, Xin Zhou, Jason Katner, Kjell A. Svensson, Tommaso Fellin, Louis-Eric Trudeau, Christopher P. Ford, Yaroslav Sych, Tommaso Patriarchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Genetically-encoded dopamine (DA) sensors enable high-resolution imaging of DA release, but their ability to detect a wide range of extracellular DA levels, especially tonic versus phasic DA release, is limited by their intrinsic affinity. H
Externí odkaz:
https://doaj.org/article/edad0bcf8205400a8af1560d0567e9ed
Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release
Autor:
Xuehan Zhou, Carrie Stine, Patricia Oliveira Prada, Debora Fusca, Kevin Assoumou, Jan Dernic, Musadiq A. Bhat, Ananya S. Achanta, Joseph C. Johnson, Amanda Loren Pasqualini, Sanjana Jadhav, Corinna A. Bauder, Lukas Steuernagel, Luca Ravotto, Dietmar Benke, Bruno Weber, Azra Suko, Richard D. Palmiter, Miriam Stoeber, Peter Kloppenburg, Jens C. Brüning, Michael R. Bruchas, Tommaso Patriarchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Nociceptin/orphanin-FQ (N/OFQ) is a recently appreciated critical opioid peptide with key regulatory functions in several central behavioral processes including motivation, stress, feeding, and sleep. The functional relevance of N/OFQ action
Externí odkaz:
https://doaj.org/article/85f93020cae0443ca2de0481924bf37c
Autor:
Quanyu Zhou, Chaim Glück, Lin Tang, Lukas Glandorf, Jeanne Droux, Mohamad El Amki, Susanne Wegener, Bruno Weber, Daniel Razansky, Zhenyue Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Large-scale imaging of brain activity with high spatio-temporal resolution is crucial for advancing our understanding of brain function. The existing neuroimaging techniques are largely limited by restricted field of view, slow imaging speed
Externí odkaz:
https://doaj.org/article/6bfaf5d2a6094868874a939422683f9a
Autor:
Yuan-Chen Tsai, Mohammad Hleihil, Kanako Otomo, Andrin Abegg, Anna Cavaccini, Patrizia Panzanelli, Teresa Cramer, Kim David Ferrari, Matthew J. P. Barrett, Giovanna Bosshard, Theofanis Karayannis, Bruno Weber, Shiva K. Tyagarajan, Jillian L. Stobart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Gephyrin is the main scaffolding protein at inhibitory postsynaptic sites, and its clusters are the signaling hubs where several molecular pathways converge. Post-translational modifications (PTMs) of gephyrin alter GABAA receptor clustering
Externí odkaz:
https://doaj.org/article/61f06bd1f1de40d1b7c391b161388674
Autor:
Noushin Ahmadpour, Meher Kantroo, Michael J. Stobart, Jessica Meza-Resillas, Shahin Shabanipour, Jesus Parra-Nuñez, Tetiana Salamovska, Anna Muzaleva, Finnegan O’Hara, Dustin Erickson, Bruno Di Gaetano, Sofia Carrion-Falgarona, Bruno Weber, Alana Lamont, Natalie E. Lavine, Tiina M. Kauppinen, Michael F. Jackson, Jillian L. Stobart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown ap
Externí odkaz:
https://doaj.org/article/a8ce933929184bcfa3f5b6c95d1aad63
Autor:
Pascal Bebié, Werner Lustermann, Jan Debus, Christian Ritzer, Günther Dissertori, Bruno Weber
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-20 (2023)
Abstract Background Small Animal Fast Insert for MRI detector I (SAFIR-I) is a novel Positron Emission Tomography insert for a $$7\,\hbox {T}$$ 7 T Bruker BioSpec 70/30 Ultra Shield Refrigerated Magnetic Resonance Imaging (MRI) system. It facilitates
Externí odkaz:
https://doaj.org/article/ee0e076b1a57477db1de1c813428c501
Autor:
Alexia Del Campo Fonseca, Chaim Glück, Jeanne Droux, Yann Ferry, Carole Frei, Susanne Wegener, Bruno Weber, Mohamad El Amki, Daniel Ahmed
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The intricate and delicate anatomy of the brain poses significant challenges for the treatment of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in hard-to-reach brain regions remains an urgent medical need
Externí odkaz:
https://doaj.org/article/511cb0bee38a42749fe0db595e88ca70
Autor:
Xosé Luís Deán-Ben, Justine Robin, Daniil Nozdriukhin, Ruiqing Ni, Jim Zhao, Chaim Glück, Jeanne Droux, Juan Sendón-Lago, Zhenyue Chen, Quanyu Zhou, Bruno Weber, Susanne Wegener, Anxo Vidal, Michael Arand, Mohamad El Amki, Daniel Razansky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Super-resolution optoacoustic imaging of microvascular structures deep in mammalian tissues has so far been impeded by strong absorption from densely-packed red blood cells. Here we devised 5 µm biocompatible dichloromethane-based microdrop
Externí odkaz:
https://doaj.org/article/5017b886ff8f4b87b739c11b399deb6f
Autor:
Vyara Todorova, Mia Fee Stauffacher, Luca Ravotto, Sarah Nötzli, Duygu Karademir, Lynn J. A. Ebner, Cornelia Imsand, Luca Merolla, Stefanie M. Hauck, Marijana Samardzija, Aiman S. Saab, L. Felipe Barros, Bruno Weber, Christian Grimm
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Major retinal degenerative diseases, including age-related macular degeneration, diabetic retinopathy and retinal detachment, are associated with a local decrease in oxygen availability causing the formation of hypoxic areas affec
Externí odkaz:
https://doaj.org/article/5ce307904c724ad3afa5932f84399175