Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Bruno Stuhlmüller"'
Publikováno v:
J, Vol 3, Iss 2, Pp 181-194 (2020)
Rheumatoid arthritis (RA) is a chronic inflammatory and destructive joint disease characterized by overexpression of pro-inflammatory/pro-destructive mediators, whose regulation has been the focus of our previous studies. Since the expression of thes
Externí odkaz:
https://doaj.org/article/524285cbc3e24d218d9da7ad036a57d3
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Idiopathic inflammatory myopathies represent still a diagnostic and therapeutic challenge in different disciplines including neurology, rheumatology, and dermatology. In recent years, the spectrum of idiopathic inflammatory myopathies has been signif
Externí odkaz:
https://doaj.org/article/e6788e7edd56487c9c0ff53a92e05ca8
Autor:
René Huber, Sandra Augsten, Holger Kirsten, Roland Zell, Axel Stelzner, Hansjörg Thude, Thorsten Eidner, Bruno Stuhlmüller, Peter Ahnert, Raimund W. Kinne
Publikováno v:
Life, Vol 11, Iss 1, p 5 (2020)
In rheumatoid arthritis (RA), the expression of many pro-destructive/pro-inflammatory proteins depends on the transcription factor AP-1. Therefore, our aim was to analyze the presence and functional relevance of mutations in the coding regions of the
Externí odkaz:
https://doaj.org/article/c8123164d9364538a66d3a2d03c9ba8a
Autor:
Michalsen, Thomas Häupl, Till Sörensen, Biljana Smiljanovic, Marine Darcy, Justus Scheder-Bieschin, Nico Steckhan, Anika M. Hartmann, Daniela A. Koppold, Bruno Stuhlmüller, Karl Skriner, Barbara M. Walewska, Berthold Hoppe, Marc Bonin, Gerd R. Burmester, Pascal Schendel, Eugen Feist, Karsten Liere, Martin Meixner, Christian Kessler, Andreas Grützkau, Andreas
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 13; Pages: 4359
Rheumatoid arthritis (RA) synovitis is dominated by monocytes/macrophages with inflammatory patterns resembling microbial stimulation. In search of triggers, we reduced the intestinal microbiome in 20 RA patients (open label study DRKS00014097) by bo
Publikováno v:
Aktuelle Rheumatologie. 46:343-360
ZusammenfassungDie idiopathischen inflammatorischen Myopathien (IIM) sind eine Gruppe entzündlicher Muskelerkrankungen für deren Diagnosestellung, Verlaufsbeurteilung, Prognoseabschätzung und Risikostratifizierung Biomarker eine jeweils essentiell
Autor:
Sandra Hermann, Marc Bonin, Bruno Stuhlmüller, Anne Claussnitzer, Biljana Smiljanovic, Karlfried Aupperle, Sarah Ohrndorf, Marina Backhaus, Till Sörensen, Joachim R. Grün, Andreas Radbruch, Thomas Häupl, Andreas Grützkau, Pascal Schendel, Gerd R Burmester, Thomas Vogl
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Advances in microbiome research suggest involvement in chronic inflammatory diseases such as rheumatoid arthritis (RA). Searching for initial trigger(s) in RA, we compared transcriptome profiles of highly inflamed RA synovial tissue (RA-ST) and osteo
Autor:
Gerd-Rüdiger Burmester, Bruno Stuhlmüller, D Abdirama, Elise Siegert, Andreas Radbruch, Philipp Enghard, Eugen Feist, Tobias Alexander, Martina Bertolo, Dörte Huscher, Caroline von Spee-Mayer, A. Rose, Jens Y Humrich, Gabriela Riemekasten, Birgit Sawitzki, Falk Hiepe
Publikováno v:
The Lancet Rheumatology. 1:e44-e54
Summary Background An acquired deficiency of interleukin-2 (IL-2) and related defects in regulatory T cell homeostasis are thought to play a crucial role in the pathogenesis of systemic lupus erythematosus. We hypothesised that reconstitution of regu
Autor:
Ilka Liebold, Andreas Grützkau, Anika Göckeritz, Velia Gerl, Randall Lindquist, Eugen Feist, Michael Zänker, Thomas Häupl, Denis Poddubnyy, Jan Zernicke, Biljana Smiljanovic, Tobias Alexander, Gerd R Burmester, Steffen Gay, Bruno Stuhlmüller
Objective Epigenetic modifications are dynamic and influence cellular disease activity. The aim of this study was to investigate global DNA methylation in peripheral blood mononuclear cells (PBMCs) of RA patients to clarify whether global DNA methyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e365ea75f769fb420396dc2dcea6f8
https://doi.org/10.5167/uzh-192393
https://doi.org/10.5167/uzh-192393
Autor:
Raimund W. Kinne, Thorsten Eidner, Bruno Stuhlmüller, Holger Kirsten, Sandra Augsten, Roland Zell, Peter Ahnert, Hansjörg Thude, René Huber, Axel Stelzner
Publikováno v:
Life
Volume 11
Issue 1
Life, Vol 11, Iss 5, p 5 (2021)
Volume 11
Issue 1
Life, Vol 11, Iss 5, p 5 (2021)
In rheumatoid arthritis (RA), the expression of many pro-destructive/pro-inflammatory proteins depends on the transcription factor AP-1. Therefore, our aim was to analyze the presence and functional relevance of mutations in the coding regions of the
Autor:
Ulrich Mansmann, Philipp Sewerin, Berthold Hoppe, Karl Skriner, Bruno Stuhlmüller, G.-R. Burmester, Hendrik Schulze-Koops, Thomas Häupl, Sarah Ohrndorf, Denis Poddubnyy, Alla Skapenko, Harald Burkhardt
Publikováno v:
Zeitschrift für Rheumatologie. 77:16-23
Rheumatische Erkrankungen gehören zu den häufigsten chronisch entzündlichen Krankheiten. Neben ausgeprägter Schmerzhaftigkeit und progredienter Gelenkzerstörung reduzieren die rheumatoide Arthritis (RA), die Spondyloarthritiden (SpA) und die Pso