Zobrazeno 1 - 10
of 634
pro vyhledávání: '"Bruno Reichart"'
Publikováno v:
Transplant International, Vol 37 (2024)
Xenotransplantation of porcine hearts has become a promising alternative to human allotransplantation, where organ demand still greatly surpasses organ availability. Before entering the clinic, however, feasibility of cardiac xenotransplantation need
Externí odkaz:
https://doaj.org/article/ac08bcf1733743ecac24331bffb7acbd
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Elisabeth Neumann, Julia Radan, Maren Mokelke, Ines Buttgereit, Maria Leuschen, Felicia Wall, Sebastian Michel, Reinhard Ellgass, Stig Steen, Audrius Paskevicius, Andreas Lange, Barbara Kessler, Elisabeth Kemter, Nikolai Klymiuk, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Jonathan M. Burgmann, Constança Figueiredo, Anastasia Milusev, Valentina Zollet, Neda Salimi-Afjani, Alain Despont, Robert Rieben, Stephan Ledderose, Christoph Walz, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Uli Binder, Michaela Gebauer, Arne Skerra, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1927 (2024)
The blockade of the CD40/CD40L immune checkpoint is considered essential for cardiac xenotransplantation. However, it is still unclear which single antibody directed against CD40 or CD40L (CD154), or which combination of antibodies, is better at prev
Externí odkaz:
https://doaj.org/article/8c1badf713bc4998ad88ccdb88bead35
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Maria Leuschen, Felicia Wall, Julia Radan, Elisabeth Neumann, Maren Mokelke, Ines Buttgereit, Sebastian Michel, Reinhard Ellgass, Katja Gieseke, Stig Steen, Audrius Paskevicius, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Martin B. Müller, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1336 (2024)
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation. Despite these achievements, acute vascular rejection still presents a challenge for long-t
Externí odkaz:
https://doaj.org/article/c841e0d47f65460a97bd17080a2ace3d
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/157e044ef2334e2eade288edbfc84648
Autor:
Hina Jhelum, Martin Bender, Bruno Reichart, Maren Mokelke, Julia Radan, Elisabeth Neumann, Ludwig Krabben, Jan-Michael Abicht, Benedikt Kaufer, Matthias Längin, Joachim Denner
Publikováno v:
Viruses, Vol 15, Iss 7, p 1618 (2023)
Xenotransplantation, like allotransplantation, is usually associated with microchimerism, i.e., the presence of cells from the donor in the recipient. Microchimerism was reported in first xenotransplantation trials in humans, as well as in most precl
Externí odkaz:
https://doaj.org/article/a68569324e2146edaafc5ad5c5ed0d78
Autor:
Luise Krüger, Matthias Längin, Bruno Reichart, Uwe Fiebig, Yannick Kristiansen, Carolin Prinz, Barbara Kessler, Stefanie Egerer, Eckhard Wolf, Jan-Michael Abicht, Joachim Denner
Publikováno v:
Viruses, Vol 11, Iss 7, p 650 (2019)
Porcine circovirus 3 (PCV3) is a newly described member of the virus family Circoviridae. PCV3 is highly distributed among pigs and wild boars worldwide. A sudden introduction of PCV3 was recently observed in a herd of triple genetically modified pig
Externí odkaz:
https://doaj.org/article/36f7a17e483b42f6b1f2ca0548ca298a
Autor:
Eike Kleinert, Martin C. Langenmayer, Bruno Reichart, Jana Kindermann, Barbara Griemert, Andreas Blutke, Kerstin Troidl, Tanja Mayr, Tobias Grantzow, Fatih Noyan, Jan‐Michael Abicht, Silvia Fischer, Klaus T. Preissner, Ruediger Wanke, Elisabeth Deindl, Sonja Guethoff
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)
BackgroundCell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti‐inflammatory and cardioprot
Externí odkaz:
https://doaj.org/article/b04da19692014e569902ca00f3570714
Autor:
Bassil Akra, Erich Wintermantel, Christian Hagl, Bruno Reichart, Trixi Hollweck, Stefan Pfeifer, Fabian König
Publikováno v:
Journal of Functional Biomaterials, Vol 3, Iss 3, Pp 480-496 (2012)
Heart valve disease (HVD) is a globally increasing problem and accounts for thousands of deaths yearly. Currently end-stage HVD can only be treated by total valve replacement, however with major drawbacks. To overcome the limitations of conventional
Externí odkaz:
https://doaj.org/article/574fe997b4a14a3dae52f4a7de27bd23
Autor:
Uwe Fiebig, Jan-Michael Abicht, Tanja Mayr, Matthias Längin, Andrea Bähr, Sonja Guethoff, Almuth Falkenau, Eckhard Wolf, Bruno Reichart, Tomoyuki Shibahara, Joachim Denner
Publikováno v:
Viruses, Vol 10, Iss 2, p 66 (2018)
The porcine cytomegalovirus (PCMV) is a herpesvirus that may pose a risk for xenotransplantation using pig cells, tissues, or organs. Here, three orthotopic pig heart transplantations into baboons were studied. To detect PCMV, a real-time PCR and a W
Externí odkaz:
https://doaj.org/article/ecd547372cf44f27908b2578ad253e87
Autor:
Bruno Reichart, David K C Cooper, Matthias Längin, Ralf R Tönjes, Richard N Pierson, Eckhard Wolf
Publikováno v:
Cardiovascular Research. 118:3499-3516
For many patients with terminal/advanced cardiac failure, heart transplantation is the most effective, durable treatment option, and offers the best prospects for a high quality of life. The number of potentially life-saving donated human organs is f