Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Bruno Pillot"'
Autor:
Fabrice Gonnot, Laura Boulogne, Camille Brun, Maya Dia, Yves Gouriou, Gabriel Bidaux, Christophe Chouabe, Claire Crola Da Silva, Sylvie Ducreux, Bruno Pillot, Andrea Kaczmarczyk, Christelle Leon, Stephanie Chanon, Coralie Perret, Franck Sciandra, Tanushri Dargar, Vincent Gache, Fadi Farhat, Laurent Sebbag, Thomas Bochaton, Helene Thibault, Michel Ovize, Melanie Paillard, Ludovic Gomez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Despite advances in cardioprotection, new therapeutic strategies capable of preventing ischemia-reperfusion injury of patients are still needed. Here, we discover that sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA2) phosphorylation a
Externí odkaz:
https://doaj.org/article/053c384d17c44370a498964ce4cdcaa1
Autor:
Maya Dia, Alexandre Paccalet, Bruno Pillot, Christelle Leon, Michel Ovize, Claire Crola Da Silva, Thomas Bochaton, Melanie Paillard
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
In front of the failure to translate from bench to bedside cardioprotective drugs against myocardial ischemia-reperfusion, research scientists are currently revising their animal models. Owing to its growing incidence nowadays, type 2 diabetes (T2D)
Externí odkaz:
https://doaj.org/article/3343fc2552254e8f9749198188c137b4
Autor:
Laura Bouche, Rima Kamel, Sophie Tamareille, Gabriel Garcia, Camille Villedieu, Bruno Pillot, Naïg Gueguen, Ahmad Chehaitly, Juan Manuel Chao de la Barca, Justine Beaumont, Delphine Baetz, Michel Ovize, Hiromi Sesaki, Daniel Henrion, Pascal Reynier, Guy Lenaers, Fabrice Prunier, Delphine Mirebeau-Prunier
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248554 (2021)
Mitochondrial dynamics is a possible modulator of myocardial ischemia/reperfusion injuries (IRI). We previously reported that mice partially deficient in the fusion protein OPA1 exhibited higher IRI. Therefore, we investigated whether deficiency in t
Externí odkaz:
https://doaj.org/article/9ab091e55732459fa744e56ae7434f81
Autor:
Sally Badawi, Alexandre Paccalet, Zeina Harhous, Bruno Pillot, Lionel Augeul, Fabien Van Coppenolle, Joel Lachuer, Mazen Kurdi, Claire Crola Da Silva, Michel Ovize, Gabriel Bidaux
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
BackgroundIschemic heart diseases are a major cause of death worldwide. Different animal models, including cardiac surgery, have been developed over time. Unfortunately, the surgery models have been reported to trigger an important inflammatory respo
Externí odkaz:
https://doaj.org/article/6c3122af90444feb9a8395bf73704b54
Autor:
Ribal Al-Mawla, Mallory Ducrozet, Nolwenn Tessier, Lucille Païta, Bruno Pillot, Yves Gouriou, Camille Villedieu, Zeina Harhous, Alexandre Paccalet, Claire Crola Da Silva, Michel Ovize, Gabriel Bidaux, Sylvie Ducreux, Fabien Van Coppenolle
Publikováno v:
Cells, Vol 9, Iss 5, p 1319 (2020)
During myocardial infarction, dysregulation of Ca2+ homeostasis between the reticulum, mitochondria, and cytosol occurs in cardiomyocytes and leads to cell death. Ca2+ leak channels are thought to be key regulators of the reticular Ca2+ homeostasis a
Externí odkaz:
https://doaj.org/article/b99c6f2ded2b401e857ccfaa43f51137
Autor:
Sandrine Lemoine, Bruno Pillot, Lionel Augeul, Maud Rabeyrin, Annie Varennes, Gabrielle Normand, Delphine Baetz, Michel Ovize, Laurent Juillard
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182358 (2017)
There is experimental evidence that lethal ischemia-reperfusion injury (IRI) is largely due to mitochondrial permeability transition pore (mPTP) opening, which can be prevented by cyclosporine A (CsA). The aim of our study is to show that a higher do
Externí odkaz:
https://doaj.org/article/ec8329232df645fbb8d003c3765636cc
Autor:
Bruno Pillot, Céline Duraffourd, Martine Bégeot, Aurélie Joly, Serge Luquet, Isabelle Houberdon, Danielle Naville, Michèle Vigier, Amandine Gautier-Stein, Christophe Magnan, Gilles Mithieux
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19107 (2011)
The hypothalamic melanocortin system--the melanocortin receptor of type 4 (MC4R) and its ligands: α-melanin-stimulating hormone (α-MSH, agonist, inducing hypophagia), and agouti-related protein (AgRP, antagonist, inducing hyperphagia)--is considere
Externí odkaz:
https://doaj.org/article/225e60bfed854806bd5c4c8cbc1efa52
Autor:
Nicolas Marsollier, Nadim Kassis, Karima Mezghenna, Maud Soty, Xavier Fioramonti, Amélie Lacombe, Aurélie Joly, Bruno Pillot, Carine Zitoun, José Vilar, Gilles Mithieux, René Gross, Anne-Dominique Lajoix, Vanessa Routh, Christophe Magnan, Céline Cruciani-Guglielmacci
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6649 (2009)
Deregulation of hypothalamic fatty acid sensing lead to hepatic insulin-resistance which may partly contribute to further impairment of glucose homeostasis.We investigated here whether hypothalamic nitric oxide (NO) could mediate deleterious peripher
Externí odkaz:
https://doaj.org/article/e8b413eddeff4419be13831276fce815
A novel fluorescence imaging of myoglobin redox STATE reveals early reperfusion-injury in myocardium
Autor:
Sally Badawi, Clémence Leboullenger, Matthieu Chourout, Yves Gouriou, Alexandre Paccalet, Chris Berd, Bruno Pillot, Lionel Augeul, Radu Bolbos, Antonino Bongiovani, Michel Ovize, Nathan Mewton, Thomas Bochaton, Meryem Tardivel, Emmanuelle Canet-Soulas, Claire Corla da Silva, Gabriel Bidaux
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:68-69
Autor:
Zeina Harhous, Alexandre Paccalet, Sally Badawi, Michel Ovize, Lionel Augeul, Bruno Pillot, Ludovic Gomez, Thomas Bochaton, Nathan Mewton, Claire Corla da Silva, Mazen Kurdi, Gabriel Bidaux
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:13-14