Bixin Combined with Metformin Ameliorates Insulin Resistance and Antioxidant Defenses in Obese Mice

Autor: Camila Graça Pinheiro, Bruno Pereira Motta, Juliana Oriel Oliveira, Felipe Nunes Cardoso, Ingrid Delbone Figueiredo, Rachel Temperani Amaral Machado, Patrícia Bento da Silva, Marlus Chorilli, Iguatemy Lourenço Brunetti, Amanda Martins Baviera

Publikováno v: Pharmaceuticals, Vol 17, Iss 9, p 1202 (2024)

Bixin (C25H30O4; 394.51 g/mol) is the main apocarotenoid found in annatto seeds. It has a 25-carbon open chain structure with a methyl ester group and carboxylic acid. Bixin increases the expression of antioxidant enzymes, which may be interesting fo

Externí odkaz: https://doaj.org/article/c123b43cb5a54b02953a62bd2d284738

Combined Effects of Lycopene and Metformin on Decreasing Oxidative Stress by Triggering Endogenous Antioxidant Defenses in Diet-Induced Obese Mice

Autor: Bruno Pereira Motta, Camila Graça Pinheiro, Ingrid Delbone Figueiredo, Felipe Nunes Cardoso, Juliana Oriel Oliveira, Rachel Temperani Amaral Machado, Patrícia Bento da Silva, Marlus Chorilli, Iguatemy Lourenço Brunetti, Amanda Martins Baviera

Publikováno v: Molecules, Vol 27, Iss 23, p 8503 (2022)

Since lycopene has antioxidant activity, its combination with metformin may be useful to contrast diabetic complications related to oxidative stress. This study aimed to investigate the effects of metformin combined with lycopene on high-fat diet (HF

Externí odkaz: https://doaj.org/article/06b6f1c26a664222a3713dfb8506e612

Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity

Autor: Wilquer Castro Laurindo, Bruno Pereira Motta, Igor Muccilo Prokopczyk, Jean Leandro dos Santos, Flávio Henrique-Silva, Danyelle Toyama, Leandro da Costa Clementino, Guilherme Felipe dos Santos Fernandes, Amanda Martins Baviera, Marcia A. S. Graminha

Publikováno v: PLoS ONE
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 16, Iss 11, p e0259008 (2021)

Made available in DSpace on 2022-05-01T10:03:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2e1dad14f0a2f49ede2d2b52cb6476
http://europepmc.org/articles/PMC8559926

New compounds of Siolmatra brasiliensis and inhibition of in vitro protein glycation damage

Autor: Carlos Henrique Corrêa dos Santos, Paulo Teixeira de Sousa-Junior, Mario Geraldo de Carvalho, Ludger A. Wessjohann, Bruno Pereira Motta, Amanda Martins Baviera, Virgínia Claudia da Silva, Anderson Kiyoshi Kaga, Rosane Nora Castro, Tassiana Cristina Talpo

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2019-10-06T16:12:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-03-01 Twenty compounds were isolated from the hydroethanolic extract of the stems of Siolmatra brasiliensis, five flavonoids, two lignans, one gluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98f0907bf7b74e58c333c542c36d374
https://doi.org/10.1016/j.fitote.2018.12.023

Rutin inhibits the in vitro formation of advanced glycation products and protein oxidation more efficiently than quercetin

Autor: Anderson Kiyoshi Kaga, Tayra Ferreira Oliveira Lima, Karen Ramalho Palermo, Amanda Martins Baviera, Danyelle Trevisan Macedo Dias, Bruno Pereira Motta, Iguatemy Lourenço Brunetti

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 42, Pp 1-13 (2021)

Made available in DSpace on 2022-04-29T08:31:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Introduction: The exacerbated generation of advanced glycation end pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7575906e3d5ab3ce2731d8c8a17f81