Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Bruno Paiva"'
Autor:
Alice Leroux, Micaela Roque, Elina Casas, Jacques Leng, Christelle Guibert, Beatrice L’Azou, Hugo Oliveira, Joëlle Amédée, Bruno Paiva dos Santos
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-15 (2024)
Abstract Increasing evidences demonstrate the role of sensory innervation in bone metabolism, remodeling and repair, however neurovascular coupling in bone is rarely studied. Using microfluidic devices as an indirect co-culture model to mimic in vitr
Externí odkaz:
https://doaj.org/article/4b63a37cfd354668ad8ab92978ca7b14
Autor:
Esperanza Martín-Sánchez, Luis-Esteban Tamariz-Amador, Camila Guerrero, Anastasiia Zherniakova, Aintzane Zabaleta, Catarina Maia, Laura Blanco, Diego Alignani, Maria-Antonia Fortuño, Carlos Grande, Andrea Manubens, Jose-Maria Arguiñano, Clara Gomez, Ernesto Perez-Persona, Iñigo Olazabal, Itziar Oiartzabal, Carlos Panizo, Felipe Prosper, Jesus F. San-Miguel, Paula Rodriguez-Otero, Bruno Paiva, the Asociación Vasco-Navarra de Hematología y Hemoterapia (ASOVASNA) cooperative group
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Infection is the leading cause of death in multiple myeloma (MM). However, the cellular composition associated with immune dysfunction is not defined. We analyzed immune profiles in the peripheral blood of patients with MM (n = 28) and B-cel
Externí odkaz:
https://doaj.org/article/d290946f1de348f38a26beba2fae6800
Autor:
Edurne San José-Enériz, Naroa Gimenez-Camino, Obdulia Rabal, Leire Garate, Estibaliz Miranda, Nahia Gómez-Echarte, Fernando García, Stella Charalampopoulou, Elena Sáez, Amaia Vilas-Zornoza, Patxi San Martín-Uriz, Luis V. Valcárcel, Naroa Barrena, Diego Alignani, Luis Esteban Tamariz-Amador, Ana Pérez-Ruiz, Sebastian Hilscher, Mike Schutkowski, Ana Alfonso-Pierola, Nicolás Martinez-Calle, María José Larrayoz, Bruno Paiva, María José Calasanz, Javier Muñoz, Marta Isasa, José Ignacio Martin-Subero, Antonio Pineda-Lucena, Julen Oyarzabal, Xabier Agirre, Felipe Prósper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Despite the development of novel therapies for acute myeloid leukemia, outcomes remain poor for most patients, and therapeutic improvements are an urgent unmet need. Although treatment regimens promoting differentiation have succeeded in the
Externí odkaz:
https://doaj.org/article/c19f4277205c445384d53303bce19ff2
Autor:
Bruno Paiva, Marcos André Gonçalves, Leonardo Chaves Dutra da Rocha, Milena Soriano Marcolino, Fernanda Cristina Barbosa Lana, Maira Viana Rego Souza-Silva, Jussara M Almeida, Polianna Delfino Pereira, Claudio Moisés Valiense de Andrade, Angélica Gomides dos Reis Gomes, Maria Angélica Pires Ferreira, Frederico Bartolazzi, Manuela Furtado Sacioto, Ana Paula Boscato, Milton Henriques Guimarães-Júnior, Priscilla Pereira dos Reis, Felício Roberto Costa, Alzira de Oliveira Jorge, Laryssa Reis Coelho, Marcelo Carneiro, Thaís Lorenna Souza Sales, Silvia Ferreira Araújo, Daniel Vitório Silveira, Karen Brasil Ruschel, Fernanda Caldeira Veloso Santos, Evelin Paola de Almeida Cenci, Luanna Silva Monteiro Menezes, Fernando Anschau, Maria Aparecida Camargos Bicalho, Euler Roberto Fernandes Manenti, Renan Goulart Finger, Daniela Ponce, Filipe Carrilho de Aguiar, Luiza Margoto Marques, Luís César de Castro, Giovanna Grünewald Vietta, Mariana Frizzo de Godoy, Mariana do Nascimento Vilaça, Vivian Costa Morais
Publikováno v:
JMIR Medical Informatics, Vol 12, p e54246 (2024)
BackgroundProper analysis and interpretation of health care data can significantly improve patient outcomes by enhancing services and revealing the impacts of new technologies and treatments. Understanding the substantial impact of temporal shifts in
Externí odkaz:
https://doaj.org/article/b2c0e6bc40374f349b91cb8a5eb66433
Autor:
Noemí Puig, Cristina Agulló, Teresa Contreras, José-Juan Pérez, Irene Aires, María-José Calasanz, Ramón García-Sanz, Sergio Castro, Joaquín Martínez-López, Paula Rodríguez-Otero, Verónica González-Calle, Marta S González, Albert Oriol, Norma C Gutiérrez, Rafael Ríos-Tamayo, Laura Rosiñol, Miguel-Ángel Álvarez, Joan Bargay, Ana-Pilar González-Rodríguez, Adrián Alegre, Fernando Escalante, María-Belén Iñigo, Javier de la Rubia, Ana-Isabel Teruel, Felipe de Arriba, Luis Palomera, Miguel T Hernández, Javier López-Jiménez, Marta Reinoso, Aránzazu García-Mateo, Enrique M Ocio, Joan Bladé, Juan-José Lahuerta, María-Teresa Cedena, Bruno Paiva, Jesús F San Miguel, María-Victoria Mateos
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
The value of quantitative immunoprecipitation mass spectrometry (QIP-MS) to identify the M-protein is being investigated in patients with monoclonal gammopathies but no data are yet available in high-risk smoldering myeloma (HRsMM). We have therefore
Externí odkaz:
https://doaj.org/article/c81a444b8f6e434cb89c96b45ea2aec6
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), long COVID (LC) and post-COVID-19 vaccine syndrome show similarities in their pathophysiology and clinical manifestations. These disorders are related to viral or adjuvant persistence, i
Externí odkaz:
https://doaj.org/article/9d6847e8373448a08473824f1b656004
Autor:
Cirino Botta, Cristina Perez, Marta Larrayoz, Noemi Puig, Maria-Teresa Cedena, Rosalinda Termini, Ibai Goicoechea, Sara Rodriguez, Aintzane Zabaleta, Aitziber Lopez, Sarai Sarvide, Laura Blanco, Daniele M. Papetti, Marco S. Nobile, Daniela Besozzi, Massimo Gentile, Pierpaolo Correale, Sergio Siragusa, Albert Oriol, Maria Esther González-Garcia, Anna Sureda, Felipe de Arriba, Rafael Rios Tamayo, Jose-Maria Moraleda, Mercedes Gironella, Miguel T. Hernandez, Joan Bargay, Luis Palomera, Albert Pérez-Montaña, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo Roccaro, Alberto Orfao, Joaquin Martinez-Lopez, Laura Rosiñol, Juan-José Lahuerta, Joan Blade, Maria-Victoria Mateos, Jesús F. San-Miguel, Jose-Angel Martinez Climent, Bruno Paiva, the Programa Para el Estudio de la Terapéutica en Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) cooperative group, the iMMunocell study group
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tumor recognition by T cells is essential for antitumor immunity. A comprehensive characterization of T cell diversity may be key to understanding the success of immunomodulatory drugs and failure of PD-1 blockade in tumors such as multiple
Externí odkaz:
https://doaj.org/article/2de8f8a904e64dd0bd9521c3f7eaa173
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-30 (2023)
Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection, autoimmunity, chronic inflammatory state, viral reactivat
Externí odkaz:
https://doaj.org/article/011b41da30dc460485bf765d2c768637
Autor:
Verónica González-Calle, Paula Rodríguez-Otero, Anna Sureda, Felipe de Arriba, Marta Reinoso, Paz Ribas, Ana Pilar González-Rodríguez, Yolanda González, Albert Oriol, Joaquín Martínez-López, Marta Sonia González, Miguel T. Hernández, Maialen Sirvent, Teresa Cedena, Noemí Puig, Bruno Paiva, Joan Bladé, Juan José Lahuerta, Jesús F. San-Miguel, María-Victoria Mateos
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
The treatment landscape for multiple myeloma has significantly evolved in the last decade. Notwithstanding, a large proportion of patients continue to relapse and novel combinations continue to be needed. In this phase 2 study, selinexor, a first-in-
Externí odkaz:
https://doaj.org/article/ee8847a91f344d7fa309aa58a2634a3b
Autor:
Sunil Lakhwani, Laura Rosiñol, Noemí Puig, Miguel-Angel Pico-Picos, Laura Medina-González, Joaquín Martínez-López, Bruno Paiva, María-Teresa Cedena, Albert Oriol, Rafael Ríos-Tamayo, María-Jesús Blanchard, Isidro Jarque, Joan Bargay, José-María Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Isabel Krsnik, Esther González, Luis Felipe Casado, Josep M Martí, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda González-Montes, Cristina Motlló, Javier De La Cruz, Rafael Alonso, María-Victoria Mateos, Joan Bladé, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
Immunoparesis (IP) in multiple myeloma (MM) patients can be measured by classic assessment of immunoglobulin (Ig) levels or by analysis of the uninvolved heavy/light chain pair of the same immunoglobulin (uHLC) by the Hevylite® assay. In this stu
Externí odkaz:
https://doaj.org/article/cd13fee267b943f2862a37b772331fa1