Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Bruno P Meloni"'
Autor:
Diego Milani, Megan C Bakeberg, Jane L Cross, Vince W Clark, Ryan S Anderton, David J Blacker, Neville W Knuckey, Bruno P Meloni
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193884 (2018)
We have previously demonstrated that arginine-rich and poly-arginine peptides possess potent neuroprotective properties, with poly-arginine peptide R18 identified as being highly effective at reducing infarct volume following middle cerebral artery o
Externí odkaz:
https://doaj.org/article/55586b60a51e4c1bba38d80f460e6beb
Autor:
Gurkiran Kaur Flora, Ryan S. Anderton, Bruno P. Meloni, Gilles J. Guillemin, Neville W. Knuckey, Gabriella MacDougall, Vance Matthews, Sherif Boulos
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e12842- (2023)
Externí odkaz:
https://doaj.org/article/e097b904f3e44e5cb97267dff0742e02
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2089 (2023)
In Parkinson’s disease (PD), gut inflammation is hypothesised to contribute to α-synuclein aggregation, but gastrointestinal α-synuclein expression is poorly characterised. Cationic arginine-rich peptides (CARPs) are an emerging therapeutic optio
Externí odkaz:
https://doaj.org/article/f1167c12c26642c089715e0db44a2a72
Autor:
Delin Liu, Youshui Gao, Jiao Liu, Yigang Huang, Junhui Yin, Yuyao Feng, Linjing Shi, Bruno P. Meloni, Changqing Zhang, Minghao Zheng, Junjie Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-18 (2021)
Abstract As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion frequently undergoes morphological or positional changes when responding to various stresses and energy demands. In addition to intracellular changes, mitoc
Externí odkaz:
https://doaj.org/article/87c27202a94e4711bfe331fa4e89b829
Autor:
Somayra S. A. Mamsa, Bruno P. Meloni
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
A substantial body of evidence indicates cationic, arginine-rich peptides (CARPs) are effective therapeutic compounds for a range of neurodegenerative pathologies, with beneficial effects including the reduction of excitotoxic cell death and mitochon
Externí odkaz:
https://doaj.org/article/526fdf7e0aa5426a8fdd1186292a6b91
Autor:
Gabriella MacDougall, Ryan S. Anderton, Frank L. Mastaglia, Neville W. Knuckey, Bruno P. Meloni
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 17-33 (2019)
Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustained efforts to develop clinically effective neuroprotective therapies, presently there is no clinically available neu
Externí odkaz:
https://doaj.org/article/155a64dbda5f4903b22592a84aac04bc
Publikováno v:
Journal of Thrombosis and Thrombolysis. 54:172-182
The poly-arginine peptides R18D and R18 represent novel potential neuroprotective treatments for acute ischaemic stroke. Here we examined whether R18D and R18 had any significant effects on the thrombolytic activity of alteplase (tPA) and tenecteplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7108e9e930fac121d332520be84234
https://doi.org/10.1007/s11239-022-02642-4
https://doi.org/10.1007/s11239-022-02642-4
Autor:
Gabriella MacDougall, Ryan S. Anderton, Amy Trimble, Frank L. Mastaglia, Neville W. Knuckey, Bruno P. Meloni
Publikováno v:
Molecules, Vol 25, Iss 13, p 2977 (2020)
Recent studies have highlighted that a novel class of neuroprotective peptide, known as cationic arginine-rich peptides (CARPs), have intrinsic neuroprotective properties and are particularly effective anti-excitotoxic agents. As such, the present st
Externí odkaz:
https://doaj.org/article/052373e68f1d49f6b407a510230b0137
Autor:
Junhui Yin, Junjie Gao, Delin Liu, Minghao Zheng, Linjing Shi, You-Shui Gao, Yuyao Feng, Yigang Huang, Bruno P. Meloni, Jiao Liu, Changqing Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-18 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion frequently undergoes morphological or positional changes when responding to various stresses and energy demands. In addition to intracellular changes, mitochondria c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50954f265f88f3f2c5f7615eee601493
https://doaj.org/article/87c27202a94e4711bfe331fa4e89b829
https://doaj.org/article/87c27202a94e4711bfe331fa4e89b829
Autor:
Kirk W. Feindel, Diego Milani, Vince W. Clark, Bruno P. Meloni, Neville W. Knuckey, Adam B. Edwards, Ryan S. Anderton, Michael Bynevelt, David Blacker
Publikováno v:
Neurochemical Research. 46:1166-1176
Poly-arginine peptides R18 and R18D have previously been demonstrated to be neuroprotective in ischaemic stroke models. Here we examined the proteolytic stability and efficacy of R18 and R18D in reducing infarct core growth and preserving the ischaem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050b40c2e26ffc1d406f295e6b749710
https://doi.org/10.1007/s11064-021-03251-y
https://doi.org/10.1007/s11064-021-03251-y