Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Bruno Nobili"'
Autor:
Carlo Tolone, Giulia Bellini, Francesca Punzo, Alfonso Papparella, Erasmo Miele, Alessandra Vitale, Bruno Nobili, Caterina Strisciuglio, Francesca Rossi
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185822 (2017)
Iron deficiency anemia in celiac disease is related to impaired duodenal mucosal uptake, due to villous atrophy. Iron enters the enterocytes through an apical divalent metal transporter, DMT1. Different DMT1 transcripts have been identified, dependin
Externí odkaz:
https://doaj.org/article/f65821bffd8141469bc36997b177b9f1
Autor:
Giulia Bellini, Anna Grandone, Marco Torella, Emanuele Miraglia del Giudice, Bruno Nobili, Laura Perrone, Sabatino Maione, Francesca Rossi
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140142 (2015)
The ovary is an important site where gene variants modulate pubertal timing. The cannabinoid receptor 2 (CB2) is expressed in the ovary, plays a role in folliculogenesis and ovulation, and can be modulated by estrogens. Obesity is strictly associated
Externí odkaz:
https://doaj.org/article/c41c23372288424faa114a457d446333
Autor:
Francesca Rossi, Silverio Perrotta, Giulia Bellini, Livio Luongo, Chiara Tortora, Dario Siniscalco, Matteo Francese, Marco Torella, Bruno Nobili, Vincenzo Di Marzo, Sabatino Maione
Publikováno v:
Haematologica, Vol 99, Iss 12 (2014)
The pathogenesis of bone resorption in β-thalassemia major is multifactorial and our understanding of the underlying molecular and cellular mechanisms remains incomplete. Considering the emerging importance of the endocannabinoid/endovanilloid syste
Externí odkaz:
https://doaj.org/article/9745baa3898c446aa16c32f30d55cab8
Autor:
Silverio Perrotta, Daniel P. Stiehl, Francesca Punzo, Saverio Scianguetta, Adriana Borriello, Debora Bencivenga, Maddalena Casale, Bruno Nobili, Silvia Fasoli, Adriana Balduzzi, Lilla Cro, Katarzyna J. Nytko, Roland H. Wenger, Fulvio Della Ragione
Publikováno v:
Haematologica, Vol 98, Iss 10 (2013)
Hypoxia-inducible factor 2α (HIF-2α) plays a pivotal role in the balancing of oxygen requirements throughout the body. The protein is a transcription factor that modulates the expression of a wide array of genes and, in turn, controls several key p
Externí odkaz:
https://doaj.org/article/5a146d963b1c41e5957f68f9e07735db
Autor:
Francesca Rossi, Maria Ester Bernardo, Giulia Bellini, Livio Luongo, Antonella Conforti, Iolanda Manzo, Francesca Guida, Luigia Cristino, Roberta Imperatore, Stefania Petrosino, Bruno Nobili, Vincenzo Di Marzo, Franco Locatelli, Sabatino Maione
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80022 (2013)
Mesenchymal stromal cells are non-hematopoietic, multipotent progenitor cells producing cytokines, chemokines, and extracellular matrix proteins that support hematopoietic stem cell survival and engraftment, influence immune effector cell development
Externí odkaz:
https://doaj.org/article/6a34c07ff6d54117a5ef39e4162983be
Autor:
Francesca Rossi, Silvia Mancusi, Giulia Bellini, Domenico Roberti, Francesca Punzo, Simona Vetrella, Sofia Maria Rosaria Matarese, Bruno Nobili, Sabatino Maione, Silverio Perrotta
Publikováno v:
Haematologica, Vol 96, Iss 12 (2011)
Immune thrombocytopenic purpura is an acquired autoimmune disorder that is the most common cause of thrombocytopenia in children. The endocannabinoid system is involved in immune regulation. We evaluated a common missense variant (CAA/CGG; Q63R) of t
Externí odkaz:
https://doaj.org/article/46f42e6a26e34aeebfba9243ef4757ee
Autor:
Silverio Perrotta, Valeria Cucciolla, Marcella Ferraro, Luisa Ronzoni, Annunziata Tramontano, Francesca Rossi, Anna Chiara Scudieri, Adriana Borriello, Domenico Roberti, Bruno Nobili, Maria Domenica Cappellini, Adriana Oliva, Giovanni Amendola, Anna Rita Migliaccio, Patrizia Mancuso, Ines Martin-Padura, Francesco Bertolini, Donghoon Yoon, Josef T Prchal, Fulvio Della Ragione
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12015 (2010)
BackgroundGain-of-function of erythropoietin receptor (EPOR) mutations represent the major cause of primary hereditary polycythemia. EPOR is also found in non-erythroid tissues, although its physiological role is still undefined.Methodology/principal
Externí odkaz:
https://doaj.org/article/c749460bfd1e4e51998c1c626fd9cba6
Autor:
Franco Locatelli, Marco Zecca, Andrea Pession, Giuseppe Morreale, Daniela Longoni, Paolo Di Bartolomeo, Fulvio Porta, Franca Fagioli, Bruno Nobili, Maria Ester Bernardo, Chiara Messina
Publikováno v:
Haematologica, Vol 92, Iss 10 (2007)
Background and Objectives Hematopoietic stem cell transplantation (HSCT) still represents the only treatment potentially able to prevent/rescue the development of marrow failure and myeloid malignancies in patients with Fanconi anemia (FA). While in
Externí odkaz:
https://doaj.org/article/c5c6fb392f8e460bad74e6c6f4974876
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity
Autor:
Francesca Rossi, Bruno Nobili, Livio Luongo, Sabatino Maione, Chiara Tortora, Iolanda Manzo, Nicola Colacurci, Giulia Bellini, Francesca Punzo, Marco Torella
Publikováno v:
Pharmacological Research. 115:267-274
In this study, we investigated the role of the endovanilloid/endocannabinoid system in the glucocorticoid-induced osteoclast overactivity. Receptorial and enzymatic component of the endovanilloid/endocannabinoid system are expressed in bone cells, an
Autor:
Francesca Rossi, Natascia Campostrini, A. Alessandrella, Silverio Perrotta, Renata Auricchio, Annamaria Staiano, Bruno Nobili, Massimo Martinelli, Caterina Strisciuglio, Erasmo Miele, Domenico Girelli
Publikováno v:
Journal of Crohn's and Colitis. 10:566-574
We sought to correlate hepcidin levels in inflammatory bowel disease [IBD] children with disease activity, inflammatory markers, and iron load test [ILT] and to compare IBD patients with coeliac and healthy patients.Between December 2012 and June 201