T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

Autor: Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima

Publikováno v: Cell Reports, Vol 42, Iss 11, Pp 113448- (2023)

Summary: CD4+ T cells are key components of the immune response during lung infections and can mediate protection against tuberculosis (TB) or influenza. However, CD4+ T cells can also promote lung pathology during these infections, making it unclear

Externí odkaz: https://doaj.org/article/fe5978ef17a34b0d8f92e8f6d5272a3f

Morphological, cellular, and molecular basis of brain infection in COVID-19 patients

Autor: Fernanda Crunfli, Victor C. Carregari, Flavio P. Veras, Lucas S. Silva, Mateus Henrique Nogueira, André Saraiva Leão Marcelo Antunes, Pedro Henrique Vendramini, Aline Gazzola Fragnani Valença, Caroline Brandão-Teles, Giuliana da Silva Zuccoli, Guilherme Reis-de-Oliveira, Lícia C. Silva-Costa, Verônica Monteiro Saia-Cereda, Bradley J. Smith, Ana Campos Codo, Gabriela F de Souza, Stéfanie P. Muraro, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Ícaro Maia Santos de Castro, Bruno Marcel Melo, Glaucia M. Almeida, Egidi Mayara Silva Firmino, Isadora Marques Paiva, Bruna Manuella Souza Silva, Rafaela Mano Guimarães, Niele D. Mendes, Raíssa L. Ludwig, Gabriel P. Ruiz, Thiago L. Knittel, Gustavo G. Davanzo, Jaqueline Aline Gerhardt, Patrícia Brito Rodrigues, Julia Forato, Mariene Ribeiro Amorim, Natália S. Brunetti, Matheus Cavalheiro Martini, Maíra Nilson Benatti, Sabrina S. Batah, Li Siyuan, Rafael B. João, Ítalo K. Aventurato, Mariana Rabelo de Brito, Maria J. Mendes, Beatriz A. da Costa, Marina K. M. Alvim, José Roberto da Silva Júnior, Lívia L. Damião, Iêda Maria P. de Sousa, Elessandra D. da Rocha, Solange M. Gonçalves, Luiz H. Lopes da Silva, Vanessa Bettini, Brunno M. Campos, Guilherme Ludwig, Lucas Alves Tavares, Marjorie Cornejo Pontelli, Rosa Maria Mendes Viana, Ronaldo B. Martins, Andre Schwambach Vieira, José Carlos Alves-Filho, Eurico Arruda, Guilherme Gozzoli Podolsky-Gondim, Marcelo Volpon Santos, Luciano Neder, André Damasio, Stevens Rehen, Marco Aurélio Ramirez Vinolo, Carolina Demarchi Munhoz, Paulo Louzada-Junior, Renê Donizeti Oliveira, Fernando Q. Cunha, Helder I. Nakaya, Thais Mauad, Amaro Nunes Duarte-Neto, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilario Nascimento Saldiva, Alessandro S. Farias, Fernando Cendes, Pedro Manoel M. Moraes-Vieira, Alexandre T. Fabro, Adriano Sebollela, José L. Proença-Modena, Clarissa L. Yasuda, Marcelo A. Mori, Thiago M. Cunha, Daniel Martins-de-Souza

Publikováno v: Proceedings of the National Academy of Sciences. 119

Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently characterized as part of “long COVID-19” syndrome) has been frequently observ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47ddeff3c7b9a059a857e00fd4d3c15
https://doi.org/10.1073/pnas.2200960119