Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Bruno Lopes Abbadi"'
Autor:
Gisele Cassão, Krist Helen Antunes, João Ismael Budelon Gonçalvez, Leonardo Duarte Santos, Bruno Lopes Abbadi, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso, Christian Pasquali, Renato T. Stein, Ana Paula Duarte de Souza
Publikováno v:
Frontiers in Virology, Vol 3 (2023)
OM-85 is a bacterial lysate from common respiratory tract pathogens, with an excellent safety profile, widely used to prevent recurrent respiratory tract infections. Several studies have been reporting the immunomodulating properties and antiviral ro
Externí odkaz:
https://doaj.org/article/65130d6acd124b37b7a0b73ab7087035
Autor:
Luiza Galina, Fernanda S. M. Hopf, Bruno Lopes Abbadi, Nathalia D. de Moura Sperotto, Alexia M. Czeczot, Mario A. Duque-Villegas, Marcia Alberton Perello, Letícia Beatriz Matter, Eduardo Vieira de Souza, Tanya Parish, Pablo Machado, Luiz A. Basso, Cristiano V. Bizarro
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Tuberculosis (TB) remains one of the leading causes of death due to a single pathogen. The emergence and proliferation of multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) represent compelling reasons to invest in
Externí odkaz:
https://doaj.org/article/b057ae3731e74dc39aac63be0054d6c6
Autor:
Alexia de Matos Czeczot, Candida Deves Roth, Rodrigo Gay Ducati, Kenia Pissinate, Raoní Scheibler Rambo, Luís Fernando Saraiva Macedo Timmers, Bruno Lopes Abbadi, Fernanda Souza Macchi, Víctor Zajaczkowski Pestana, Luiz Augusto Basso, Pablo Machado, Cristiano Valim Bizarro
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 847-855 (2021)
The dihydroneopterin aldolase (DHNA, EC 4.1.2.25) activity of FolB protein is required for the conversion of 7,8-dihydroneopterin (DHNP) to 6-hydroxymethyl-7,8-dihydropterin (HP) and glycolaldehyde (GA) in the folate pathway. FolB protein from Mycoba
Externí odkaz:
https://doaj.org/article/adfbb94f578e4e9eae055faaa791c0f4
Autor:
Mario Alejandro Duque-Villegas, Bruno Lopes Abbadi, Paulo Ricardo Romero, Letícia Beatriz Matter, Luiza Galina, Pedro Ferrari Dalberto, Valnês da Silva Rodrigues-Junior, Rodrigo Gay Ducati, Candida Deves Roth, Raoní Scheibler Rambo, Eduardo Vieira de Souza, Marcia Alberton Perello, Héctor Ricardo Morbidoni, Pablo Machado, Luiz Augusto Basso, Cristiano Valim Bizarro
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT The epidemiological importance of mycobacterial species is indisputable, and the necessity to find new molecules that can inhibit their growth is urgent. The shikimate pathway, required for the synthesis of important bacterial metabolites, r
Externí odkaz:
https://doaj.org/article/7923956a598648dcb7e2d9179f3e718c
Autor:
Renata Jardim Etchart, Raoní S. Rambo, Bruno Lopes Abbadi, Nathalia Sperotto, Christiano Ev Neves, Fernanda Fries Silva, Maiele Dornelles, Lovaine Duarte, Fernanda Souza Macchi, Marcia Alberton Perelló, Rogério Vescia Lourega, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado
Publikováno v:
Molecules, Vol 26, Iss 17, p 5148 (2021)
Tuberculosis has been described as a global health crisis since the 1990s, with an estimated 1.4 million deaths in the last year. Herein, a series of 20 1H-indoles were synthesized and evaluated as in vitro inhibitors of Mycobacterium tuberculosis (M
Externí odkaz:
https://doaj.org/article/f94f651a01614b1b911b4aa908223ee3
Autor:
Gisele Cassão, Krist Helen Antunes, João Ismael Budelon Gonçalvez, Leonardo Duarte Santos, Bruno Lopes Abbadi, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso, Christian Pasquali, Renato T. Stein, Ana Paula Duarte de Souza
OM-85 is a bacterial lysate from common respiratory tract pathogens, with an excellent safety profile, widely used to prevent recurrent respiratory tract infections. Several studies have been reporting the antiviral roles of OM-85. Here we demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4270a645c3ceef7ccbfb27478e0b74d1
https://doi.org/10.1101/2022.07.29.502045
https://doi.org/10.1101/2022.07.29.502045
Autor:
Leonardo Duarte Santos, Krist Helen Antunes, Gisele Cassão, João Ismael Gonçalves, Bruno Lopes Abbadi, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado, Ana Paula Duarte de Souza, Bárbara Nery Porto
Publikováno v:
International Immunopharmacology. 117:109954
We analyzed the ability of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) itself and SARS-CoV-2-IgG immune complexes to trigger human monocyte necroptosis. SARS-CoV-2 was able to induce monocyte necroptosis dependently of MLKL activatio
Autor:
Talita Freitas de Freitas, Candida Deves Roth, Bruno Lopes Abbadi, Fernanda Souza Macchi Hopf, Marcia Alberton Perelló, Alexia de Matos Czeczot, Eduardo Vieira de Souza, Ana Flávia Borsoi, Pablo Machado, Cristiano Valim Bizarro, Luiz Augusto Basso, Luis Fernando Saraiva Macedo Timmers
Publikováno v:
Journal of computer-aided molecular design.
Tuberculosis (TB) is one of the main causes of death from a single pathological agent, Mycobacterium tuberculosis (Mtb). In addition, the emergence of drug-resistant TB strains has exacerbated even further the treatment outcome of TB patients. It is
Autor:
Ana Flávia Borsoi, Laura Manzoli Alice, Nathalia Sperotto, Alessandro Silva Ramos, Bruno Lopes Abbadi, Fernanda Souza Macchi Hopf, Adilio da Silva Dadda, Raoní S. Rambo, Rodrigo Braccini Madeira Silva, Josiane Delgado Paz, Kenia Pissinate, Mauro Neves Muniz, Christiano Ev Neves, Luiza Galina, Laura Calle González, Marcia Alberton Perelló, Alexia de Matos Czeczot, Mariana Leyser, Sílvia Dias de Oliveira, Graziela de Araújo Lock, Bibiana Verlindo de Araújo, Teresa Dalla Costa, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado
Publikováno v:
ACS medicinal chemistry letters. 13(8)
Using cycloalkyl and electron-donating groups to decrease the carbonyl electrophilicity, a novel series of 2-(quinoline-4-yloxy)acetamides was synthesized and evaluated as
Autor:
Juliana Schons Gularte, Mariana Soares da Silva, Micheli Filippi, Meriane Demoliner, Karoline Schallenberger, Alana Witt Hansen, Vyctoria Malayhka de Abreu Góes Pereira, Fágner Henrique Heldt, Viviane Girardi, Matheus Nunes Weber, Paula Rodrigues de Almeida, Bruno Lopes Abbadi, Maiele Dornelles, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso, Odir Antonio Dellagostin, Juliane Deise Fleck, Fernando Rosado Spilki
Publikováno v:
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 53(3)
Different approaches are in use to improve our knowledge about the causative agent of coronavirus disease (COVID-19). Cell culture-based methods are the better way to perform viral isolation, evaluate viral infectivity, and amplify the virus. Further