Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bruno Lionne"'
Autor:
Judith Sudhalter, Qiang Gao, Stephan Reiling, Isabelle Schreiber, Albane Courjaud, Jack Pollard, Eric Yang, Luc Bonnet, Joshua Murtie, Carlos Garcia-Echeverria, Matthieu Barrague, Fangxian Sun, Timothy He, Claudine Grepin, Monsif Bouaboula, Francisco Adrian, Bailin Zhang, Malvika Koundinya, M. Paola Castaldi, Gaetan Touyer, Bruno Lionne, Mark Munson, Richard Newcombe, Isabelle Menguy, Rosalia Arrebola, Stuart Licht, Yanjun Wang, Christopher Winter, Ronald Tomlinson, Patricia Gee, Hui Cao, Christelle Perrault, Stephanie Vougier, Aaron J. Morris, David Harper, Brigitte Benhamou, Hong Cheng, Ivan Cornella-Taracido, Daniel Simard
Publikováno v:
Cell Chemical Biology. 25:705-717.e11
Summary Activating KRAS mutations are major oncogenic drivers in multiple tumor types. Synthetic lethal screens have previously been used to identify targets critical for the survival of KRAS mutant cells, but their application to drug discovery has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8adef1cb348b566c4cf6075801bafc
https://doi.org/10.1016/j.chembiol.2018.03.005
https://doi.org/10.1016/j.chembiol.2018.03.005
Autor:
Brigitte Benhamou, Ivan Cornella-Taracido, Christelle Perrault, Stephanie Vougier, Bruno Lionne, Ronald Tomlinson, Francisco Adrian, Hui Cao, David P. Harper, Maria Paola Castaldi, Isabelle Schreiber, Jack Pollard, Malvika Koundinya, Monsif Bouaboula, Albane Courjaud, Gaetan Touyer, Rosalia Arrebola, Luc Bonnet, Aaron J. Morris, Daniel Simard, Stephan Reiling, Judith Sudhalter, Carlos Garcia-Echeverria, Claudine Grepin, Isabelle Menguy
Publikováno v:
Cancer Research. 73:2243-2243
Activating KRAS mutations are oncogenic and prevalent in multiple tumor types, being found in as high as 90% of pancreatic carcinomas and 50% of colorectal carcinomas. In spite of its attractiveness for therapeutic intervention to date no KRAS-target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553379a34eabd08813663c0a4b846c15
https://doi.org/10.1158/1538-7445.am2013-2243
https://doi.org/10.1158/1538-7445.am2013-2243