Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bruno Lima Giacobbo"'
Autor:
Özgün Özalay, Tomas Mediavilla, Bruno Lima Giacobbo, Robin Pedersen, Daniel Marcellino, Greger Orädd, Anna Rieckmann, Fahad Sultan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The human aging brain is characterized by changes in network efficiency that are currently best captured through longitudinal resting-state functional MRI (rs-fMRI). These studies however are challenging due to the long human lifespan. Here
Externí odkaz:
https://doaj.org/article/bd0dc510930d41da8f27604d19ff40ac
Autor:
Wejdan M. Arif, Philip H. Elsinga, Roel J.H.M. Steenbakkers, Walter Noordzij, Lara Barazzuol, Kelvin N.G. Wei Siang, Charlotte L. Brouwer, Bruno Lima Giacobbo, Rudi A.J.O. Dierckx, Ronald J.H. Borra, Gert Luurtsema
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 42, Iss , Pp 100652- (2023)
Background and purpose: Previous pre-clinical research using [18F]FDG-PET has shown that whole-brain photon-based radiotherapy can affect brain glucose metabolism. This study, aimed to investigate how these findings translate into regional changes in
Externí odkaz:
https://doaj.org/article/231ee542b3c5494ea02c6f0ddaab3c08
Autor:
Rodrigo Moraga-Amaro, Cyprien G. J. Guerrin, Luiza Reali Nazario, Bruno Lima Giacobbo, Rudi A. J. O. Dierckx, Jimmy Stehberg, Erik F. J. de Vries, Janine Doorduin
Publikováno v:
Stress, Vol 25, Iss 1, Pp 145-155 (2022)
Worldwide, millions of people suffer from treatment-resistant depression. Ketamine, a glutamatergic receptor antagonist, can have a rapid antidepressant effect even in treatment-resistant patients. A proposed mechanism for the antidepressant effect o
Externí odkaz:
https://doaj.org/article/54be6d66690f44e78b6a1ee5fbc7ed8f
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/303a74411c114b4096e960a4f5bdccb1
Autor:
Bruno Lima Giacobbo, Özgün Özalay, Tomas Mediavilla, Madelene Ericsson, Jan Axelsson, Anna Rieckmann, Fahad Sultan, Daniel Marcellino
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
To study the aging human brain requires significant resources and time. Thus, mice models of aging can provide insight into changes in brain biological functions at a fraction of the time when compared to humans. This study aims to explore changes in
Externí odkaz:
https://doaj.org/article/0d6473bcb6cf457d9dfe529392e862e9
Autor:
Márcio Silveira Corrêa, Bruno Lima Giacobbo, Kelem Vedovelli, Daiane Borba de Lima, Pamela Ferrari, Irani Iracema de Lima Argimon, Julio Cesar Walz, Elke Bromberg
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0162619 (2016)
OBJECTIVES:Older familial caregivers of Alzheimer's disease patients are subjected to stress-related cognitive and psychophysiological dysfunctions that may affect their quality of life and ability to provide care. Younger caregivers have never been
Externí odkaz:
https://doaj.org/article/87e6497f9b7c4fe5917f113fd04a5db2
Autor:
Erik F. J. de Vries, Rudi Dierckx, Anna Schildt, Antoon T.M. Willemsen, Jurgen W. A. Sijbesma, Vesna Sossi, Rodrigo Moraga-Amaro, Bruno Lima-Giacobbo, Janine Doorduin
Publikováno v:
Molecular Imaging and Biology, 22(4), 931-939. SPRINGER
Purpose: [18F]Fluoroethoxybenzovesamicol ([18F]FEOBV) is a radioligand for the vesicular acetylcholine transporter (VAChT), a marker of the cholinergic system. We evaluated the quantification of [18F]FEOBV in rats in control conditions and after part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63913b3984ed26ed4c6c707b865982b4
https://doi.org/10.1007/s11307-019-01466-8
https://doi.org/10.1007/s11307-019-01466-8
Autor:
Aren van Waarde, Jurgen W. A. Sijbesma, Antoon T. M. Willemsen, Erik F. J. de Vries, Vesna Sossi, Janine Doorduin, Anna Schildt, Rodrigo Moraga-Amaro, Bruno Lima Giacobbo, Rudi Dierckx
Publikováno v:
Molecular pharmaceutics, 17(3), 865-872. AMER CHEMICAL SOC INC
Molecular Pharmaceutics
Molecular Pharmaceutics
The interaction of dopaminergic and cholinergic neurotransmission in, e.g., Parkinson's disease has been well established. Here, D2 receptor antagonists were used to assess changes in [18F]-FEOBV binding to the vesicular acetylcholine transporter (VA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971ddf5f0fbf079fd12ed18375790990
https://doi.org/10.1021/acs.molpharmaceut.9b01129
https://doi.org/10.1021/acs.molpharmaceut.9b01129
Autor:
null Héctor M. Estévez‐Silva, null Tomás Mediavilla, null Bruno Lima Giacobbo, null Xijia Liu, null Fahad R. Sultan, null Daniel J. Marcellino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dd2fd63b0200dd50c11ecd56d3f088c
https://doi.org/10.1111/ejn.15608/v2/response1
https://doi.org/10.1111/ejn.15608/v2/response1
Autor:
Héctor M. Estévez‐Silva, Tomás Mediavilla, Bruno Lima Giacobbo, Xijia Liu, Fahad R. Sultan, Daniel J. Marcellino
Publikováno v:
The European journal of neuroscience. 55(5)
Amyotrophic lateral sclerosis (ALS) is a lethal and incurable neurodegenerative disease due to the loss of upper and lower motor neurons, which leads to muscle weakness, atrophy, and paralysis. Sigma-1 receptor (σ-1R) is a ligand-operated protein th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500ba64c546e0bb6031c26d25872fde4
https://pubmed.ncbi.nlm.nih.gov/35080077
https://pubmed.ncbi.nlm.nih.gov/35080077