Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Bruno Lacarelle"'
Autor:
Clémence Marin, Anis Krache, Chloé Palmaro, Mathilde Lucas, Valentin Hilaire, Renée Ugdonne, Bénédicte De Victor, Sylvie Quaranta, Caroline Solas, Bruno Lacarelle, Joseph Ciccolini
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 761-768 (2020)
Detecting patients with dihydropyrimidine dehydrogenase (DPD) deficiency is becoming a major concern in clinical oncology. Monitoring physiologic plasma uracil and/or plasma uracil‐to‐dihydrouracil metabolic ratio is a common surrogate frequently
Externí odkaz:
https://doaj.org/article/863273e40aab44e7a9196b17925d03a8
Autor:
Etienne Dougy, Dominique Figarella-Branger, Pierre-Emmanuel Morange, Annachiara De Sandre-Giovannoli, Bruno Lacarelle, Karine Bertaux, Karine Pedeillier, Noémie Saut, Carine Jiguet-Jiglaire, Soutsakhone Tong, Karine Achache
Publikováno v:
Open Journal of Bioresources, Vol 7, Iss 1 (2020)
The biobank of the Assistance Publique Hôpitaux de Marseille (AP-HM) works as a multi-site biobank around one Quality Management System. The biobank works on the collection, preparation, storage and release of biological resources and their associat
Externí odkaz:
https://doaj.org/article/34fff7e41f594f41978c567f03f61f63
Autor:
Atakan Hernandez, Valerie Lacroze, Natalia Doudka, Jenny Becam, Carole Pourriere-Fabiani, Bruno Lacarelle, Caroline Solas, Nicolas Fabresse
Publikováno v:
Toxics, Vol 10, Iss 2, p 55 (2022)
The aim of this study was to develop and to validate a toxicological untargeted screening relying on LC-HRMS in meconium including the detection of the four main classes of drugs of abuse (DoA; amphetamines, cannabinoids, opioids and cocaine). The me
Externí odkaz:
https://doaj.org/article/e37cc435d4d84710be39033483cc6e82
Autor:
Vincent Madelain, Sylvain Baize, Frédéric Jacquot, Stéphanie Reynard, Alexandra Fizet, Stephane Barron, Caroline Solas, Bruno Lacarelle, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie, Jérémie Guedj
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Optimization of antiviral therapy can be crucial in the management of Ebola virus outbreaks. Here, Madelain et al. use an integrative mathematical model to correlate the dose and the time of treatment initiation with survival rate, enhanced immune re
Externí odkaz:
https://doaj.org/article/8007c9d9b043441c879ab95a1e9f13f9
Autor:
Raphaelle Fanciullino, Laure Farnault, Mélanie Donnette, Diane-Charlotte Imbs, Catherine Roche, Geoffroy Venton, Yael Berda-Haddad, Vadim Ivanov, Joseph Ciccolini, L'Houcine Ouafik, Bruno Lacarelle, Regis Costello
Publikováno v:
Blood Advances, Vol 2, Iss 5, Pp 462-469 (2018)
Abstract: Cytarabine (Ara-C) is the backbone of acute myeloid leukemia (AML) chemotherapy. Little is known about possible risk factors predictive for the frequent (ie, up to 16%) life-threatening or lethal toxicities caused by Ara-C. Ara-C is detoxif
Externí odkaz:
https://doaj.org/article/84fa2bbf99cc4db5a089006627f8586d
Autor:
Clémence Marin, Nihel Khoudour, Aurélien Millet, Dorothée Lebert, Pauline Bros, Fabienne Thomas, David Ternant, Bruno Lacarelle, Jérôme Guitton, Joseph Ciccolini, Benoit Blanchet
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 796 (2021)
Background: Different liquid chromatography tandem mass spectrometry (LC–MS/MS) methods have been published for quantification of monoclonal antibodies (mAbs) in plasma but thus far none allowed the simultaneous quantification of several mAbs, incl
Externí odkaz:
https://doaj.org/article/77c04e28bb494b1c898c4fa64aa833ae
Autor:
Florent Ferrer, Jonathan Chauvin, Bénédicte DeVictor, Bruno Lacarelle, Jean-Laurent Deville, Joseph Ciccolini
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 494 (2021)
Different target exposures with sunitinib have been proposed in metastatic renal cell carcinoma (mRCC) patients, such as trough concentrations or AUCs. However, most of the time, rather than therapeutic drug monitoring (TDM), clinical evidence is pre
Externí odkaz:
https://doaj.org/article/d3826fa31f644353abe2ce218f01f0b7
Autor:
François Becher, Joseph Ciccolini, Diane-Charlotte Imbs, Clémence Marin, Claire Fournel, Charlotte Dupuis, Nicolas Fakhry, Bertrand Pourroy, Aurélie Ghettas, Alain Pruvost, Christophe Junot, Florence Duffaud, Bruno Lacarelle, Sebastien Salas
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Administration of first-in-class anti-EGFR monoclonal antibody cetuximab is contingent upon extensive pharmacogenomic testing. However in addition to tumor genomics, drug exposure levels could play a critical, yet largely underestimated role
Externí odkaz:
https://doaj.org/article/59b1810b3de1458f856d8917cd3a443c
Autor:
Amélie Marsot, Christine Audebert, Laurence Attolini, Bruno Lacarelle, Joelle Micallef, Olivier Blin
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 19, Iss 3 (2016)
Purpose. A randomized cross-over, double blind placebo controlled study of smoked cannabis was carried out on occasional cannabis smokers. The objective of this research was to describe the pharmacokinetic parameters of THC and its metabolites in pla
Externí odkaz:
https://doaj.org/article/cd258d056fbd40838db68783b272a0d9
Autor:
Sophie Perrin, Jonathan Cremer, Olivia Faucher, Jacques Reynes, Pierre Dellamonica, Joëlle Micallef, Caroline Solas, Bruno Lacarelle, Charlotte Stretti, Elise Kaspi, Andrée Robaglia-Schlupp, Corine Nicolino-Brunet, Catherine Tamalet, Nicolas Lévy, Isabelle Poizot-Martin, Pierre Cau, Patrice Roll
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/a2440acefe4e49cd8ff0be82d2afb419