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pro vyhledávání: '"Bruno Johnson"'
DNA fragmentation factor 40 (DFF40), or the caspase-activated DNase (CAD), is an endonuclease specific for double-stranded DNA. Alterations in its function and expression have been linked to apoptosis resistance, a mechanism likely used by cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a145454abd5bfa88e419700d59bfeeb
https://doi.org/10.21203/rs.3.rs-925720/v1
https://doi.org/10.21203/rs.3.rs-925720/v1
Publikováno v:
Biochemical pharmacology. 194
The regulation of the apoptotic pathway is one of the most studied mechanisms regarding cancer cell resistance. Many mutations have been linked to drug resistance. The DNA fragmentation factor 40 (DFF40) has been gaining interest regarding cancer cel
Autor:
Valérie Malboeuf, Jacques Bernier, Guillaume Ricaud, Merve Kulbay, Bruno Johnson, Marie-Noëlle Séguin-Grignon
DNA fragmentation factor 40 (DFF40), or the caspase-activated DNase (CAD), is an endonuclease specific for double-stranded DNA. Alterations in its function and expression have been linked to apoptosis resistance, a mechanism likely used by cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e0089fe7a8f75ae455ced7d1bff2b6
https://doi.org/10.21203/rs.3.rs-198442/v1
https://doi.org/10.21203/rs.3.rs-198442/v1
Autor:
Moncef Benkhalifa, Véronique Blais, Cathy Vaillancourt, Fabien Joao, Guillaume Ricaud, Marjorie Disdier, Pierre Miron, Jacques Bernier, Bruno Johnson
Over the last few years, intrauterine administration of autologous peripheral blood mononuclear cells (PBMC) has been proposed as new immunotherapy for patients with unexplained recurrent implantation failure (RIF). In these patients, administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::154b277f0e8647ab2e6ab58c08947e48
https://doi.org/10.1101/2021.01.06.425452
https://doi.org/10.1101/2021.01.06.425452
Publikováno v:
Toxicology. 426
DNA fragmentation factor 40 (DFF40), an endonuclease, mediates the final and irreversible step of apoptosis by conducting oligonucleosomal DNA fragmentation. New emerging studies have proposed a role of DFF40 in genomic stability, besides its nucleas
Publikováno v:
Biochimica et biophysica acta. 1840(1)
Background O-linked β-N-acetylglucosamine (O-GlcNAc) is a nutrient-/stress-sensitive post-translational modification that affects nucleocytoplasmic proteins. The enzyme O-N-acetylglucosamine transferase (OGT) catalyzes the addition of O-GlcNAc, wher