Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Bruno Flamion"'
Autor:
Kaoutar Idouz, Asmae Belhaj, Benoit Rondelet, Laurence Dewachter, Bruno Flamion, Nathalie Kirschvink, Sophie Dogné
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Brain death (BD) is a complex medical state that triggers systemic disturbances and a cascade of pathophysiological processes. This condition significantly impairs both kidney function and structural integrity, thereby presenting considerable challen
Externí odkaz:
https://doaj.org/article/1a656c04218341598e07ec2c021233c9
Autor:
Emeline Puissant, Florentine Gilis, Virginie Tevel, Jean-Michel Vandeweerd, Bruno Flamion, Michel Jadot, Marielle Boonen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mucopolysaccharidosis IX is a lysosomal storage disorder caused by a deficiency in HYAL1, an enzyme that degrades hyaluronic acid at acidic pH. This disease causes juvenile arthritis in humans and osteoarthritis in the Hyal1 knockout mouse m
Externí odkaz:
https://doaj.org/article/03c97d9d9aa14651bd6e8ca906f12b2b
Autor:
Delphine del Marmol, Susanne Holtze, Nadia Kichler, Arne Sahm, Benoit Bihin, Virginie Bourguignon, Sophie Dogné, Karol Szafranski, Thomas Bernd Hildebrandt, Bruno Flamion
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Large amounts of ultra-high molecular weight hyaluronan (HA) have been described as the main cause of cancer resistance in naked mole-rats (Heterocephalus glaber, NMR). Our work examined HA metabolism in these rodents more closely. HA was lo
Externí odkaz:
https://doaj.org/article/d7085e041e044033971449e3ea7d50e2
Autor:
Céline Evrard, Emilie Faway, Evelyne De Vuyst, Olivier Svensek, Valérie De Glas, David Bergerat, Michel Salmon, Olivier De Backer, Bruno Flamion, Hélène Le-Buanec, Catherine Lambert de Rouvroit, Yves Poumay
Publikováno v:
JID Innovations, Vol 1, Iss 4, Pp 100054- (2021)
TSG-6 is a soluble protein secreted in the extracellular matrix by various cell types in response to inflammatory stimuli. TSG-6 interacts with extracellular matrix molecules, particularly hyaluronan (HA), and promotes cutaneous wound closure in mice
Externí odkaz:
https://doaj.org/article/2e132e18b1834a6ca1ebd5288fea27c9
Autor:
Cécile Onclinx, Sophie Dogne, Laurence Jadin, Fabienne Andris, Christian Grandfils, François Jouret, François Mullier, Bruno Flamion
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Hyaluronan is a major component of the extracellular matrix and glycocalyx. Its main somatic degrading enzymes are hyaluronidases 1 and 2, neither of which is active in the bloodstream. We generated hyaluronidase 2-deficient mice. These animals suffe
Externí odkaz:
https://doaj.org/article/d85b9fa8e9a84130a5c85bc0c4aa4a13
Autor:
Bruno Flamion, Jaein Seo, Sebastian Heidenreich, Melissa Ross, Andrea Phillips-Beyer, Kevin Marsh
Publikováno v:
The Patient - Patient-Centered Outcomes Research. 14:65-74
Studies recommend randomising the order of attributes in discrete choice experiments (DCEs) to avoid bias; however, in a benefit–risk setting, this may increase the cognitive burden of respondents who compare the benefits and risks of treatments, o
Autor:
Sophie Dogné, Bruno Flamion
Publikováno v:
The American Journal of Pathology. 190:768-780
Hyaluronan (HA) is a ubiquitous glycosaminoglycan of the extracellular matrix. It is present in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial glycocalyx regulates blood vessel permeability and homeostasi
Autor:
Emeline Puissant, Florentine Gilis, Virginie Tevel, Jean-Michel Vandeweerd, Bruno Flamion, Michel Jadot, Marielle Boonen
Publikováno v:
Puissant, E, Gilis, F, Tevel, V, Vandeweerd, J-M, Flamion, B, Jadot, M & Boonen, M 2022, ' Hyaluronidase 1 deficiency decreases bone mineral density in mice ', Scientific Reports, vol. 12, no. 1, 10142 . https://doi.org/10.1038/s41598-022-14473-7
Mucopolysaccharidosis IX is a lysosomal storage disorder caused by a deficiency in HYAL1, an enzyme that degrades hyaluronic acid at acidic pH. This disease causes juvenile arthritis in humans and osteoarthritis in the Hyal1 knockout mouse model. Our
Autor:
Bruno Flamion, Sophie Dogné, Arne Sahm, Susanne Holtze, Thomas B. Hildebrandt, Nadia Kichler, Delphine del Marmol, Karol Szafranski, Virginie Bourguignon, Benoît Bihin
Publikováno v:
Scientific Reports
del Marmol, D, Holtze, S, Kichler, N, Sahm, A, Bihin, B, Bourguignon, V, Dogné, S, Szafranski, K, Hildebrandt, T B & Flamion, B 2021, ' Abundance and size of hyaluronan in naked mole-rat tissues and plasma ', Scientific Reports, vol. 11, no. 1, 7951, pp. 7951 . https://doi.org/10.1038/s41598-021-86967-9
Scientific reports, 11(1):7951
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
del Marmol, D, Holtze, S, Kichler, N, Sahm, A, Bihin, B, Bourguignon, V, Dogné, S, Szafranski, K, Hildebrandt, T B & Flamion, B 2021, ' Abundance and size of hyaluronan in naked mole-rat tissues and plasma ', Scientific Reports, vol. 11, no. 1, 7951, pp. 7951 . https://doi.org/10.1038/s41598-021-86967-9
Scientific reports, 11(1):7951
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Large amounts of ultra-high molecular weight hyaluronan (HA) have been described as the main cause of cancer resistance in naked mole-rats (Heterocephalus glaber, NMR). Our work examined HA metabolism in these rodents more closely. HA was localized a
Autor:
Patricia N. Sidharta, Pierre Gueneau de Mussy, Marc Iglarz, Nicolas Guérard, Michel Burnier, Jasper Dingemanse, Grégoire Wuerzner, Marc Maillard, Bruno Flamion
Publikováno v:
Clinical pharmacology and therapeutics, vol. 109, no. 3, pp. 746-753
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics
Aprocitentan is a novel, oral, dual endothelin receptor antagonist (ERA) in development in difficult-to-control hypertension. As fluid retention and edema are concerns with ERAs, we investigated whether aprocitentan causes weight gain in healthy subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a2c9329d030e44abc38075c4315ced
https://serval.unil.ch/notice/serval:BIB_1BE20415C0D5
https://serval.unil.ch/notice/serval:BIB_1BE20415C0D5