Výsledky vyhledávání - "Bruno Fiorentino"

Akademický článek

Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

Autor: Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Bruno Fiorentino, Maria Adele Rigamonti, Laura Calosi, Carla Ghelardini

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipa

Externí odkaz: https://doaj.org/article/397e87c1d72443d895c5298fa9fe02d6

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Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

Autor: Alessandra Toti, Maria Adele Rigamonti, Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Bruno Fiorentino, Laura Calosi, Carmen Parisio, Carla Ghelardini

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3815c72dcc216720815286540f7229
https://www.frontiersin.org/article/10.3389/fphar.2020.576624/full

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Good manufacturing practice-grade fibrin gel is useful as a scaffold for human mesenchymal stromal cells and supports in vitro osteogenic differentiation

Autor: Bruno Fiorentino, Mario Petrini, Stefano Guazzini, Manuela Scarpellini, Sara Galimberti, Simone Pacini, Rita Fazzi, Delfo D'Alessandro, Luisa Trombi

Publikováno v: Transfusion. 48:2246-2251

BACKGROUND: Recently, there has been an increased interest in using mesenchymal stromal cells (MSCs) in bone tissue engineering coupled with a suitable scaffold of both biological and synthetic origin. The cells and these constructs can be combined i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83433059f1e58b68ba2679fe9c0c1828
https://doi.org/10.1111/j.1537-2995.2008.01829.x

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A new biocompatible nanoparticle delivery system for the release of fibrinolytic drugs

Autor: Claudio Farina, Federica Chiellini, Anna Maria Piras, Cristina Bartoli, Bruno Fiorentino, Emo Chiellini, Chiara Fiumi

Publikováno v: International Journal of Pharmaceutics. 357:260-271

The preparation of novel biocompatible polymeric nanoconstructs suitable to load sensitive bioactive protein agents is reported. Nanoparticles were prepared as based on hybrid polymeric matrices consisting of synthetic bioerodible alternating copolym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6d35da3f42a985185804cbfc954364
https://doi.org/10.1016/j.ijpharm.2008.01.035

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Upstream Stimulatory Factor Regulates Constitutive Expression and Hormonal Suppression of the 90K (Mac-2BP) Protein

Autor: Giorgio Napolitano, Hyun-Kyung Chung, Cesidio Giuliani, Dinah S. Singer, Leonard D. Kohn, Antonino Grassadonia, Minoru Nakazato, Nicola Tinari, T. Kevin Howcroft, Bruno Fiorentino, Stefano Iacobelli

Publikováno v: Endocrinology. 148:3507-3517

We previously reported that hormones important for the normal growth and function of FRTL-5 rat thyroid cells, TSH, or its cAMP signal plus insulin or IGF-I, could transcriptionally suppress constitutive and γ-interferon (IFN)-increased synthesis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c84c6972d5bf19d6088e83382c00d2
https://doi.org/10.1210/en.2007-0024

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The 90K Protein Increases Major Histocompatibility Complex Class I Expression and Is Regulated by Hormones, γ-Interferon, and Double-Strand Polynucleotides

Autor: Giorgio Napolitano, Dinah S. Singer, Leonard D. Kohn, Stefano Iacobelli, Michele De Tursi, Antonino Grassadonia, Cesidio Giuliani, Bruno Fiorentino, Nicola Tinari, Koichi Suzuki, Minoru Nakazato

Publikováno v: Endocrinology. 145:4728-4736

Here we report the cloning of the rat 90K, a homolog of the mouse cyclophilin C-associated protein/mouse adherent macrophage and human 90K. The protein is constitutively expressed by FRTL-5 thyrocytes, and its levels are modulated by TSH, insulin/IGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb016a0d7918ee786add08c08b32c85
https://doi.org/10.1210/en.2004-0506

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Regulation of Major Histocompatibility Class II Gene Expression in FRTL-5 Thyrocytes: Opposite Effects of Interferon and Methimazole*

Autor: Koichi Suzuki, Dinah S. Singer, Bruno Fiorentino, Cesidio Giuliani, Minho Shong, Andreas M. Reimold, Motoyasu Saji, Valeria Montani, Shin-ichi Taniguchi, Giorgio Napolitano, Leonard D. Kohn, Jun Saito

Publikováno v: Endocrinology. 139:290-302

Aberrant expression of major histocompatibility complex (MHC) class II antigens is associated with autoimmune thyroid disease; aberrant expression duplicating the autoimmune state can be induced by interferon-gamma (IFNgamma). We have studied IFNgamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e21948233148f5748620c7d17134925
https://doi.org/10.1210/endo.139.1.5658

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Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein

Autor: Cesidio Giuliani, Giorgio Napolitano, Valeria Montani, Andreas M. Reimold, Minho Shong, Jenny P.-Y. Ting, Bruno Fiorentino, Motoyasu Saji, Shin-ichi Taniguchi, Dinah S. Singer, Leonard D. Kohn, Masayuki Ohmori, Koichi Suzuki

Publikováno v: Endocrinology. 139:280-289

Aberrant expression of major histocompatibility complex (MHC) class II proteins on thyrocytes, which is associated with autoimmune thyroid disease, is mimicked by gamma-interferon (gamma-IFN). To define elements and factors that regulate class II gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326ff4d6f3a95debdee046aaca449321
https://doi.org/10.1210/endo.139.1.5673

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Lack of prognostic value of immunohistochemical determination of epidermal growth-factor receptors in human prostate-cancer

Autor: P Distefano, Stefano Iacobelli, Nicola Tinari, R. Tenaglia, Clara Natoli, Bruno Fiorentino, Domenico Angelucci, C. Amatetti

Publikováno v: International journal of oncology. 3(5)

We have investigated whether the expression of Epidermal Growth Factor Receptors (EGF-Rc) evaluated by immunohistochemical technique, may influence the prognosis of patients with prostate cancer. EGF-Rc were positive in 20/76 (26.3%) of tumors. There

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b2f7e15aca6d8f22513df93673c089
https://pubmed.ncbi.nlm.nih.gov/21573448

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DNA and S-phase fraction analysis by flow cytometry in prostate cancer. Clinicopathologic implications

Autor: Domenico Angelucci, Stefano Iacobelli, Andrea Zezza, Clara Natoli, Pia Di Stefano, Raffaele Tenaglia, Michele Nicolai, Nicola Tinari, Bruno Fiorentino, Cristina Amatetti

Publikováno v: Cancer. 71:1289-1296

Background. Available prognostic factors for prostate cancer have not been proven consistently useful. The authors evaluated the prognostic value of DNA analysis by flow cytometry (FCM) in prostate cancer. Methods. Paraffin-embedded tumor specimens t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b93920788de3dd49ec168894703e163
https://doi.org/10.1002/1097-0142(19930215)71:4<1289::aid-cncr2820710420>3.0.co

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