Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bruno Doreste"'
Autor:
Irina T. Zaharieva, Mariacristina Scoto, Karolina Aragon‐Gawinska, Deborah Ridout, Bruno Doreste, Laurent Servais, Francesco Muntoni, Haiyan Zhou
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 1011-1026 (2022)
Abstract Objective Spinal muscular atrophy (SMA) is a common genetic cause of infant mortality. Nusinersen treatment ameliorates the clinical outcome of SMA, however, some patients respond well, while others have limited response. We investigated mic
Externí odkaz:
https://doaj.org/article/25ab80b6bfc14c54bc1d6bd5ae1ab5ca
Autor:
Luisa Boldrin, Jacob A. Ross, Charlotte Whitmore, Bruno Doreste, Charlotte Beaver, Ayad Eddaoudi, Daniel J. Pearce, Jennifer E. Morgan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Loss of skeletal muscle mass and function occurs with increasing age. Calorie restriction (CR) increases the lifespan of C57Bl/6 mice, but not in the shorter-lived DBA/2 strain. There is some evidence that calorie restriction reduces or dela
Externí odkaz:
https://doaj.org/article/074cae7fc6c94624a824616992ad4d08
Autor:
Francesco Muntoni, Jennifer E. Morgan, Myra McClure, Jinhong Meng, Nathan P. Sweeney, Bruno Doreste
Publikováno v:
Hum Gene Ther
Stem cell therapy is a promising strategy to treat muscle diseases such as Duchenne muscular dystrophy (DMD). To avoid immune rejection of donor cells or donor-derived muscle, autologous cells, which have been genetically modified to express dystroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba416758cbc1ad327447ab5a0c893048
https://europepmc.org/articles/PMC7047098/
https://europepmc.org/articles/PMC7047098/
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Skeletal muscle stem (satellite) cells transplanted into host mouse muscles contribute to muscle regeneration. Irradiation of host muscle enhances donor stem cell engraftment by promoting the proliferation of transplanted donor cells. We hypothesised