Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bruno Demoro"'
Autor:
Bruno Demoro, Andreia Bento-Oliveira, Fernanda Marques, João Costa Pessoa, Lucía Otero, Dinorah Gambino, Rodrigo F. M. de Almeida, Ana Isabel Tomaz
Publikováno v:
Molecules, Vol 24, Iss 16, p 2861 (2019)
The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite appealing in cancer chemotherapy. This work examined the anticancer activity of an anti-trypa
Externí odkaz:
https://doaj.org/article/da223ba3fd6943a8ba9e673bda17a441
Autor:
Fernanda Marques, Rodrigo F.M. de Almeida, Dinorah Gambino, Andreia Bento-Oliveira, Bruno Demoro, Ana Isabel Tomaz, Lucía Otero, João Costa Pessoa
Publikováno v:
Molecules, Vol 24, Iss 16, p 2861 (2019)
Molecules
Volume 24
Issue 16
Molecules
Volume 24
Issue 16
The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite appealing in cancer chemotherapy. This work examined the anticancer activity of an anti-trypa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a16def19cd8ca9767ab2a54cfc5817
https://www.mdpi.com/1420-3049/24/16/2861
https://www.mdpi.com/1420-3049/24/16/2861
Autor:
Lucía Otero, Dinorah Gambino, Roberto Docampo, Claudio Olea Azar, Santiago Rostán, Julia Torres, Zhu-Hong Li, Juan Diego Maya, Bruno Demoro, Mauricio Moncada
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 23(2)
To face the high costs of developing new drugs, researchers in both industry and academy are looking for ways to repurpose old drugs for new uses. In this sense, bisphosphonates that are clinically used for bone diseases have been studied as agents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7386fdeb7de226c66bca9d0eab11936
https://pubmed.ncbi.nlm.nih.gov/29349663
https://pubmed.ncbi.nlm.nih.gov/29349663
Autor:
Bruno Demoro, Clarice Queico Fujimura Leite, Dinorah Gambino, Ignacio Machado, Gustavo A. Echeverría, Leonardo B. Marino, Oscar E. Piro, Fernando Rogério Pavan
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Universidad Nacional de La Plata
instacron:UNLP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
In the search for new therapeutic tools against tuberculosis and to further address the therapeutic potential of pyridine-2-thiol 1-oxide (Hmpo) metal complexes, two new octahedral [M(III)(mpo)3] complexes, with M = Ga or Bi, were synthesized and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badea7b217f5cf3e5ca66549d5be5dbd
https://doi.org/10.1016/j.ejmech.2014.09.067
https://doi.org/10.1016/j.ejmech.2014.09.067
Autor:
Bruno Demoro, Graciela Mahler, Francesco Caruso, Daniel Liebowitz, Dinorah Gambino, Claudio Olea-Azar, Lucía Otero, Miriam Rossi, Chiara Pizzo, Ulrike Kemmerling, Virtudes Moreno, Helena Guiset, Juan Diego Maya
Publikováno v:
Biological Trace Element Research. 153:371-381
In the search for new metal-based drugs against diseases produced by trypanosomatid parasites, four organoruthenium(II) compounds [Ru2(p-cymene)2(L)2]X2, where L are bioactive 5-nitrofuryl-containing thiosemicarbazones and X = Cl or PF6, had been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95f7b6eacfdf3bef46345663e94176
https://doi.org/10.1007/s12011-013-9653-4
https://doi.org/10.1007/s12011-013-9653-4
Autor:
Cristina P. Matos, Dinorah Gambino, Virtudes Moreno, Ana Isabel Tomaz, Fernanda Marques, Alejandra Rodríguez, Bruno Demoro, Rodrigo F.M. de Almeida, João Costa Pessoa, Isabel Santos, Lucía Otero, Julia Lorenzo
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 42(19)
Four complexes combining the {Ru(p-cym)} moiety (p-cym = para-cymene) with thiosemicarbazone (TSC) ligands containing the 5-nitrofuryl pharmacophore were investigated in vitro for their properties as prospective anti-tumour agents. The compounds are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d7e2ce38c9eeb709744719cffe98b6
https://pubmed.ncbi.nlm.nih.gov/23519281
https://pubmed.ncbi.nlm.nih.gov/23519281
Autor:
Francesco Caruso, Hugo Cerecetto, Dinorah Gambino, Roberto Docampo, Leena Malayil, Alvaro W. Mombrú, Mercedes González, Miriam Rossi, Bruno Demoro, Diego Benítez, Lucía Otero, Melina Galizzi, Ricardo Faccio
Publikováno v:
Dalton transactions (2003. Print) 41 (2012): 6468–6476. doi:10.1039/C2DT12179D
info:cnr-pdr/source/autori:Bruno Demoro, Francesco Caruso, Miriam Rossi, Diego Benítez, Mercedes González, Hugo Cerecetto, Melina Galizzi, Leena Malayil, Roberto Docampo, Ricardo Faccio, Álvaro W. Mombrú, Dinorah Gambino, Lucía Otero/titolo:Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase./doi:10.1039%2FC2DT12179D/rivista:Dalton transactions (2003. Print)/anno:2012/pagina_da:6468/pagina_a:6476/intervallo_pagine:6468–6476/volume:41
info:cnr-pdr/source/autori:Bruno Demoro, Francesco Caruso, Miriam Rossi, Diego Benítez, Mercedes González, Hugo Cerecetto, Melina Galizzi, Leena Malayil, Roberto Docampo, Ricardo Faccio, Álvaro W. Mombrú, Dinorah Gambino, Lucía Otero/titolo:Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase./doi:10.1039%2FC2DT12179D/rivista:Dalton transactions (2003. Print)/anno:2012/pagina_da:6468/pagina_a:6476/intervallo_pagine:6468–6476/volume:41
In the search for a pharmacological answer to treat Chagas disease, eight metal complexes with two bioactive bisphosphonates, alendronate (Ale) and pamidronate (Pam), were described. Complexes of the formula [M(2)(II)(Ale)(4)(H(2)O)(2)]·2H(2)O, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c32859fdfd090778ea862c64156a1c0
https://pubmed.ncbi.nlm.nih.gov/22344249
https://pubmed.ncbi.nlm.nih.gov/22344249
Autor:
Andrea Medeiros, Miriam Rossi, Bruno Demoro, Francesco Caruso, Lucía Otero, Cynthia Sarniguet, Daniel Liebowitz, Roberto A. Sánchez-Delgado, Marcelo A. Comini, Dinorah Gambino, Claudio Olea-Azar, Virtudes Moreno
Publikováno v:
Dalton Transactions
Dalton Transactions, Royal Society of Chemistry, 2012, 41 (5), pp.1534-43. ⟨10.1039/c1dt11519g⟩
Dalton transactions (2003. Online) 41 (2012): 1534–1543. doi:10.1039/c1dt11519g
info:cnr-pdr/source/autori:Bruno Demoro, Cynthia Sarniguet, Roberto Sanchez-Delgado, Miriam Rossi, Daniel Liebowitz, Caruso F, Claudio Olea-Azar, Virtudes Moreno, Andrea Medeiros, Marcelo A. Comini, Luca Otero, Dinorah Gambino/titolo:New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents./doi:10.1039%2Fc1dt11519g/rivista:Dalton transactions (2003. Online)/anno:2012/pagina_da:1534/pagina_a:1543/intervallo_pagine:1534–1543/volume:41
Dalton Transactions, Royal Society of Chemistry, 2012, 41 (5), pp.1534-43. ⟨10.1039/c1dt11519g⟩
Dalton transactions (2003. Online) 41 (2012): 1534–1543. doi:10.1039/c1dt11519g
info:cnr-pdr/source/autori:Bruno Demoro, Cynthia Sarniguet, Roberto Sanchez-Delgado, Miriam Rossi, Daniel Liebowitz, Caruso F, Claudio Olea-Azar, Virtudes Moreno, Andrea Medeiros, Marcelo A. Comini, Luca Otero, Dinorah Gambino/titolo:New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents./doi:10.1039%2Fc1dt11519g/rivista:Dalton transactions (2003. Online)/anno:2012/pagina_da:1534/pagina_a:1543/intervallo_pagine:1534–1543/volume:41
International audience; In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasites, and particularly against African Trypanosomiasis, whose etiological agent is Trypanosoma brucei, organoruthenium compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6952211ec01b0be094cbe669dad6bb0
https://hal-riip.archives-ouvertes.fr/pasteur-00686572
https://hal-riip.archives-ouvertes.fr/pasteur-00686572
Autor:
Mercedes González, Melina Galizzi, Francesco Caruso, Miriam Rossi, Hugo Cerecetto, Dinorah Gambino, Roberto Docampo, Bruno Demoro, Lucía Otero, Diego Benítez, Beatriz S. Parajón-Costa, Jorge Castiglioni
Publikováno v:
Journal of inorganic biochemistry 104 (2010): 1252–1258. doi:10.1016/j.jinorgbio.2010.08.004
info:cnr-pdr/source/autori:Demoro Bruno; Caruso Francesco; Rossi Miriam; Bentez Diego; Gonzalez Mercedes; Cerecetto Hugo; Parajon-Costa Beatriz; Castiglioni Jorge; Galizzi Melina; Docampo Roberto; Otero Luca ; Gambino Dinorah/titolo:Risedronate metal complexes potentially active against Chagas disease/doi:10.1016%2Fj.jinorgbio.2010.08.004/rivista:Journal of inorganic biochemistry/anno:2010/pagina_da:1252/pagina_a:1258/intervallo_pagine:1252–1258/volume:104
info:cnr-pdr/source/autori:Demoro Bruno; Caruso Francesco; Rossi Miriam; Bentez Diego; Gonzalez Mercedes; Cerecetto Hugo; Parajon-Costa Beatriz; Castiglioni Jorge; Galizzi Melina; Docampo Roberto; Otero Luca ; Gambino Dinorah/titolo:Risedronate metal complexes potentially active against Chagas disease/doi:10.1016%2Fj.jinorgbio.2010.08.004/rivista:Journal of inorganic biochemistry/anno:2010/pagina_da:1252/pagina_a:1258/intervallo_pagine:1252–1258/volume:104
In the search for new metal-based drugs for the treatment of Chagas disease, the most widespread Latin American parasitic disease, novel complexes of the bioactive ligand risedronate (Ris, (1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonate), [MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a013761c7341d9a7ad42ad35fc65f26
https://pubmed.ncbi.nlm.nih.gov/20817265
https://pubmed.ncbi.nlm.nih.gov/20817265
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 65:s287-s287
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ea8a704f586e44656b348060c9ae4b
https://doi.org/10.1107/s010876730909391x
https://doi.org/10.1107/s010876730909391x