Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bruno Christian Koehler"'
Autor:
Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Christin Elssner, Nicole Kautz, Stefan Welte, Dirk Jaeger, Toni Urbanik, Henning Schulze-Bergkamen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106571 (2014)
Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising ant
Externí odkaz:
https://doaj.org/article/1f352e97a5ad487eb17326b147b8c202
Autor:
Stefan Welte, Toni Urbanik, Christin Elßner, Nicole Kautz, Bruno Christian Koehler, Nina Waldburger, Justo Lorenzo Bermejo, Federico Pinna, Karl-Heinz Weiss, Peter Schemmer, Dirk Jaeger, Thomas Longerich, Kai Breuhahn, Henning Schulze-Bergkamen
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110591 (2014)
The deubiquitinase CYLD removes (K-63)-linked polyubiquitin chains from proteins involved in NF-κB, Wnt/ß-catenin and Bcl-3 signaling. Reduced CYLD expression has been reported in different tumor entities, including hepatocellular carcinoma (HCC).
Externí odkaz:
https://doaj.org/article/41fea40eb7b94ea1b8ccf09c1676dd8b
Autor:
Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Toni Urbanik, Nicole Kautz, Christin Elssner, Stefan Welte, Justo Lorenzo Bermejo, Dirk Jäger, Henning Schulze-Bergkamen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76446 (2013)
Migration and invasion of malignant cells are prerequisites for cancer progression and metastasis. The Bcl-2 family of proteins consists of about 25 members and has been extensively studied in the context of apoptosis. Despite the fact that small mol
Externí odkaz:
https://doaj.org/article/a0299ed43f1f454c8794e21ee835a2df
Autor:
Barbara Gruen, Constantin Pixberg, Jakob Nikolas Kather, Hans Martin Singh, Editha Gnutzmann, Mareike Dietrich, Bruno Christian Koehler, Niels Steinebrunner, Helen Starke, Andreas Mock, Andreas Schneeweiss, Eva C. Winkler, Lena Woydack, Athanasios Mavratzas, Helene Hofmann, Erkin Erdal, David Schult, Johannes Krisam, Leon Muehlsteffen, Felix Korell, Thomas Walle, Alexandra Ivanova, Dirk Jaeger
BackgroundMobile phone video call applications generally did not undergo testing in randomized controlled clinical trials prior to their implementation in patient care regarding the rate of successful patient visits and impact on the physician-patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72324514b039cab5a14e157deaa4cbdb
https://doi.org/10.1101/2020.07.10.20150052
https://doi.org/10.1101/2020.07.10.20150052
Autor:
Viktoria Schuetz, Dogu Teber, M. Hatzinger, Fabian Stoegbauer, Christoph Springfeld, Bruno Christian Koehler, Albrecht Stenzinger, Yakup Kulu, Joanne Nyarangi-Dix, Markus Hohenfellner, Jan Philipp Radtke, Georgi Tosev
Publikováno v:
Urology Case Reports
Background: Common tumor metastasis sites for intrahepatic cholangiocarcinoma (ICC) include regional lymph nodes as well as liver metastasis as an indication of tumor recurrence. The main route for the spread of tumor cells is generally via lymph ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2fce6bacf23aa51695c1e1a328cdcc
https://doi.org/10.35841/cancer-research.1.1.8-11
https://doi.org/10.35841/cancer-research.1.1.8-11
Autor:
Thomas Bruckner, Tatjana Arslic-Schmitt, Henning Schulze-Bergkamen, Georg Gdynia, Theresa Peccerella, Sebastian Mueller, Dirk Jäger, Bruno Christian Koehler, Helmut K. Seitz, Helmut Bartsch, Anna-Lena Scherr
Publikováno v:
Alcoholism, clinical and experimental research. 40(10)
Background Chronic alcohol consumption is a risk factor for colorectal cancer. The mechanisms by which ethanol (EtOH) exerts its carcinogenic effect on the colorectal mucosa are not clear and may include oxidative stress with the action of reactive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edd7ca1baeb9df196a11d62aa665a0a
https://pubmed.ncbi.nlm.nih.gov/27581253
https://pubmed.ncbi.nlm.nih.gov/27581253
Autor:
Henning Schulze-Bergkamen, Georg Gdynia, Wilfried Roth, Martin Schneider, Mariam Salou, You-Wen He, Achim Weber, Praveen Radhakrishnan, Adam Jassowicz, Christin Elssner, Dirk Jaeger, Nicole Kautz, Bruno Christian Koehler, Sophia Keim, Katarina Duglova, Anette Heller, Mathias Heikenwalder, Anna Lena Scherr
Publikováno v:
Cell Death & Disease
Cell Death Dis. 7:e2342 (2016)
Cell Death Dis. 7:e2342 (2016)
Colorectal cancer (CRC) is the second most common malignant neoplasia in women and men worldwide. The B-cell lymphoma 2 (Bcl-2) protein family is mainly known for its pivotal role in the regulation of the mitochondrial death pathway. Anti-apoptotic B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3f61b83847b959e2a50e56ba9048f9
https://www.zora.uzh.ch/id/eprint/125660/
https://www.zora.uzh.ch/id/eprint/125660/
Autor:
Lisa Katharina Platzer, Bruno Christian Koehler, Anna-Lena Scherr, Henning Schulze-Bergkamen, Jonathan M. Harnoss, Klaus Podar, Judit Kiss, Nadine Ruh, Thomas Schmidt, Juergen Weitz, Martin Mollenhauer, Alexis Ulrich, Joseph T. Opferman, Praveenkumar Radhakrishnan, Martin Schneider
Publikováno v:
Cancer research. 76(8)
Hypoxia is a common feature of solid tumors. Prolyl hydroxylase enzymes (PHD1–3) are molecular oxygen sensors that regulate hypoxia-inducible factor activity, but their functions in metastatic disease remain unclear. Here, we assessed the significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7b10817ab283e8797a25b1a057ec10
https://pubmed.ncbi.nlm.nih.gov/26921340
https://pubmed.ncbi.nlm.nih.gov/26921340
Autor:
Bruno Christian Koehler, Laura E Wolpert, Christin Elßner, Dirk Jäger, Ari Waisman, Henning Schulze-Bergkamen, T Urbanik, Stefan Ezechiel Welte, Thomas Longerich, Nicole Kautz, Nadine Hövelmeyer, Anna-Lena Scherr
Publikováno v:
World journal of gastroenterology. 20(45)
AIM: To analyze the role of CYLD for receptor-mediated cell death of murine hepatocytes in acute liver injury models. METHODS: Hepatocyte cell death in CYLD knockout mice (CYLD-/-) was analyzed by application of liver injury models for CD95- (Jo2) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be88b0ca8ca62934c95a4369d1e3bf7
https://pubmed.ncbi.nlm.nih.gov/25493017
https://pubmed.ncbi.nlm.nih.gov/25493017
Autor:
Henning Schulze-Bergkamen, Nicole Kautz, Stephan Lorenz, Bruno Christian Koehler, Toni Urbanik, Dirk Jaeger, Christin Elssner, Anna-Lena Scherr, Stefan Ezechiel Welte
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106571 (2014)
PLoS ONE
PLoS ONE
Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e314cced9a53b7d7f862e951a7dc419
http://europepmc.org/articles/PMC4156353?pdf=render
http://europepmc.org/articles/PMC4156353?pdf=render