Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Bruno Chatton"'
Publikováno v:
Cells, Vol 12, Iss 12, p 1591 (2023)
Transient transfection of foreign DNA is the most widely used laboratory technique to study gene function and product. However, the transfection efficiency depends on many parameters, including DNA quantity and quality, transfection methods and targe
Externí odkaz:
https://doaj.org/article/915779c4b3b540e4918aadb434729815
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14405 (2022)
The homogeneous labeling of antibodies and their fragments is a critical step for the generation of robust probes used in immuno-detection applications. To date, numerous chemical, genetic and peptide-based site-specific coupling methods have been de
Externí odkaz:
https://doaj.org/article/efa17e75b42e4cc0bd4aed09c2f2ad53
Publikováno v:
iScience, Vol 13, Iss , Pp 98-112 (2019)
Summary: Adipocytes function as major players in the regulation of metabolic homeostasis, and factors contributing to adipocyte differentiation and function are promising targets for combatting obesity and associated metabolic disorders. Activating t
Externí odkaz:
https://doaj.org/article/321402508407497083b9f43028d65f89
Autor:
Frank Dietsch, Mariel Donzeau, Agnes M. Cordonnier, Etienne Weiss, Bruno Chatton, Marc Vigneron
Publikováno v:
BioTechniques, Vol 62, Iss 2, Pp 80-82 (2017)
Here we developed a complementation method for the study of essential genes in live human cells using the CRISPR/Cas9 system. Proteins encoded by essential genes were expressed using a derivative of the pCEP4 compensating plasmid in combination with
Externí odkaz:
https://doaj.org/article/6000367f29af48ed897405277b94e259
Autor:
Jessica Diring, Barbara Camuzeaux, Mariel Donzeau, Marc Vigneron, Manuel Rosa-Calatrava, Claude Kedinger, Bruno Chatton
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23351 (2011)
Alternative splicing and post-translational modifications are processes that give rise to the complexity of the proteome. The nuclear ATF7 and ATF2 (activating transcription factor) are structurally homologous leucine zipper transcription factors enc
Externí odkaz:
https://doaj.org/article/301b236aaa2843649bbfc83a0a7890f4
Autor:
Camille Kostmann, Mariel Donzeau, Anna Bonhoure, Frank Dietsch, Yves Nominé, Audrey Stoessel, Bruno Chatton
Publikováno v:
Journal of Immunological Methods
Journal of Immunological Methods, Elsevier, 2021, 498, pp.113144. ⟨10.1016/j.jim.2021.113144⟩
Journal of Immunological Methods, 2021, 498, pp.113144. ⟨10.1016/j.jim.2021.113144⟩
Journal of Immunological Methods, Elsevier, 2021, 498, pp.113144. ⟨10.1016/j.jim.2021.113144⟩
Journal of Immunological Methods, 2021, 498, pp.113144. ⟨10.1016/j.jim.2021.113144⟩
Bivalent VHHs have been shown to display better functional affinity compared with their monovalent counterparts. Bivalency can be achieved either by inserting a hinge region between both VHHs units or by using modules that lead to dimerization. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3260a2bebc454c45137d364631f046
https://hal.archives-ouvertes.fr/hal-03370331/document
https://hal.archives-ouvertes.fr/hal-03370331/document
Autor:
Yang Liu, Toshio Maekawa, Masafumi Muratani, Shunsuke Ishii, Binbin Liu, Keisuke Yoshida, Bruno Chatton
Publikováno v:
Genes to Cells. 24:627-635
Cellular senescence plays an important role in aging and is induced by cyclin-dependent kinase (Cdk) inhibitors that accumulate following stresses during aging. However, the underlying mechanism remains elusive. Herein, we demonstrate that activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4631c6dfc11fdb0fbfbeff42f8522a
https://doi.org/10.1111/gtc.12713
https://doi.org/10.1111/gtc.12713
Autor:
Agnès M. Cordonnier, Mariel Donzeau, Yves Nominé, Annick Dejaegere, Bruno Chatton, Frank Dietsch, Marc Vigneron, Guy Zuber, Laurent Bianchetti
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, 2019, 30 (6), pp.1734-1744. ⟨10.1021/acs.bioconjchem.9b00276⟩
Bioconjugate Chemistry, 2019, 30 (6), pp.1734-1744. ⟨10.1021/acs.bioconjchem.9b00276⟩
Monitoring the assembly of macromolecules to design entities with novel properties can be achieved either chemically creating covalent bonds or by noncovalent connections using appropriate structural motifs. In this report, two self-associating pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16da2632911f6dbb7df3bbe01a03c70b
https://doi.org/10.1021/acs.bioconjchem.9b00276
https://doi.org/10.1021/acs.bioconjchem.9b00276
Autor:
Mariel Donzeau, Celia Deville, Yves Nominé, Nikita Pallaoro, Lina Barret, Bruno Chatton, Marie Blocat, Ambre Bender, Audrey Stoessel, Lucile Guyot, Leonel Nguekeu-Zebaze, Guy Zuber, Nadja Groysbeck, Laetitia Voilquin, Murielle Masson, Thomas Lutz
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2020, 31 (10), pp.2421-2430. ⟨10.1021/acs.bioconjchem.0c00482⟩
Bioconjugate Chemistry, American Chemical Society, 2020, 31 (10), pp.2421-2430. ⟨10.1021/acs.bioconjchem.0c00482⟩
Immunotoxins are emerging candidates for cancer therapeutics. These biomolecules consist of a cell-targeting protein combined to a polypeptide toxin. Associations of both entities can be achieved either chemically by covalent bonds or genetically cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f2c9a574f7317a827404a0d150ea01
https://hal.archives-ouvertes.fr/hal-03005245
https://hal.archives-ouvertes.fr/hal-03005245
Autor:
Keisuke Yoshida, Kimiko Inoue, Bruno Chatton, Nhung Hong Ly, Ayumi Hasegawa, Atsuo Ogura, Shunsuke Ishii, Toshio Maekawa, Binbin Liu
Publikováno v:
Nucleic Acids Research
Various stresses increase disease susceptibility and accelerate aging, and increasing evidence suggests that these effects can be transmitted over generation. Epidemiological studies suggest that stressors experienced by parents affect the longevity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7419ccc8b74c4d79d33bdc7ba6eeafcc
https://doi.org/10.1093/nar/gky1149
https://doi.org/10.1093/nar/gky1149