Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bruno Cavadas"'
Autor:
Liliana Oliveira, M. Carolina Silva, Ana P. Gomes, Rita F. Santos, Marcos S. Cardoso, Ana Nóvoa, Hervé Luche, Bruno Cavadas, Irina Amorim, Fátima Gärtner, Bernard Malissen, Moisés Mallo, Alexandre M. Carmo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sepsis results from systemic, dysregulated inflammatory responses to infection, culminating in multiple organ failure. Here, we demonstrate the utility of CD5L for treating experimental sepsis caused by cecal ligation and puncture (CLP). We
Externí odkaz:
https://doaj.org/article/b069eaf5d01f4fed8e7e71994fabe4ac
Autor:
Bárbara Adem, Nuno Bastos, Carolina F. Ruivo, Sara Sousa-Alves, Carolina Dias, Patrícia F. Vieira, Inês A. Batista, Bruno Cavadas, Dieter Saur, José C. Machado, Dawen Cai, Sonia A. Melo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the genetically engineered mouse model (
Externí odkaz:
https://doaj.org/article/bc7d9ee1ccd04333abccf2b19c10a836
Autor:
Laura Mosteo, Lidia Rocha, Ana Raquel Maceiras, Bruno Cavadas, Carolina Pereira, Marta Lopes, Sérgio Chacim, Inês Ramos, Edwin Hawkins, José Mário Mariz, Graça Porto, Delfim Duarte
Publikováno v:
HemaSphere, Vol 7, p e21173fa (2023)
Externí odkaz:
https://doaj.org/article/111ba0e59bda494cb1c3008aa318e62d
NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features
Autor:
Catarina Tavares, Maria João Coelho, Catarina Eloy, Miguel Melo, Adriana Gaspar da Rocha, Ana Pestana, Rui Batista, Luciana Bueno Ferreira, Elisabete Rios, Samia Selmi-Ruby, Bruno Cavadas, Luísa Pereira, Manuel Sobrinho Simões, Paula Soares
Publikováno v:
Endocrine Connections, Vol 7, Iss 1, Pp 78-90 (2018)
Thyroid cancer therapy is based on surgery followed by radioiodine treatment. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS) (codified by the SLC5A5 gene), that is functional only when targeted to the
Externí odkaz:
https://doaj.org/article/4d9954806eb6413497b275b7374e99cd
Autor:
Ricardo Celestino, Torfinn Nome, Ana Pestana, Andreas M. Hoff, A. Pedro Gonçalves, Luísa Pereira, Bruno Cavadas, Catarina Eloy, Trine Bjøro, Manuel Sobrinho-Simões, Rolf I. Skotheim, Paula Soares
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-16 (2018)
Abstract Background The prognostic variability of thyroid carcinomas has led to the search for accurate biomarkers at the molecular level. Follicular thyroid carcinoma (FTC) is a typical example of differentiated thyroid carcinomas (DTC) in which cha
Externí odkaz:
https://doaj.org/article/dd729bd9c29d4a62a4f57b9b60fc72e1
Autor:
Beatriz Sierra, Ana Cristina Magalhães, Daniel Soares, Bruno Cavadas, Ana B. Perez, Mayling Alvarez, Eglis Aguirre, Claudia Bracho, Luisa Pereira, Maria G. Guzman
Publikováno v:
Viruses, Vol 13, Iss 8, p 1540 (2021)
Transcriptomics, proteomics and pathogen-host interactomics data are being explored for the in silico–informed selection of drugs, prior to their functional evaluation. The effectiveness of this kind of strategy has been put to the test in the curr
Externí odkaz:
https://doaj.org/article/ac68158c0bb04d00a9ce010e7d0a727b
Autor:
Nicole Pedro, Veronica Fernandes, Bruno Cavadas, João Tiago Guimarães, Henrique Barros, Margarida Tavares, Luisa Pereira
Publikováno v:
Viruses, Vol 13, Iss 6, p 1116 (2021)
Field epidemiology and viral sequencing provide a comprehensive characterization of transmission chains and allow a better identification of superspreading events. However, very few examples have been presented to date during the COVID-19 pandemic. W
Externí odkaz:
https://doaj.org/article/7f5957152e0242fd907878c7dc7bed06
Autor:
Miguel Sardinha Marques, Joana Melo, Bruno Cavadas, Nuno Mendes, Luísa Pereira, Fátima Carneiro, Ceu Figueiredo, Marina Leite
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Afadin is a cytoplasmic protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight junctions. Aberrant expression of Afadin has been shown in cancer and its loss has been associated with epit
Externí odkaz:
https://doaj.org/article/f2f4a4567f634004a23a98f1b01ea94d
Autor:
Nicole Pedro, Cláudio N. Silva, Ana C. Magalhães, Bruno Cavadas, Ana M. Rocha, Ana C. Moreira, Maria Salomé Gomes, Diogo Silva, Joana Sobrinho-Simões, Angélica Ramos, Maria J. Cardoso, Rita Filipe, Pedro Palma, Filipa Ceia, Susana Silva, João T. Guimarães, António Sarmento, Verónica Fernandes, Luisa Pereira, Margarida Tavares
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 300 (2021)
A few molecularly proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases of symptomatic reinfection are currently known worldwide, with a resolved first infection followed by a second infection after a 48 to 142-day intervening per
Externí odkaz:
https://doaj.org/article/7897bf38792d4735af78c65ff2c571fa
Autor:
Bruno Cavadas, Marina Leite, Nicole Pedro, Ana C. Magalhães, Joana Melo, Marcelo Correia, Valdemar Máximo, Rui Camacho, Nuno A. Fonseca, Ceu Figueiredo, Luísa Pereira
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 240 (2021)
The continuous characterization of genome-wide diversity in population and case–cohort samples, allied to the development of new algorithms, are shedding light on host ancestry impact and selection events on various infectious diseases. Especially
Externí odkaz:
https://doaj.org/article/ae85ab9227f24a5aa0459e79d3a47421