Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Bruno C. Medeiros"'
Autor:
Laurène Pousse, Koorosh Korfi, Bruno C. Medeiros, Marco Berrera, Nadine Kumpesa, Jan Eckmann, Idil Karakoc Hutter, Vera Griesser, Vaios Karanikas, Christian Klein, Maria Amann
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAcute Myeloid leukemia is a heterogeneous disease that requires novel targeted treatment options tailored to the patients’ specific microenvironment and blast phenotype.MethodsWe characterized bone marrow and/or blood samples of 37 AML pa
Externí odkaz:
https://doaj.org/article/26b1cfeae8be48eea4e271097d31fc49
Autor:
L. Elise Horvath Walsh, Alex Rider, James Piercy, James Pike, Samuel Wilson, Bhavik J. Pandya, Bruno C. Medeiros
Publikováno v:
Oncology and Therapy, Vol 7, Iss 1, Pp 67-81 (2019)
Abstract Introduction There is limited understanding concerning the health-related quality of life (HRQoL) in acute myeloid leukemia (AML) patients. Due to an overlap of symptoms, it can be difficult to separate disease versus treatment-related effec
Externí odkaz:
https://doaj.org/article/21006648048c4562843b2441416832e6
Autor:
Iris Amitay-Laish, MD, Uma Sundram, MD, PhD, Richard T. Hoppe, MD, Emmilia Hodak, MD, Bruno C. Medeiros, MD, Youn H. Kim, MD
Publikováno v:
JAAD Case Reports, Vol 3, Iss 4, Pp 310-315 (2017)
Externí odkaz:
https://doaj.org/article/fb55bfc6e22842e18503021b5c770d53
Autor:
Alyssa Carey, David K. Edwards, V, Christopher A. Eide, Laura Newell, Elie Traer, Bruno C. Medeiros, Daniel A. Pollyea, Michael W. Deininger, Robert H. Collins, Jeffrey W. Tyner, Brian J. Druker, Grover C. Bagby, Shannon K. McWeeney, Anupriya Agarwal
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3204-3218 (2017)
Secreted proteins in the bone marrow microenvironment play critical roles in acute myeloid leukemia (AML). Through an ex vivo functional screen of 94 cytokines, we identified that the pro-inflammatory cytokine interleukin-1 (IL-1) elicited profound e
Externí odkaz:
https://doaj.org/article/381cf8ee8bde4d07ae49773000f6b9fe
Publikováno v:
HemaSphere, Vol 2, Pp 153-155 (2018)
Externí odkaz:
https://doaj.org/article/161f626a27d04a0c8907725d89e109b6
Autor:
Roland B. Walter, Megan Othus, Kaysey F. Orlowski, Emily N. McDaniel, Bart L. Scott, Pamela S. Becker, Mary-Elizabeth M. Percival, Paul C. Hendrie, Bruno C. Medeiros, Michael T. Chiarella, Arthur C. Louie, Elihu H. Estey
Publikováno v:
Haematologica, Vol 103, Iss 3 (2018)
Externí odkaz:
https://doaj.org/article/b050983645dc49d4893f684b474b0d2c
Autor:
Bruno C. Medeiros, Kelly McCaul, Suman Kambhampati, Daniel A. Pollyea, Rajat Kumar, Lewis R. Silverman, Andrea Kew, Lalit Saini, CL Beach, Ravi Vij, Xiwei Wang, Jim Zhong, Robert Peter Gale
Publikováno v:
Haematologica, Vol 103, Iss 1 (2018)
Therapy of acute myeloid leukemia in older persons is associated with poor outcomes because of intolerance to intensive therapy, resistant disease and co-morbidities. This multi-center, randomized, open-label, phase II trial compared safety and effic
Externí odkaz:
https://doaj.org/article/996424bd79e3482db71368b705848b5c
Autor:
Bruno C. Medeiros
Publikováno v:
Haematologica, Vol 102, Iss 8 (2017)
Externí odkaz:
https://doaj.org/article/5cef8af1736742ee8adf12b6b4cd4ab0
Publikováno v:
Haematologica, Vol 100, Iss 3 (2015)
Clonal heterogeneity is a hallmark of malignant transformation. In acute myeloid leukemia, acquired cytogenetic abnormalities are important independent predictors of initial response to therapy, remission duration, and overall survival. However, whet
Externí odkaz:
https://doaj.org/article/aeca16b964734e7db64b7c1195508c47
Autor:
Roland B. Walter, Bruno C. Medeiros, Kelda M. Gardner, Kaysey F. Orlowski, Leonel Gallegos, Bart L. Scott, Paul C. Hendrie, Elihu H. Estey
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
Epigenetic therapeutics such as the histone deacetylase inhibitor, vorinostat, and the DNA methyltransferase I inhibitor, azacitidine, enhance gemtuzumab ozogamicin efficacy in vitro. We therefore investigated vorinostat/azacitidine/gemtuzumab ozogam
Externí odkaz:
https://doaj.org/article/a48e037ac1f5450fa9441987e9993b83