Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bruno Borguesan"'
Publikováno v:
Journal of computational biology, 25 (4), 451-465
In many structural bioinformatics problems, there is a broad range of unanswered questions about protein dynamics and amino acid properties. Proteins are not strictly static objects, but rather populate ensembles of conformations. One way to understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55f41dea8d495285f6a3d15427b14de
https://doi.org/10.1089/cmb.2017.0182
https://doi.org/10.1089/cmb.2017.0182
Publikováno v:
Computers & operations research, 91, 160-177
Tertiary protein structure prediction is a challenging problem in Structural Bioinformatics and is classified according to the computational complexity theory as a NP-hard problem. In this paper, we proposed a first-principle method that makes use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22873fe57c093fcaee7f95356d40f9b3
https://doi.org/10.1016/j.cor.2017.11.015
https://doi.org/10.1016/j.cor.2017.11.015
Autor:
Márcio Dorn, Mario Inostroza-Ponta, Bruno Iochins Grisci, Bruno Borguesan, Mariel Barbachan e Silva
Publikováno v:
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
CONICYT Chile
instacron:CONICYT
Tertiary protein structure prediction is one of the most challenging problems in structural bioinformatics. Despite the advances in algorithm development and computational strategies, predicting the folded structure of a protein only from its amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4d830fe4591684d4fbef79cf95b352
https://doi.org/10.1016/j.compbiolchem.2015.08.006
https://doi.org/10.1016/j.compbiolchem.2015.08.006
Publikováno v:
CEC
The knowledge about the conformation of a protein molecule allows the inference and study of its biological function. Because protein function is determined by its shape and the physio-chemical properties of its exposed surface, it is extremely impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d846460c2394cea1fb2f9488dd8991
https://doi.org/10.1109/cec.2017.7969429
https://doi.org/10.1109/cec.2017.7969429
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics. 15(3)
Memetic Algorithms are population-based metaheuristics intrinsically concerned with exploiting all available knowledge about the problem under study. The incorporation of problem domain knowledge is not an optional mechanism, but a fundamental featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8cc0f3f58d50f3d4cfd52abde4b230
https://pubmed.ncbi.nlm.nih.gov/28029627
https://pubmed.ncbi.nlm.nih.gov/28029627
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology. 24(3)
The exponential growth in the number of experimentally determined three-dimensional protein structures provide a new and relevant knowledge about the conformation of amino acids in proteins. Only a few of probability densities of amino acids are publ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5daf61a407f06fff0a31415136840e
https://pubmed.ncbi.nlm.nih.gov/27494258
https://pubmed.ncbi.nlm.nih.gov/27494258
Autor:
Leonardo de Lima Corrêa, Jonas da Silveira Bohrer, Mariel Barbachan e Silva, Bruno Borguesan, Márcio Dorn
Publikováno v:
CEC
The study of proteins and the prediction of their three-dimensional (3-D) structure is one of the most challenging problems in Structural Bioinformatics. Over the last years, several computational strategies have been proposed as a solution to this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de2fc57ff85884acb88cd2151ba6bcb
https://doi.org/10.1109/cec.2016.7743772
https://doi.org/10.1109/cec.2016.7743772