Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bruno Bienfait"'
Autor:
Mengjin Liu, Bruno Bienfait, Oliver Sacher, Johann Gasteiger, Roland J Siezen, Arjen Nauta, Jan M W Geurts
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84769 (2014)
The incompleteness of genome-scale metabolic models is a major bottleneck for systems biology approaches, which are based on large numbers of metabolites as identified and quantified by metabolomics. Many of the revealed secondary metabolites and/or
Externí odkaz:
https://doaj.org/article/5a4162786ca7438eace1a54b81d82641
Autor:
Ann M. Richard, Ryan Lougee, Matthew Adams, Hannah Hidle, Chihae Yang, James Rathman, Tomasz Magdziarz, Bruno Bienfait, Antony J. Williams, Grace Patlewicz
Publikováno v:
Chemical Research in Toxicology. 36:508-534
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3e2eee2e2a73aef0d31269ed0fd5ead
https://doi.org/10.1021/acs.chemrestox.2c00403
https://doi.org/10.1021/acs.chemrestox.2c00403
Autor:
Chihae Yang, James F Rathman, Bruno Bienfait, Matthew Burbank, Ann Detroyer, Steven J. Enoch, James W. Firman, Steve Gutsell, Nicola J. Hewitt, Bryan Hobocienski, Gerry Kenna, Judith C. Madden, Tomasz Magdziarz, Jörg Marusczyk, Aleksandra Mostrag-Szlichtyng, Christopher-Tilman Krueger, Cathy Lester, Catherine Mahoney, Abdulkarim Najjar, Gladys Ouedraogo, Katarzyna R. Przybylak, J. Vinicius Ribeiro, Mark T.D. Cronin
Publikováno v:
Computational Toxicology. 26:100272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5741cc1baeed6bd50fa239de98753095
https://doi.org/10.1016/j.comtox.2023.100272
https://doi.org/10.1016/j.comtox.2023.100272
Autor:
James, Rathman, Chihae, Yang, J Vinicius, Ribeiro, Aleksandra, Mostrag, Shraddha, Thakkar, Weida, Tong, Bryan, Hobocienski, Oliver, Sacher, Tomasz, Magdziarz, Bruno, Bienfait
Publikováno v:
Chemical research in toxicology. 34(2)
Drug-induced liver injury (DILI) remains a challenge when translating knowledge from the preclinical stage to human use cases. Attempts to model human DILI directly based on the information from drug labels have had some success; however, the approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2511b9a51e509f90793acb7aab8eaf6
https://pubmed.ncbi.nlm.nih.gov/33356149
https://pubmed.ncbi.nlm.nih.gov/33356149
Autor:
Oliver Sacher, Jie Liu, Bruno Bienfait, Thomas Magdziarz, Aleksandra Mostraq, James F. Rathman, Thomas Kleinoeder, Aleksey Tarkhov, Chihae Yang, Darshan Mehta, Christof H. Schwab, Joerg Marusczyk
Publikováno v:
Applied Chemoinformatics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b3613f038e32bec7c4895a32a1f69d
https://doi.org/10.1002/9783527806539.ch8
https://doi.org/10.1002/9783527806539.ch8
Autor:
Bruno Bienfait, Oliver Sacher, Aleksey Tarkhov, Johannes Schwoebel, Lothar Terfloth, Ann M. Richard, Tomasz Magdziarz, Chihae Yang, Christof H. Schwab, J. Marusczyk, James F. Rathman, Thomas Kleinoeder, Kirk Arvidson, Johann Gasteiger, Andrew Worth
Publikováno v:
Journal of Chemical Information and Modeling. 55:510-528
Chemotypes are a new approach for representing molecules, chemical substructures and patterns, reaction rules, and reactions. Chemotypes are capable of integrating types of information beyond what is possible using current representation methods (e.g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a95519d6bb3d65a0012091a00cfd8ca
https://doi.org/10.1021/ci500667v
https://doi.org/10.1021/ci500667v
Autor:
Thomas Kleinoeder, J. Park, Oliver Sacher, Aleksey Tarkhov, Aleksandra Mostrag, Tomasz Magdziarz, Chihae Yang, Bruno Bienfait, Elena Fioravanzo, Mark T. D. Cronin, J. Marusczyk, Christof H. Schwab, Jie Liu, M. Gatnik, M. Mulcahy, James F. Rathman
Publikováno v:
Toxicology Letters. 295:S104-S105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adaab9d636eeef408c31f834dba2d540
https://doi.org/10.1016/j.toxlet.2018.06.619
https://doi.org/10.1016/j.toxlet.2018.06.619
Autor:
Aleksandra Mostrag, Bruno Bienfait, Joerg Marusczyk, Oliver Sacher, Simona Kovarich, Christof H. Schwab, Chihae Yang, Lidia Ceriani, Manuela Pavan, Elena Fioravanzo, Thomas Kleinoeder, James F. Rathman, Aleksey Tarkhov
Publikováno v:
Toxicology Letters. 280:S285-S286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0130e28a95770c1ae132aa66a17d1fdf
https://doi.org/10.1016/j.toxlet.2017.07.800
https://doi.org/10.1016/j.toxlet.2017.07.800
Autor:
Bruno Bienfait, Judith C. Madden, Mark T. D. Cronin, Aleksandra Mostrag-Szlichtyng, Chihae Yang, Steven J. Enoch, James W. Firman, Vessela Vitcheva, D.J. Ebbrell, James F. Rathman
Publikováno v:
Toxicology Letters. 295:S101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3de09777a94e87c79c891391bb969978
https://doi.org/10.1016/j.toxlet.2018.06.610
https://doi.org/10.1016/j.toxlet.2018.06.610
Autor:
Victor E. Marquez, Peter M. Blumberg, Jeewoo Lee, Samira Benzaria, George W. A. Milne, Bruno Bienfait, Ravij Sharma, Shaomeng Wang, Kassoum Nacro, Kelly Teng, Nancy E. Lewin
Publikováno v:
Pharmacology & Therapeutics. 82:251-261
The pharmacophore-guided approach used in the first phase of the design of novel protein kinase C (PKC) ligands was based on the study of the geometry of bioequivalent pharmacophores present in diacylglycerol (DAG) and in the more potent phorbol este
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac079f96653bd653e4e95c9d648c97f
https://doi.org/10.1016/s0163-7258(98)00048-5
https://doi.org/10.1016/s0163-7258(98)00048-5