Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Bruno Almeida Lopes"'
Autor:
Viviane Lamim Lovatel, Luize Otero, Ercole Pietro Orlando, Claudia Diniz, Filipe Vicente dos Santos-Bueno, Bruno Almeida Lopes, Elaiza Almeida Antônio de Kós, Monica Kopischitz Praxedes Lusis, Eliana Abdelhay, Teresa de Souza Fernandez
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 14, Iss 1 (2022)
hematopoietic clonal neoplasms. MDS occurs mainly in elderly patients. KMT2A rearrangements (KMT2A-r) are rare in MDS, so little is known about their prognostic value. The present study describes the clinical characteristics of a young adult patient
Externí odkaz:
https://doaj.org/article/78e7499fb0a4444f9fffd78d49e84b45
Autor:
Thayana Conceição Barbosa, Bruno Almeida Lopes, Caroline Barbieri Blunck, Marcela Braga Mansur, Adriana Vanessa Santini Deyl, Mariana Emerenciano, Maria S. Pombo-de-Oliveira
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Background Chromosome translocations are a hallmark of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Additional genomic aberrations are also crucial in both BCP-ALL leukemogenesis and treatment management. Herein, we report the ph
Externí odkaz:
https://doaj.org/article/5637d776a0e64fc4a453818966d8273c
Autor:
Bruno Almeida Lopes, Mariana Emerenciano, Bruno Alves Aguiar Gonçalves, Tállita Meciany Vieira, Ana Rossini, Maria S Pombo-de-Oliveira
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127308 (2015)
Based on observational studies, early age leukemia (EAL) was associated with maternal hormone exposure during pregnancy. We studied the association between genetic polymorphisms of estrogen metabolism and EAL. Using data from the Brazilian Collaborat
Externí odkaz:
https://doaj.org/article/7d80b417e1cf4b5bb308478fa93aa65d
Autor:
Teresa Cristina Cardoso Fonseca, Patrizia Larghero, Regiana Quinto de Souza, Lisandro Ribeiro, Carmen Bonfim, Francianne Gomes Andrade, Ingrid Sardou-Cezar, Teresa de Souza Fernandez, Bruno Almeida Lopes, Maria S. Pombo-de-Oliveira, Gisele Loth, Rolf Marschalek, Claus Meyer, Elissa Santos Morgado
Publikováno v:
Cancer Genetics. :86-90
Therapy-related acute myeloid leukemia (t-AML) following treatment with topoisomerase-II inhibitors has been increasingly reported. These compounds (e.g. etoposide) promote DNA damage and are associated with KMT2A rearrangements. They are widely used
Autor:
CE Teixeira, Hélène Cavé, Mariana Emerenciano, M Boroni, CP Poubel, Christian Meyer, Bruno Almeida Lopes, Rolf Marschalek, Aurélie Caye-Eude
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss, Pp S181-(2021)
Introduction KMT2A (MLL) gene rearrangements (KMT2A -r) are associated with diverse acute leukemias. Given the high number of KMT2A fusions, screening methods guide their detection regardless of partner gene. For instance, immunophenotyping using an
Autor:
Grazia Fazio, Maria S. Pombo-de-Oliveira, Seung Hwan Oh, Ingo Ebersberger, Seong Lin Khaw, Jan Zuna, Hansen J. Kosasih, Renate Panzer Grümayer, Rosemary Sutton, Chloé Arfeuille, Bruno Almeida Lopes, Aurélie Caye-Eude, Marketa Zaliova, Grigory Tsaur, Patrizia Larghero, Vesa Juvonen, Wendy Cuccuini, Rolf Marschalek, Claus Meyer, Gianni Cazzaniga, Audrey Bidet, Mariana Emerenciano, Gabriele Escherich, Bardya Djahanschiri, Hélène Cavé, Zuzana Zermanova, Tobias Feuchtinger, Paul G Ekert, Nicola C. Venn
Publikováno v:
Leukemia
Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico, CNPq: PQ-2017#305529/2017-0 Deutsche Forschungsgemeinschaft, DFG: MA 1876/12-1 Alexander von Humboldt-Stiftung: 88881.136091/2017-01 RVO-VFN64165, 26/203.214/2017 2018.070.1 Associa
Autor:
Rodrigo de Tocantins Calado, Luiz Gonzaga Tone, Rolf Marschalek, Elvis Terci Valera, María Sol Brassesco, Bruno Almeida Lopes, Claus Meyer, Rosane Gomes de Paula Queiroz, Carlos Alberto Scrideli
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
We present a case of an infant who developed pro-B acute lymphoblastic leukemia with a rare and complex MLL-translocation. Cytogenetic analysis of bone marrow cells at diagnosis showed a 46,XY,t(X;11)(p11.2;q23)[13]/46,XY[7] karyotype. Fluorescence i
Autor:
Cíntia Barros Santos-Rebouças, Francianne Gomes Andrade, Gisele Dallapicola Brisson, Rodolpho Mattos Albano, Maria S. Pombo-de-Oliveira, Ingrid Sardou Cezar, Ana Rossini, Orlando Louzada-Neto, Bruno Almeida Lopes
Publikováno v:
Genetics and Molecular Biology, Vol 43, Iss 4 (2020)
Genetics and Molecular Biology
Genetics and Molecular Biology v.43 n.4 2020
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Volume: 43, Issue: 4, Article number: e20200160, Published: 02 DEC 2020
Genetics and Molecular Biology
Genetics and Molecular Biology v.43 n.4 2020
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Volume: 43, Issue: 4, Article number: e20200160, Published: 02 DEC 2020
Early age acute leukemia (EAL) shows a high frequency of KMT2A-rearrangements (KMT2A-r). Previous investigations highlighted double-strand breaks arising from maternal exposure to xenobiotics during pregnancy as a risk factor for EAL and KMT2A-r. In
Autor:
Gerson M. Ferreira, Elaine Sobral da Costa, Isabel M. Carreira, Marcelo Gerardin Poirot Land, Moneeb A.K. Othman, Joana B. Melo, Bruno Almeida Lopes, Maria Luiza Macedo Silva, Thomas Liehr, Mariana Tavares de Souza, Roberto R. Capela de Matos, Mariana Emerenciano, Raul C. Ribeiro
Publikováno v:
Cancer Genetics. 221:25-30
Myeloid neoplasms are a heterogeneous group of hematologic disorders with divergent patterns of cell differentiation and proliferation, as well as divergent clinical courses. Rare recurrent genetic abnormalities related to this group of cancers are a