Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Bruno Alicke"'
Autor:
Rocky Diegmiller, Laurent Salphati, Bruno Alicke, Timothy R. Wilson, Thomas J. Stout, Marc Hafner
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 9, Pp 1183-1193 (2022)
Abstract A major challenge in oncology drug development is to elucidate why drugs that show promising results in cancer cell lines in vitro fail in mouse studies or human trials. One of the fundamental steps toward solving this problem is to better p
Externí odkaz:
https://doaj.org/article/a27b16f4e3af4e099d40f81f20515d08
Autor:
Bruno Alicke, Eugene Varfolomeev, Shi Hui Kaylee Lee, Alexandra Frommlet, Savita Ubhayakar, John G. Quinn, Wayne J. Fairbrother, Robert Jones, Stephen E. Gould, Domagoj Vucic
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/3db51e3eb06e462e8120746067b1af78
Autor:
Bruno Alicke, Jill M Schartner, Amy M Berkley, Sophie M Lehar, Aude-Hélène Capietto, Rafael A Cubas, Stephen E Gould
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The recent success of multiple immunomodulating drugs in oncology highlights the potential of relieving immunosuppression by directly engaging the immune system in the tumor bed to target cancer cells. Durable responses to immune checkpoint inhibitor
Externí odkaz:
https://doaj.org/article/bda05172077840408d6a782c3a92e1bf
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 55K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc838fa47a9d23267b37a858ed4d3f8
https://doi.org/10.1158/1078-0432.22447710
https://doi.org/10.1158/1078-0432.22447710
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 77K, Cell viability following treatment with GNE-317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b14e8b2c62065f86e47c21ee5d4697a
https://doi.org/10.1158/1078-0432.22447713.v1
https://doi.org/10.1158/1078-0432.22447713.v1
Autor:
Stephen E. Gould, Frederic J. de Sauvage, Robert L. Yauch, Tom Januario, Hank La, Patricia Pacheco, Kristina A. West, Bruno Alicke, Harvey Wong
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a94d3e334ec0722a175a9109310ce0
https://doi.org/10.1158/1078-0432.22442118
https://doi.org/10.1158/1078-0432.22442118
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 60K, Plasma Concentrations, Brain Concentrations and Brain-to-Plasma Ratio Measured at the End of Study (42 days) 2 hours Following the Last Daily PO Administration of GNE-317 (40 mg/kg), GDC-0941 (250 mg/kg) or GDC-0980 (10 mg/kg) to GS2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1649707918904ad8cbd83771a80366bc
https://doi.org/10.1158/1078-0432.22447701
https://doi.org/10.1158/1078-0432.22447701
Autor:
Stephen E. Gould, Cornelis E.C.A. Hop, Lori S. Friedman, Jay Tibbitts, Frank-Peter Theil, Erin McNamara, Hank La, Xiao Ding, Bruno Alicke, Edna F. Choo, Harvey Wong
PDF file, 91KB, Population Pharmacodynamic Parameter Estimates for Anti-Cancer Agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f81c2c04343c4e4155724e9ae9a38ba
https://doi.org/10.1158/1078-0432.22446335
https://doi.org/10.1158/1078-0432.22446335
Autor:
Stephen E. Gould, Cornelis E.C.A. Hop, Lori S. Friedman, Jay Tibbitts, Frank-Peter Theil, Erin McNamara, Hank La, Xiao Ding, Bruno Alicke, Edna F. Choo, Harvey Wong
PDF file, 50KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae861e22cb0aa62edbeccead03f489f
https://doi.org/10.1158/1078-0432.22446344.v1
https://doi.org/10.1158/1078-0432.22446344.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 116K, Plot of CNS-MPO score vs. efflux ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec1963a4dc8dbcd09c67292559efb78
https://doi.org/10.1158/1078-0432.22447716.v1
https://doi.org/10.1158/1078-0432.22447716.v1