Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bruno, Tigani"'
Autor:
Lorenz Meinel, Janet Dawson, Tessa Lühmann, Amanda Littlewood-Evans, Bruno Tigani, Martina Raschig, Valerie Spieler, Marie-Gabrielle Ludwig, Hilmar Ebersbach, Caterina Safina, Björn ter Mors, Thomas Müller, Klaus Seuwen
Publikováno v:
Journal of Controlled Release. 326:172-180
Anti-inflammatory cytokines are a promising class of therapeutics for treatment of rheumatoid arthritis (RA), but their use is currently limited by a rapid clearance and systemic toxicity. Interleukin-4 is a small cytokine with potential for RA thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ba66f3cba718f4e4dbe3cdc5422ff5
https://doi.org/10.1016/j.jconrel.2020.07.005
https://doi.org/10.1016/j.jconrel.2020.07.005
Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands
Autor:
Jeffrey T. Bagdanoff, Thomas M. Smith, Martin Allan, Peter O’Donnell, Zachary Nguyen, Elizabeth A. Moore, Jason Baird, Shuangxi Wang, Vanitha Subramanian, Bruno Tigani, David O. Nettleton, Lauren G. Monovich, Ian Lewis, Alec N. Flyer, Brian Granda, John W. Blankenship, David Barnes-Seeman, Kevin B. Clairmont
Publikováno v:
Cell Chemical Biology. 30:97-109.e9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda907f4423e41fe5feee324e9c215d0
https://doi.org/10.1016/j.chembiol.2022.12.003
https://doi.org/10.1016/j.chembiol.2022.12.003
Autor:
Christine Egger, Catherine Cannet, Christelle Gérard, Elizabeth Jarman, Gabor Jarai, Agnès Feige, Thomas Suply, Arthur Micard, Andrew Dunbar, Bruno Tigani, Nicolau Beckmann
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63432 (2013)
Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal aspiration of bleomycin as an a
Externí odkaz:
https://doaj.org/article/197b43e4cb5a4fe384ba6f92725a2730
Autor:
Stephanie Valeaux, Juan Zhang, Rainer Kneuer, Janet Dawson, Saijel Patel, Tina Rubic-Schneider, Tobias Junt, Perrine Loesle, Sophie Sarret, Nina Gommermann, Bruno Tigani, José M. Carballido, Verena Apfel, Amanda Littlewood-Evans, Alban Muller
Publikováno v:
The Journal of Experimental Medicine
Littlewood-Evans et al. demonstrate that extracellular succinate leads to the propagation of inflammatory macrophage activation, providing translational evidence to support the development of GPR91 antagonists for the treatment of rheumatoid arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e29df82da3188d4f888540015f1c86
https://doi.org/10.1084/jem.20160061
https://doi.org/10.1084/jem.20160061
Autor:
Sabine Guth-Gundel, Benjamin R. Freedman, Michael Schuleit, Andreas Kuttler, Bruno Tigani, Mara Fornaro, Michaela Kneissel, Alexander G. Stafford, Jianyu Li, Anne Basler, David J. Mooney, Arno Doelemeyer, Nathalie Accart, Kuno Wuersch, Eckhard Weber, Christine Halleux
Publikováno v:
Advanced healthcare materials. 7(9)
Hydrogels are under active development for controlled drug delivery, but their clinical translation has been limited by low drug loading capacity, deficiencies in mechanical toughness and storage stability, and poor control over the drug release that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4782104f76d7d2d64d9bc9108806419
https://pubmed.ncbi.nlm.nih.gov/29441702
https://pubmed.ncbi.nlm.nih.gov/29441702
Autor:
Christelle Gérard, Christine Egger, Bruno Tigani, Andrew Dunbar, Catherine Cannet, Nicolau Beckmann
Publikováno v:
Journal of Magnetic Resonance Imaging. 41:755-764
Purpose To assess whether hyaluronic acid, a building block of proteoglycans and extracellular matrix with hydrophilic characteristics, might contribute to magnetic resonance imaging (MRI)-detected proton signals elicited by bleomycin in the lung. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25551d4dda9c18de0e3a062dc402c1e0
https://doi.org/10.1002/jmri.24612
https://doi.org/10.1002/jmri.24612
Autor:
Bruno Tigani, Andrew Dunbar, Corinne Debon, Nadine Stohler, Christine Egger, Catherine Cannet, Jianping Li, Christelle Gérard, Nicolau Beckmann
Publikováno v:
Journal of Magnetic Resonance Imaging. 41:829-840
Purpose To assess with magnetic resonance imaging (MRI) adriamycin-induced nephropathy in living rats, an established model for proteinuric renal disease was used. Materials and Methods Functional information of contrast agent clearance was obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b369f27ef63122ab2f0f11816e1c4fb1
https://doi.org/10.1002/jmri.24603
https://doi.org/10.1002/jmri.24603
Autor:
Harry Karmouty-Quintana, Yannick Crémillieux, Catherine Cannet, François-Xavier Blé, Nicolau Beckmann, Bruno Tigani, Stefan Zurbruegg, Alexandre Trifilieff
Publikováno v:
European Journal of Radiology. 64:381-396
Current techniques to evaluate the efficacy of potential treatments for airways diseases in preclinical models are generally invasive and terminal. In the past few years, the flexibility of magnetic resonance imaging (MRI) to obtain anatomical and fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a27a4eeac005a7929f79d7552e429b
https://doi.org/10.1016/j.ejrad.2007.08.012
https://doi.org/10.1016/j.ejrad.2007.08.012
Autor:
Elisabeth Schaeublin, Harry Karmouty-Quintana, John R. Fozard, Stefan Zurbruegg, Catherine Cannet, Bruno Tigani, François-Xavier Blé, Nicolau Beckmann
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 292:L644-L653
Magnetic resonance imaging (MRI) has been used previously to follow noninvasively inflammatory processes in rat acute models of lung inflammation. Here the technique was applied to a model involving repeated intratracheal administration of ovalbumin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938589dd5eebc7c30d51f2f2bf47030f
https://doi.org/10.1152/ajplung.00122.2006
https://doi.org/10.1152/ajplung.00122.2006
Publikováno v:
PROTEOMICS. 4:2101-2110
The protein content of bronchoalveolar lavage fluid (BALF) from actively sensitised Brown Norway (BN) rats challenged with allergen (ovalbumin, OA) and from naïve Brown Norway rats challenged with endotoxin (lipopolysaccharide, LPS) was analyzed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44d9cdff4e6e3aa124173411701067f
https://doi.org/10.1002/pmic.200300727
https://doi.org/10.1002/pmic.200300727