Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Bruno, Manadas"'
Autor:
Daniela Moutinho, Vera M. Mendes, Alessandro Caula, Sara C. Madeira, Inês Baldeiras, Manuela Guerreiro, Sandra Cardoso, Johan Gobom, Henrik Zetterberg, Isabel Santana, Alexandre De Mendonça, Helena Aidos, Bruno Manadas
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-6 (2024)
Externí odkaz:
https://doaj.org/article/6de94bf9ced94bc1ba86e286073d7304
Autor:
Joana M. S. Cardoso, Bruno Manadas, Isabel Abrantes, Lee Robertson, Susana C. Arcos, Maria Teresa Troya, Alfonso Navas, Luís Fonseca
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Pine wilt disease (PWD) is a devastating forest disease caused by the pinewood nematode (PWN), Bursaphelenchus xylophilus, a migratory endoparasite that infects several coniferous species. During the last 20 years, advances have been made fo
Externí odkaz:
https://doaj.org/article/8c2b0f28864b4b92b3154f9502cacdc5
Autor:
Cátia Santa, Diana Rodrigues, Joana F. Coelho, Sandra I. Anjo, Vera M. Mendes, Diogo Bessa-Neto, Michael J. Dunn, David Cotter, Graça Baltazar, Patrícia Monteiro, Bruno Manadas
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Striatal dysfunction has been implicated in the pathophysiology of schizophrenia, a disorder characterized by positive symptoms such as hallucinations and delusions. Haloperidol is a typical antipsychotic medication used in the treatment of
Externí odkaz:
https://doaj.org/article/7414de2ea7014d4ebee8488a19a3acaf
Autor:
José Lentilhas-Graça, Diogo J. Santos, João Afonso, Andreia Monteiro, Andreia G. Pinho, Vera M. Mendes, Marta S. Dias, Eduardo D. Gomes, Rui Lima, Luís S. Fernandes, Fernando Fernandes-Amorim, Inês M. Pereira, Nídia de Sousa, Jorge R. Cibrão, Aline M. Fernandes, Sofia C. Serra, Luís A. Rocha, Jonas Campos, Tiffany S. Pinho, Susana Monteiro, Bruno Manadas, António J. Salgado, Ramiro D. Almeida, Nuno A. Silva
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe inflammatory response after spinal cord injury (SCI) is an important contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of activation states, however, the microenvironment at the SCI site favors macrophag
Externí odkaz:
https://doaj.org/article/3e080e26efa74ac2aba7ce204297b740
A Comparative Analysis of the Venom System between Two Morphotypes of the Sea Anemone Actinia equina
Autor:
Maria Alcaide, Inês Moutinho Cabral, Lara Carvalho, Vera M. Mendes, António P. Alves de Matos, Bruno Manadas, Leonor Saúde, Mariaelena D’Ambrosio, Pedro M. Costa
Publikováno v:
Animals, Vol 14, Iss 6, p 981 (2024)
The current study investigates the venom-delivery system of green and red morphotypes of the sea anemone Actinia equina to disclose its potential as a source of bioactive compounds. We compared the two morphotypes using electron and optical microscop
Externí odkaz:
https://doaj.org/article/5203233874554a908ef589bf810c10ee
Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides
Autor:
Ana Maranha, Mafalda Costa, Jorge Ripoll-Rozada, José A. Manso, Vanessa Miranda, Vera M. Mendes, Bruno Manadas, Sandra Macedo-Ribeiro, M. Rita Ventura, Pedro José Barbosa Pereira, Nuno Empadinhas
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
The mechanism of methylmannose polysaccharide (MMP) biogenesis in nontuberculous mycobacteria (NTM) is characterized, which involves an MMP-specific hydrolase (MmpH) and a rare mannosyltransferase (ManT). MmpH and ManT structures are presented.
Externí odkaz:
https://doaj.org/article/160414c28e904d199761ec1e0d62082e
Autor:
Diana Rodrigues, Luis Jacinto, Margarida Falcão, Ana Carolina Castro, Alexandra Cruz, Cátia Santa, Bruno Manadas, Fernanda Marques, Nuno Sousa, Patricia Monteiro
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Chronic stress can trigger or worsen motor symptoms in neuropsychiatric disorders. Here, the authors show that SOM interneurons in the striatum are involved in stress-induced motor behaviors.
Externí odkaz:
https://doaj.org/article/5967e588f14c42969dbcc7715adbd293
Autor:
Margarida Coelho, João Capela, Vera M. Mendes, João Pacheco, Margarida Sá Fernandes, Isabel Amendoeira, John G. Jones, Luís Raposo, Bruno Manadas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 376 (2023)
Thyroid cancer is a common malignancy of the endocrine system. Nodules are routinely evaluated for malignancy risk by fine needle aspiration biopsy (FNAB), and in cases such as follicular lesions, differential diagnosis between benign and malignant n
Externí odkaz:
https://doaj.org/article/d617590ba86b4e7499eebf50092fe0a5
Autor:
Sónia Campos, Ana P. Rodrigo, Inês Moutinho Cabral, Vera M. Mendes, Bruno Manadas, Mariaelena D’Ambrosio, Pedro M. Costa
Publikováno v:
Toxins, Vol 15, Iss 11, p 655 (2023)
The immense biodiversity of marine invertebrates makes them high-value targets for the prospecting of novel bioactives. The present study investigated proteinaceous toxins secreted by the skin and proboscis of Glycera alba (Annelida: Polychaeta), who
Externí odkaz:
https://doaj.org/article/b52c5fc39e4b44b6a88b823157481f5d
Autor:
Rita I. Pacheco, Maria I. Cristo, Sandra I. Anjo, Andreia F. Silva, Maria Inês Sousa, Renata S. Tavares, Ana Paula Sousa, Teresa Almeida Santos, Mariana Moura-Ramos, Francisco Caramelo, Bruno Manadas, João Ramalho-Santos, Sandra Gomes Amaral
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1462 (2023)
The global trend of rising (male) infertility is concerning, and the unidentifiable causes in half of the cases, the so-called unknown origin male infertility (UOMI), demands a better understanding and assessment of both external/internal factors and
Externí odkaz:
https://doaj.org/article/f16c208205e149bc84850f103ae30f29