Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bruno, Madio"'
Autor:
Lauren M. Ashwood, Khaled A. Elnahriry, Zachary K. Stewart, Thomas Shafee, Muhammad Umair Naseem, Tibor G. Szanto, Chloé A. van der Burg, Hayden L. Smith, Joachim M. Surm, Eivind A. B. Undheim, Bruno Madio, Brett R. Hamilton, Shaodong Guo, Dorothy C. C. Wai, Victoria L. Coyne, Matthew J. Phillips, Kevin J. Dudley, David A. Hurwood, Gyorgy Panyi, Glenn F. King, Ana Pavasovic, Raymond S. Norton, Peter J. Prentis
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-25 (2023)
Abstract Background The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in Actiniarians remain uncharacterised. One such peptide family, sea ane
Externí odkaz:
https://doaj.org/article/21a4debffec04564ae9a29b4a8776746
Autor:
Lauren M. Ashwood, Michela L. Mitchell, Bruno Madio, David A. Hurwood, Glenn F. King, Eivind A. B. Undheim, Raymond S. Norton, Peter J. Prentis
Publikováno v:
Toxins, Vol 13, Iss 7, p 452 (2021)
Phylum Cnidaria is an ancient venomous group defined by the presence of cnidae, specialised organelles that serve as venom delivery systems. The distribution of cnidae across the body plan is linked to regionalisation of venom production, with tissue
Externí odkaz:
https://doaj.org/article/0ab99c3f64d74c28ba03a28da7b39f7f
Autor:
Brett Hamilton, David A. Hurwood, Marymegan Daly, Bruno Madio, Peter J. Prentis, Eivind A. B. Undheim, Lauren M. Ashwood, Glenn F. King
Publikováno v:
Molecular Ecology. 31:866-883
The phylum Cnidaria is the oldest extant venomous group and is defined by the presence of nematocysts, specialized organelles responsible for venom production and delivery. Although toxin peptides and the cells housing nematocysts are distributed acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84feadbac0d507a5ace429c8a1a2d141
https://doi.org/10.1111/mec.16286
https://doi.org/10.1111/mec.16286
Autor:
Mahdokht Jouiaei, Angel A. Yanagihara, Bruno Madio, Timo J. Nevalainen, Paul F. Alewood, Bryan G. Fry
Publikováno v:
Toxins, Vol 7, Iss 6, Pp 2251-2271 (2015)
Cnidarians are the oldest extant lineage of venomous animals. Despite their simple anatomy, they are capable of subduing or repelling prey and predator species that are far more complex and recently evolved. Utilizing specialized penetrating nematocy
Externí odkaz:
https://doaj.org/article/f4439a8ef5194d84adcc171e9ddb47fe
Autor:
Lauren M. Ashwood, Khaled A. Elnahriry, Zachary K. Stewart, Thomas Shafee, Muhammad Umair Naseem, Tibor G. Szanto, Chloé A. van der Burg, Hayden L. Smith, Joachim M. Surm, Eivind A.B. Undheim, Bruno Madio, Brett R. Hamilton, Shaodong Guo, Dorothy C.C. Wai, Victoria L. Coyne, Matthew J. Phillips, Kevin J. Dudley, David A. Hurwood, Gyorgy Panyi, Glenn F. King, Ana Pavasovic, Raymond S. Norton, Peter J. Prentis
ShK fromStichodactyla helianthushas established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in actinarians remain uncharacterised. One such peptide family, sea anemone 8 (SA8), is present in all f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65099c4077a6d6a842da8bc1eb44862b
https://doi.org/10.1101/2022.12.08.518931
https://doi.org/10.1101/2022.12.08.518931
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 325 (2019)
Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different molecular scaffolds reported to date. These venom components have traditionally been classified according to pharmacological activity and amino acid sequence.
Externí odkaz:
https://doaj.org/article/27e4a0f71dbd427bbc84fb1aa9f17eab
Autor:
André J. Zaharenko, Jan Tytgat, José C. Freitas, Adriano M. C. Pimenta, José E. P. W. Bicudo, Gabriela G. Montandon, Juliana S. Cassoli, Bruno Madio, Diego J. B. Orts, Steve Peigneur
Publikováno v:
Marine Drugs, Vol 11, Iss 3, Pp 655-679 (2013)
Sea anemone (Cnidaria, Anthozoa) venom is an important source of bioactive compounds used as tools to study the pharmacology and structure-function of voltage-gated K+ channels (KV). These neurotoxins can be divided into four different types, accordi
Externí odkaz:
https://doaj.org/article/9417cb03d6ef4a22879767f2a0d6f8d0
Autor:
Brett Hamilton, Hayden L Smith, Joachim M. Surm, Glenn F. King, Eivind A. B. Undheim, Ana Pavasovic, Peter J. Prentis, Bruno Madio, Chloé A. van der Burg
Publikováno v:
Molecular Ecology. 28:2272-2289
Members of phylum Cnidaria are an ancient group of venomous animals and rely on a number of specialized tissues to produce toxins in order to fulfil a range of ecological roles including prey capture, defence against predators, digestion and aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a323d211ff175a2b45a780804d50cb9b
https://doi.org/10.1111/mec.15084
https://doi.org/10.1111/mec.15084
Autor:
Brett Hamilton, Paul F. Alewood, Yanni K.-Y. Chin, Jennifer J. Smith, Ben Cristofori-Armstrong, Eivind A. B. Undheim, Jan Tytgat, Zoltan Dekan, Sónia Troeira Henriques, Bruno Madio, Steve Peigneur, Glenn F. King, Berin A. Boughton
Publikováno v:
Cellular and Molecular Life Sciences
Sea anemone venoms have long been recognized as a rich source of peptides with interesting pharmacological and structural properties, but they still contain many uncharacterized bioactive compounds. Here we report the discovery, three-dimensional str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfcdb65e809054c6233015877da770f
https://doi.org/10.1007/s00018-018-2897-6
https://doi.org/10.1007/s00018-018-2897-6
Publikováno v:
Journal of Proteomics. 166:83-92
More than a century of research on sea anemone venoms has shown that they contain a diversity of biologically active proteins and peptides. However, recent omics studies have revealed that much of the venom proteome remains unexplored. We used, for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf3c0dd09621b693cf3790ff39bbace
https://doi.org/10.1016/j.jprot.2017.07.007
https://doi.org/10.1016/j.jprot.2017.07.007