Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Bruno, Coutard"'
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1354 (2023)
Viruses are known to infect most types of organisms. In humans, they can cause several diseases that range from mild to severe. Although many antiviral therapies have been developed, viral infections continue to be a leading cause of morbidity and mo
Externí odkaz:
https://doaj.org/article/3ebb9d8aaf0a4508994f8e5d42086bac
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Jingmenviruses are a group of viruses identified recently, in 2014, and currently classified by the International Committee on Taxonomy of Viruses as unclassified Flaviviridae. These viruses closely related to flaviviruses are unique due to the segme
Externí odkaz:
https://doaj.org/article/8141d159c01a4eb08745699c40aa7307
Autor:
Jean-Sélim Driouich, Maxime Cochin, Guillaume Lingas, Grégory Moureau, Franck Touret, Paul-Rémi Petit, Géraldine Piorkowski, Karine Barthélémy, Caroline Laprie, Bruno Coutard, Jérémie Guedj, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Favipiravir has broad-spectrum antiviral activity against a variety of RNA viruses. Here the authors investigate the safety, pharmacokinetics and anti-SARS-CoV-2 efficacy of different drug dosage in the a Syrian hamster model of infection and, combin
Externí odkaz:
https://doaj.org/article/28b65fe72e8643d09a5316e736cd7471
Autor:
Scarlett Sett, PhD, Carolina dos Santos Ribeiro, MSc, Christine Prat, PhD, George Haringhuizen, LLM, Amber Hartman Scholz, PhD, Tatjana Avšič, Carrie Batten, Maria Serena Beato, Hervé Bourhy, Antonino Di Caro, Rémi Charrel, Bruno Coutard, Jan Felix Drexler, Christian Drosten, Anthony R. Fooks, Boris Klempa, Marion Koopmans, Thomas Klimkait, Stephan Günther, Jean-Claude Manuguerra, Ali Mirazimi, Thomas C. Mettenleiter, Florence Komurian-Pradel, Sven Reiche, Chantal Reusken, Jean-Louis Romette, Sylvie van der Werf, David Williams
Publikováno v:
The Lancet Microbe, Vol 3, Iss 4, Pp e316-e323 (2022)
Summary: Biobanking infrastructures, which are crucial for responding early to new viral outbreaks, share pathogen genetic resources in an affordable, safe, and impartial manner and can provide expertise to address access and benefit-sharing issues.
Externí odkaz:
https://doaj.org/article/e2796a3c1fb64820b0fbf52d82eb94c1
Autor:
Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le, Johanna Huchting, Franck Touret, Géraldine Piorkowski, Véronique Fattorini, François Ferron, Etienne Decroly, Chris Meier, Bruno Coutard, Olve Peersen, Bruno Canard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Favipiravir (T-705) is an inhibitor of viral RNA-dependent-RNA-polymerases (RdRp) and clinical trials for the treatment of COVID-19 are ongoing. Here, the authors show that SARS-CoV nsp12 is the fastest known viral RdRp and they provide insights into
Externí odkaz:
https://doaj.org/article/6f077279cc5545ac8b6524fe1944a7d7
Autor:
Eva Lopez, Margot Barthélémy, Cécile Baronti, Shirley Masse, Alessandra Falchi, Fabien Durbesson, Renaud Vincentelli, Xavier de Lamballerie, Rémi Charrel, Bruno Coutard
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103329- (2021)
Summary: Since the beginning of the COVID-19 pandemics, variants have emerged. Some of them display increased transmissibility and/or resistance to immune response. Most of the mutations involved in the functional adaptation are found in the receptor
Externí odkaz:
https://doaj.org/article/40e3d47cc36e438991142d8e8cfecf7a
Autor:
Ramona Mögling, Adam Meijer, Natasa Berginc, Sylvia Bruisten, Remi Charrel, Bruno Coutard, Isabella Eckerle, Vincent Enouf, Olav Hungnes, Gülay Korukluoglu, Thanos Kossyvakis, Andreas Mentis, Richard Molenkamp, Shaman Muradrasoli, Anna Papa, Fiona Pigny, Laurence Thirion, Sylvie van der Werf, Chantal Reusken
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 8, Pp 1944-1946 (2020)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 th
Externí odkaz:
https://doaj.org/article/007d820b571c407b9dcb109f077665c5
Autor:
Carole Yaacoub, Rim Wehbe, Yahya Salma, Dany El-Obeid, Romeo El Bersaoui, Bruno Coutard, Ziad Fajloun
Publikováno v:
Molecules, Vol 27, Iss 5, p 1653 (2022)
Bee venom (BV) is one of the most remarkable natural products that has been a subject of studies since ancient times. Recent studies have shown that Apis mellifera syriaca venom possesses antibacterial as well as cytotoxic effects on cancer cell line
Externí odkaz:
https://doaj.org/article/dc113c8761ac42dba1224ffe88c74ce8
Autor:
Maria D. Politi, Angelo Gallo, Georgios Bouras, Maria Birkou, Bruno Canard, Bruno Coutard, Georgios A. Spyroulias
Publikováno v:
Biomolecular NMR Assignments
Biomolecular NMR Assignments, 2022, ⟨10.1007/s12104-022-10111-5⟩
Biomolecular NMR Assignments, 2022, ⟨10.1007/s12104-022-10111-5⟩
The genome of Hepatitis E virus (HEV) is 7.2 kilobases long and has three open reading frames. The largest one is ORF1, encoding a non-structural protein involved in the replication process, and whose processing is ill-defined. The ORF1 protein is a
Autor:
Jessica Denis, Sarah Attoumani, Patrick Gravier, Bernard Tenebray, Annabelle Garnier, Sébastien Briolant, Franck de Laval, Véronique Chastres, Gilda Grard, Isabelle Leparc-Goffart, Bruno Coutard, Cyril Badaut
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 9, p e0007747 (2019)
BackgroundZika virus (ZIKV) and Dengue virus (DENV) are often co-endemic. The high protein-sequence homology of flaviviruses renders IgG induced by and directed against them highly cross-reactive against their antigen(s), as observed on a large set o
Externí odkaz:
https://doaj.org/article/af83c23ff29548d8aafac43ab821cf0a