Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Bruno, Antonny"'
Autor:
Eugenio de la Mora, Manuela Dezi, Aurélie Di Cicco, Joëlle Bigay, Romain Gautier, John Manzi, Joël Polidori, Daniel Castaño-Díez, Bruno Mesmin, Bruno Antonny, Daniel Lévy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Here authors designed an in vitro MCS suitable for cryotomography and sub-tomogram analysis which sheds li
Externí odkaz:
https://doaj.org/article/2aa2a1f7d9a14196818f11d331413f00
Autor:
Manuel Giménez-Andrés, Tadej Emeršič, Sandra Antoine-Bally, Juan Martin D'Ambrosio, Bruno Antonny, Jure Derganc, Alenka Čopič
Publikováno v:
eLife, Vol 10 (2021)
Numerous proteins target lipid droplets (LDs) through amphipathic helices (AHs). It is generally assumed that AHs insert bulky hydrophobic residues in packing defects at the LD surface. However, this model does not explain the targeting of perilipins
Externí odkaz:
https://doaj.org/article/feb96be726824530b92c9c9c35541f93
Autor:
Alenka Čopič, Sandra Antoine-Bally, Manuel Giménez-Andrés, César La Torre Garay, Bruno Antonny, Marco M. Manni, Sophie Pagnotta, Jeanne Guihot, Catherine L. Jackson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid dr
Externí odkaz:
https://doaj.org/article/492f328f8d8144b1b134824fe07962c6
Autor:
Marco M Manni, Marion L Tiberti, Sophie Pagnotta, Hélène Barelli, Romain Gautier, Bruno Antonny
Publikováno v:
eLife, Vol 7 (2018)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our un
Externí odkaz:
https://doaj.org/article/e613b9af60064d0b9cb5e79e77a18c06
Publikováno v:
Current Opinion in Cell Biology. 82:102172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe643c8f52a4d47b4c39b3d5870ccb9
https://doi.org/10.1016/j.ceb.2023.102172
https://doi.org/10.1016/j.ceb.2023.102172
Autor:
Mélody Subra, Manuela Dezi, Joëlle Bigay, Sandra Lacas-Gervais, Aurélie Di Cicco, Ana Rita Dias Araújo, Sophie Abélanet, Lucile Fleuriot, Delphine Debayle, Romain Gautier, Amanda Patel, Fanny Roussi, Bruno Antonny, Daniel Lévy, Bruno Mesmin
SUMMARYMembrane contact sites (MCSs) between organelles are heterogeneous in shape, composition and dynamics. Despite this diversity, VAP proteins act as receptors for multiple FFAT motif-containing proteins and drive the formation of most MCSs invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facd2dee7c78fe704a51eaf4dc97b7f9
https://doi.org/10.1101/2022.05.13.491839
https://doi.org/10.1101/2022.05.13.491839
Publikováno v:
eLife, Vol 5 (2016)
When small phosphatidylcholine liposomes are added to perforated cells, they bind preferentially to the Golgi suggesting an exceptional avidity of this organelle for curved membranes without stereospecific interactions. We show that the cis golgin GM
Externí odkaz:
https://doaj.org/article/25d0ecff4dd64d5b948bd1e97aadd927
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2020, 36 (2), pp.130-136. ⟨10.1051/medsci/2020009⟩
médecine/sciences, EDP Sciences, 2020, 36 (2), pp.130-136. ⟨10.1051/medsci/2020009⟩
International audience; Cholesterol is synthesized in the endoplasmic reticulum (RE) and then transported to cellular compartments whose functions require high cholesterol levels. Here, we describe the mechanism by which cholesterol is transported fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cdc1b5e7a9013befdd7cca981c91b3
https://doi.org/10.1051/medsci/2020009
https://doi.org/10.1051/medsci/2020009
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 45 (2018)
Amphipathic helices (AHs), a secondary feature found in many proteins, are defined by their structure and by the segregation of hydrophobic and polar residues between two faces of the helix. This segregation allows AHs to adsorb at polar–apolar int
Externí odkaz:
https://doaj.org/article/52784150ae0b48738d4cc6fcca07d547
Autor:
Dávid Kovács, Anne-Sophie Gay, Lucile Fleuriot, Delphine Debayle, Ana Rita Dias Araújo, Amanda Patel, Bruno Mesmin, Frédéric Luton, Bruno Antonny
Golgi lipid environment regulates sorting and cargo secretion. However, the mechanisms that spatiotemporally control the lipid composition of the secretory membranes to drive cargo trafficking are poorly understood. Lipid transfer proteins regulate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94df76d3c9b64a986ddae358f4695794
https://doi.org/10.1101/2021.12.09.471984
https://doi.org/10.1101/2021.12.09.471984