Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brunner SF"'
Autor:
Ellis P; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata Limited, The Glenn Berge Building, Babraham Research Campus, Babraham, UK., Moore L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Butler TM; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Brunner SF; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Lee-Six H; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Osborne R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata Limited, The Glenn Berge Building, Babraham Research Campus, Babraham, UK., Farr B; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Lawson ARJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Cagan A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Stratton MR; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Martincorena I; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Campbell PJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature protocols [Nat Protoc] 2023 Jun; Vol. 18 (6), pp. 1979.
Autor:
Ng SWK; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Rouhani FJ; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK.; Department of Surgery, Addenbrooke's Hospital, Cambridge, UK., Brunner SF; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Brzozowska N; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Aitken SJ; CRUK Cambridge Institute, Cambridge, UK.; Department of Pathology, Addenbrooke's Hospital, Cambridge, UK.; MRC Toxicology Unit, University of Cambridge, Cambridge, UK., Yang M; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Abascal F; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Moore L; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Nikitopoulou E; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Chappell L; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Leongamornlert D; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Ivovic A; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Robinson P; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Butler T; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Williams N; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Teague J; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Raine K; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Butler AP; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Hooks Y; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Wilson B; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Birtchnell N; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Naylor H; Department of Surgery, Addenbrooke's Hospital, Cambridge, UK., Davies SE; Department of Pathology, Addenbrooke's Hospital, Cambridge, UK., Stratton MR; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Martincorena I; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK., Frezza C; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Hoare M; CRUK Cambridge Institute, Cambridge, UK. Matthew.Hoare@cruk.cam.ac.uk.; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Matthew.Hoare@cruk.cam.ac.uk., Campbell PJ; Cancer Genome Project, Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Stem Cell Institute, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Oct; Vol. 598 (7881), pp. 473-478. Date of Electronic Publication: 2021 Oct 13.
Autor:
Shoshani O; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Brunner SF; Wellcome Sanger Institute, Hinxton, UK., Yaeger R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ly P; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Nechemia-Arbely Y; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Kim DH; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Fang R; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Castillon GA; National Center for Microscopy and Imaging Research (NCMIR), University of California at San Diego, La Jolla, CA, USA., Yu M; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Li JSZ; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Sun Y; Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA., Ellisman MH; National Center for Microscopy and Imaging Research (NCMIR), University of California at San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California at San Diego, La Jolla, CA, USA., Ren B; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk., Cleveland DW; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA. dcleveland@health.ucsd.edu.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA. dcleveland@health.ucsd.edu.
Publikováno v:
Nature [Nature] 2021 Mar; Vol. 591 (7850), pp. E19.
Autor:
Shoshani O; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Brunner SF; Wellcome Sanger Institute, Hinxton, UK., Yaeger R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ly P; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Nechemia-Arbely Y; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Kim DH; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Fang R; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Castillon GA; National Center for Microscopy and Imaging Research (NCMIR), University of California at San Diego, La Jolla, CA, USA., Yu M; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Li JSZ; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Sun Y; Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA., Ellisman MH; National Center for Microscopy and Imaging Research (NCMIR), University of California at San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California at San Diego, La Jolla, CA, USA., Ren B; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk., Cleveland DW; Ludwig Cancer Research, University of California at San Diego, La Jolla, CA, USA. dcleveland@health.ucsd.edu.; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA. dcleveland@health.ucsd.edu.
Publikováno v:
Nature [Nature] 2021 Mar; Vol. 591 (7848), pp. 137-141. Date of Electronic Publication: 2020 Dec 23.
Autor:
Ellis P; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata Limited, The Glenn Berge Building, Babraham Research Campus, Babraham, UK., Moore L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Butler TM; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Brunner SF; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Lee-Six H; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Osborne R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata Limited, The Glenn Berge Building, Babraham Research Campus, Babraham, UK., Farr B; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Lawson ARJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Cagan A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Stratton MR; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Martincorena I; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Campbell PJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature protocols [Nat Protoc] 2021 Feb; Vol. 16 (2), pp. 841-871. Date of Electronic Publication: 2020 Dec 14.
Autor:
Moore L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Leongamornlert D; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Coorens THH; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Sanders MA; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Ellis P; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK.; Inivata Ltd, Cambridge, UK., Dentro SC; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Dawson KJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Butler T; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Rahbari R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Mitchell TJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Maura F; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK.; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nangalia J; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Tarpey PS; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Brunner SF; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Lee-Six H; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Hooks Y; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Moody S; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Mahbubani KT; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge NIHR Biomedical Research Centre, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Jimenez-Linan M; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Brosens JJ; Tommy's National Miscarriage Research Centre, Warwick Medical School, University of Warwick, Coventry, UK., Iacobuzio-Donahue CA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Martincorena I; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge NIHR Biomedical Research Centre, Cambridge, UK., Campbell PJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK., Stratton MR; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Cambridge, UK. mrs@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2020 Apr; Vol. 580 (7805), pp. 640-646. Date of Electronic Publication: 2020 Apr 22.
Autor:
Brunner SF; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Roberts ND; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Wylie LA; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Moore L; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Aitken SJ; CRUK Cambridge Institute, Cambridge, UK.; Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Davies SE; Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Sanders MA; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Ellis P; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Alder C; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Hooks Y; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Abascal F; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Stratton MR; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Martincorena I; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Hoare M; CRUK Cambridge Institute, Cambridge, UK. Matthew.Hoare@cruk.cam.ac.uk.; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Matthew.Hoare@cruk.cam.ac.uk., Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Department of Haematology and Stem Cell Institute, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2019 Oct; Vol. 574 (7779), pp. 538-542. Date of Electronic Publication: 2019 Oct 23.
Autor:
Ly P; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA. peter.ly@utsouthwestern.edu.; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA. peter.ly@utsouthwestern.edu., Brunner SF; Wellcome Sanger Institute, Hinxton, UK., Shoshani O; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA., Kim DH; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA., Lan W; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA., Pyntikova T; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Flanagan AM; University College London Cancer Institute, London, UK.; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, UK., Behjati S; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK., Page DC; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Cleveland DW; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA. dcleveland@ucsd.edu.
Publikováno v:
Nature genetics [Nat Genet] 2019 Apr; Vol. 51 (4), pp. 705-715. Date of Electronic Publication: 2019 Mar 04.
Autor:
Zhang MS; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Brunner SF; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Huguenin-Dezot N; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Liang AD; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Schmied WH; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Rogerson DT; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK., Chin JW; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, England, UK.
Publikováno v:
Nature methods [Nat Methods] 2017 Jul; Vol. 14 (7), pp. 729-736. Date of Electronic Publication: 2017 May 29.
Autor:
Kochanowski K; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Life Science Zurich PhD Program on Systems Biology, Zurich, Switzerland., Gerosa L; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Life Science Zurich PhD Program on Systems Biology, Zurich, Switzerland., Brunner SF; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland., Christodoulou D; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Life Science Zurich PhD Program on Systems Biology, Zurich, Switzerland., Nikolaev YV; Institute of Molecular Biology & Biophysics, ETH Zurich, Zurich, Switzerland., Sauer U; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland sauer@imsb.biol.ethz.ch.
Publikováno v:
Molecular systems biology [Mol Syst Biol] 2017 Jan 03; Vol. 13 (1), pp. 903. Date of Electronic Publication: 2017 Jan 03.