Výsledky vyhledávání - "Brunn, G. J."

Monocyte-mediated T cell suppression by HIV-2 envelope proteins

Autor: Cavaleiro, R., Brunn, G. J., Albuquerque, A. S., Victorino, R. M., Platt, J. L., Sousa, A. E.

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
HIV-2 is associated with an attenuated form of HIV disease. We investigate here the immunosuppressive effects of the HIV-2 envelope protein, gp105. We found that gp105 suppresses activation of T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b06daffef1c4a0b2e6c2d30fc1394610
https://hdl.handle.net/10451/18304

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002

Autor: Brunn, G J, Williams, J, Sabers, C, Wiederrecht, G, Lawrence, J C, Abraham, R T

The immunosuppressant, rapamycin, inhibits cell growth by interfering with the function of a novel kinase, termed mammalian target of rapamycin (mTOR). The putative catalytic domain of mTOR is similar to those of mammalian and yeast phosphatidylinosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c28bd74a81af5e3636141b25b66fca1
https://europepmc.org/articles/PMC452270/

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.

Autor: Brunn, G. J., Williams, J., Sabers, C., Wiederrecht, G., Lawrence, J. C., Abraham, R. T.

Publikováno v: The EMBO Journal; October 1996, Vol. 15 Issue: 19 p5256-5267, 12p

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The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus.

Autor: Brunn, G J, Fadden, P, Haystead, T A, Lawrence, J C

Publikováno v: Journal of Biological Chemistry; December 1997, Vol. 272 Issue: 51 p32547-50, 4p

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Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells.

Autor: Sabers, C J, Martin, M M, Brunn, G J, Williams, J M, Dumont, F J, Wiederrecht, G, Abraham, R T

Publikováno v: Journal of Biological Chemistry; January 1995, Vol. 270 Issue: 2 p815-22, 8p

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Protein-tyrosine kinase-dependent activation of STAT transcription factors in interleukin-2- or interleukin-4-stimulated T lymphocytes.

Autor: Brunn, G J, Falls, E L, Nilson, A E, Abraham, R T

Publikováno v: Journal of Biological Chemistry; May 1995, Vol. 270 Issue: 19 p11628-35, 8p

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Reversal of desipramine toxicity in rats using drug-specific antibody Fab' fragment: effects on hypotension and interaction with sodium bicarbonate.

Autor: Brunn, G J, Keyler, D E, Pond, S M, Pentel, P R

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; March 1992, Vol. 260 Issue: 3 p1392-1399, 8p

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Insulin signaling and the control of PHAS-I phosphorylation.

Autor: Lawrence JC Jr; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia 22908-0735, USA., Brunn GJ

Publikováno v: Progress in molecular and subcellular biology [Prog Mol Subcell Biol] 2001; Vol. 26, pp. 1-31.

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Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.

Autor: Mothe-Satney I; Departments of Pharmacology and Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA., Brunn GJ, McMahon LP, Capaldo CT, Abraham RT, Lawrence JC Jr

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2000 Oct 27; Vol. 275 (43), pp. 33836-43.

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