Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Brunella Costanza"'
Autor:
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra Bianchi, Marc Thiry, Koji Uchida, David A Spiegel, James R Cochrane, Craig A Hutton, Edwin De Pauw, Philippe Delvenne, Dominique Belpomme, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/dfea8585ba3b4458899254c8dcbe41ae
Autor:
Gilles Rademaker, Brunella Costanza, Justine Bellier, Michael Herfs, Raphaël Peiffer, Ferman Agirman, Naïma Maloujahmoum, Yvette Habraken, Philippe Delvenne, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/3c391d5f130d4134b472946773f3313a
Autor:
Gilles Rademaker, Brunella Costanza, Sébastien Pyr dit Ruys, Raphaël Peiffer, Ferman Agirman, Naïma Maloujahmoum, Didier Vertommen, Andrei Turtoi, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-10 (2022)
Abstract Introduction Colorectal cancer remains a public health issue and most colon cancer patients succumb to the development of metastases. Using a specific protocol of pressure-assisted interstitial fluid extrusion to recover soluble biomarkers,
Externí odkaz:
https://doaj.org/article/5b80583472704744baf80c789846d166
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://doaj.org/article/96932a30ac1e4a57b60f7bff8ef7fecf
Autor:
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra Bianchi, Marc Thiry, Koji Uchida, David A Spiegel, James R Cochrane, Craig A Hutton, Edwin De Pauw, Philippe Delvenne, Dominique Belpomme, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
eLife, Vol 5 (2016)
Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins to form advanced glycation end products (AGEs). We have recently demonstrated that MG-induced AG
Externí odkaz:
https://doaj.org/article/2e16f962425e42da9c3a326900bb4ea8
Autor:
Pamela Maris, Arnaud Blomme, Ana Perez Palacios, Brunella Costanza, Akeila Bellahcène, Elettra Bianchi, Stephanie Gofflot, Pierre Drion, Giovanna Elvi Trombino, Emmanuel Di Valentin, Pino G Cusumano, Sylvie Maweja, Guy Jerusalem, Philippe Delvenne, Eric Lifrange, Vincent Castronovo, Andrei Turtoi
Publikováno v:
PLoS Medicine, Vol 12, Iss 9, p e1001871 (2015)
BackgroundBreast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-β1 has been identified as a key driving force behind metastatic breast cancer, with
Externí odkaz:
https://doaj.org/article/c77de1903e044098ad1b63fcaa8b0077
Autor:
Akeila Bellahcene, Roberto Ronca, Guillaume Belthier, Patrick Balaguer, Simon Lacroix, Paola Chiodelli, Gaetan Van Simaeys, Andrei Turtoi, Barbara Chiavarina, Julie Pannequin, Olivier Detry, Guy Jerusalem, Serge Goldman, Stéphanie Gofflot, Arnaud Blomme, Eric Fabbrizio, Sara Rezzola, Gilles Doumont, Ambre Giguelay, Bilguun Erkhem-Ochir, Takehiko Yokobori, Vincent Castronovo, Brunella Costanza, Philippe Delvenne, Vincent Cavaillès, Emmanuel Di Valentin
Publikováno v:
Theranostics
Theranostics, 11 (4
Theranostics, Ivyspring International Publisher, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 11 (4
Theranostics, Ivyspring International Publisher, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Colorectal cancer (CRC) cells are traditionally considered unresponsive to TGFβ due to mutations in the receptors and/or downstream signaling molecules. TGFβ influences CRC cells only indirectly via stromal cells, such as cancer-associated fibrobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e9c7e07d3bd95c7beefaf9ee1bc4f3
https://doi.org/10.7150/thno.51507
https://doi.org/10.7150/thno.51507
Autor:
Stefania Faletti, Daniela Osti, Elena Ceccacci, Cristina Richichi, Brunella Costanza, Luciano Nicosia, Roberta Noberini, Giulia Marotta, Laura Furia, Mario R. Faretta, Silvia Brambillasca, Micaela Quarto, Luca Bertero, Renzo Boldorini, Bianca Pollo, Sara Gandini, Davide Cora, Saverio Minucci, Ciro Mercurio, Mario Varasi, Tiziana Bonaldi, Giuliana Pelicci
Glioblastoma (GBM) is a fatal tumor whose aggressiveness, heterogeneity, poor blood-brain barrier penetration, and resistance to therapy highlight the need for new targets and clinical treatments. A step toward clinical translation includes the eradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e2f7830241c5538a5f4d06d76d06db
http://hdl.handle.net/2318/1861687
http://hdl.handle.net/2318/1861687
Publikováno v:
Cancer and Metastasis Reviews. 37:125-145
The discovery of biomarkers able to detect cancer at an early stage, to evaluate its aggressiveness, and to predict the response to therapy remains a major challenge in clinical oncology and precision medicine. In this review, we summarize recent ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc719efdce0b31d31184ed87370e5ed
https://doi.org/10.1007/s10555-017-9710-0
https://doi.org/10.1007/s10555-017-9710-0
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, 30(5), 1400-1416.e6. Cell Press
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::11eead07678672c11d9b92e97a445f08
https://pubmed.ncbi.nlm.nih.gov/32023458
https://pubmed.ncbi.nlm.nih.gov/32023458