Desmoplakin mutations in cardiac fibroblasts cause TGFβ1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation.

Autor: Wei C, Chan SF, Saguner AM, Brunckhorst C, Duru F, Marine JE, James CA, Calkins H, Judge DP, Shou W, Chen HV

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 09. Date of Electronic Publication: 2024 Sep 09.

Right heart strain in arrhythmogenic right ventricular cardiomyopathy: implications for cardiovascular outcome.

Autor: Anwer S; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland., Stollenwerk L; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Department of Cardiology, Bern University Hospital, Bern, Switzerland., Winkler NE; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland., Guastafierro F; Humanitas Research Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy., Hebeisen M; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Department of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Akdis D; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland.; Division of Cardiology, GZO Zurich Regional Health Center Wetzikon, Wetzikon, Switzerland., Saguner AM; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland., Brunckhorst C; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland., Duru F; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland., Tanner FC; Department of Cardiology, University Heart Center, University Hospital Zürich and University of Zürich, Raemistrasse 100, 8091 Zürich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), University Hospital Zürich and University of Zürich, Wagistrasse 12, 8952 Schlieren, Zürich, Switzerland.

Publikováno v: European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2024 Jul 31; Vol. 25 (8), pp. 1061-1068.

[Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X].

Autor: Hametner G; Kardio Glattal AG, Dübendorf., Osranek M; Kardio Glattal AG, Dübendorf., Brunckhorst C; Universitätsspital Zürich, Klinik für Kardiologie, Zürich., Domingo AM; SwissDNAnalysis, Dübendorf.

Publikováno v: Praxis [Praxis (Bern 1994)] 2024 Feb; Vol. 113 (2), pp. 50-54.

Catecholaminergic Polymorphic Ventricular Tachycardia: Multiple Clinical Presentations of a Genetically Determined Disease.

Autor: Jurisic S; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland., Medeiros-Domingo A; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.; Cardiogenetics-Swiss DNAlysis, 8600 Dubendorf, Switzerland., Berger F; Divison of Pediatric Cardiology, Pediatric Heart Center, Department of Surgery, University Children's Hospital Zurich, 8032 Zurich, Switzerland.; Children's Research Center, University Children's Hospital Zurich, 8032 Zurich, Switzerland., Balmer C; Divison of Pediatric Cardiology, Pediatric Heart Center, Department of Surgery, University Children's Hospital Zurich, 8032 Zurich, Switzerland.; Children's Research Center, University Children's Hospital Zurich, 8032 Zurich, Switzerland., Brunckhorst C; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland., Ruschitzka F; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Saguner AM; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Duru F; Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.; Center for Integrative Human Physiology, University of Zurich, 8091 Zurich, Switzerland.

Publikováno v: Journal of clinical medicine [J Clin Med] 2023 Dec 21; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 21.

Evolution and triggers of defibrillator shocks in patients with arrhythmogenic right ventricular cardiomyopathy.

Autor: Molitor N; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland nadine.molitor@usz.ch ardan.saguner@usz.ch., Hofer D; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Çimen T; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Gasperetti A; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, US., Akdis D; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.; Division of Cardiology, GZO - Regional Health Center, Wetzikon, Switzerland., Costa S; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Jenni R; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Breitenstein A; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Wolber T; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.; Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland., Winnik S; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Fokstuen S; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.; Genetic Medicine division, Diagnostic Department, Hôpitaux Universitaires de Genève, Genève, Switzerland., Fu G; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Medeiros-Domingo A; Swiss DNAlysis Dübendorf, Zurich, Switzerland., Ruschitzka F; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Brunckhorst C; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland., Duru F; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.; Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland., Saguner AM; Cardiology, Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland nadine.molitor@usz.ch ardan.saguner@usz.ch.

Publikováno v: Heart (British Cardiac Society) [Heart] 2023 Jul 12; Vol. 109 (15), pp. 1146-1152. Date of Electronic Publication: 2023 Jul 12.