Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bruna Selbach"'
Autor:
Robert S. Jansen, Lungelo Mandyoli, Ryan Hughes, Shoko Wakabayashi, Jessica T. Pinkham, Bruna Selbach, Kristine M. Guinn, Eric J. Rubin, James C. Sacchettini, Kyu Y. Rhee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Gene rv3722c is essential for in vitro growth of Mycobacterium tuberculosis, but its function is unclear. Here, Jansen et al. show that Rv3722c is the primary aspartate aminotransferase of this pathogen, mediates nitrogen distribution, and is importa
Externí odkaz:
https://doaj.org/article/0694e638b1514ac5a6f5150aca969407
Autor:
Lungelo Mandyoli, Kristine M. Guinn, Robert S. Jansen, Jessica T. Pinkham, Ryan N. Hughes, Bruna Selbach, Kyu Y. Rhee, James C. Sacchettini, Eric J. Rubin, Shoko Wakabayashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Gene rv3722c of Mycobacterium tuberculosis is essential for in vitro growth, and encodes a putative pyridoxal phosphate-binding protein of unknown function. Here we use metabolomic, genetic and structural approaches to show that Rv3722c is the primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f73bc34592c63ca7482434829404fc
https://doaj.org/article/0694e638b1514ac5a6f5150aca969407
https://doaj.org/article/0694e638b1514ac5a6f5150aca969407
Autor:
Lungelo Mandyoli, Kyu Y. Rhee, Weizhen Xu, Bruna Selbach, James C. Sacchettini, Katherine A. Black, Lijun Duan, Sabine Ehrt
Publikováno v:
The Journal of Experimental Medicine
Despite diversification into biochemically distinct enzyme families, rv0812 encodes a single active site that functions as an enzymatically bifunctional aminodeoxychorismate lyase (ADCL) and D–amino acid transaminase (DAAT) and may couple replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd103107cfa59cc81c27bf25e2c2fd3
https://doi.org/10.1084/jem.20191957
https://doi.org/10.1084/jem.20191957
Autor:
Jessica T. Pinkham, Lungelo Mandyoli, Shoko Wakabayashi, Kristine M. Guinn, Bruna Selbach, Eric J. Rubin, Robert S. Jansen, James C. Sacchettini, Ryan N. Hughes, Kyu Y. Rhee
Organisms are defined by their genomes, yet many distinguishing features of a given organism are encoded by genes that are functionally unannotated.Mycobacterium tuberculosis(Mtb), the leading cause of death due to a single microbe, co-evolved with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0498e1867b16b43819c6f02b1dfaf87
https://doi.org/10.1101/784462
https://doi.org/10.1101/784462
