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Akademický článek

Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants

Autor: Angela Maria Moro, Elisa Sauer, Natália Brucker, Mariele Feiffer Charão, Bruna Gauer, Sabrina Nunes do Nascimento, Gabriela Goethel, Marta Maria Medeiros Frescura Duarte, Solange Cristina Garcia

Publikováno v: BMC Pharmacology and Toxicology, Vol 20, Iss S1, Pp 1-9 (2019)

Abstract Background Gasoline is a complex mixture of saturated and unsaturated hydrocarbons, in which aromatic compounds, such as BTX (benzene, toluene, and xylene) feature as the main constituents. Simultaneous exposure to these aromatic hydrocarbon

Externí odkaz: https://doaj.org/article/85e204d0d1b643dc91e82ffed0d5e292

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Antiproliferative activity and toxicity evaluation of 1,2,3-triazole and 4-methyl coumarin hybrids in the MCF7 breast cancer cell line

Autor: Lucas Volnei Augsten, Gabriela Göethel, Bruna Gauer, Mariele Feiffer Charão, Gilsane von Poser, Romulo F. S. Canto, Marcelo Dutra Arbo, Vera Lucia Eifler-Lima, Solange Cristina Garcia

Publikováno v: RSC Medicinal Chemistry. 14:869-879

Coumarin–triazole hybrids went through antitumor activity screening, finding anti-breast cancer cell line MCF7 activity, besides antioxidant activity, mitochondrial membrane disruption and no DNA damage.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f927350df0f962bc626d5b85e00ad24
https://doi.org/10.1039/d3md00031a

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Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage

Autor: Bruna Gauer, Natália Brucker, Elisa Sauer, Caroline Peruzzi, Sabrina Nascimento, Ingrid Flesch, Solange Cristina Garcia, Larissa Cestonaro, Gabriela Göethel, Emanuela Fernanda Tureta, Tatiana D. Saint’ Pierre, Adriana Gioda

Publikováno v: Biological trace element research. 200(8)

Rural children are exposed to several chemicals. This study evaluated the environmental co-exposure of rural children to cholinesterase inhibitor insecticides and metals/metalloids, and the resulting oxidative stress and DNA damage. Seventy-two child

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f95ab82f9de3efb1e05dcd7b7c1f0f7
https://pubmed.ncbi.nlm.nih.gov/34668114

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Biochemical, hematological and immunological parameters and relationship with occupational exposure to pesticides and metals

Autor: Jessica Nardi, Sabrina Nascimento, Solange Cristina Garcia, Tatiana D. Saint'Pierre, Larissa Cestonaro, Bruna Gauer, Gabriela Göethel, Rafael Christian Chávez Rocha, Yasmin Piton, Nuryan Fão, Wesley V. Braga, Elisa Sauer, Adriana Gioda, Caroline Peruzzi, Marcelo Dutra Arbo

Publikováno v: Environmental science and pollution research international. 27(23)

This study aimed to evaluate biomarkers of exposure to cholinesterase inhibitors insecticides (AChE and BuChE activities) and metals (As, Cd, Cr, Mn, Ni, and Pb blood levels) and their associations with biochemical, hematological, and immunological p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd949f5369477f6080f006d2033fd54
https://pubmed.ncbi.nlm.nih.gov/32436094

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Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants

Autor: Bruna Gauer, Marta M.M.F. Duarte, Angela M. Moro, Gabriela Göethel, Sabrina Nascimento, Mariele Feiffer Charão, Solange Cristina Garcia, Natália Brucker, Elisa Sauer

Publikováno v: BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 20, Iss S1, Pp 1-9 (2019)

Background Gasoline is a complex mixture of saturated and unsaturated hydrocarbons, in which aromatic compounds, such as BTX (benzene, toluene, and xylene) feature as the main constituents. Simultaneous exposure to these aromatic hydrocarbons causes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c6607126fe3156ddcf193df1f2bd99
http://europepmc.org/articles/PMC6921377

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Are metals and pyrene levels additional factors playing a pivotal role in air pollution-induced inflammation in taxi drivers?

Autor: Natália Brucker, Marcelo Dutra Arbo, Anelise Barth, Bruna Gauer, Jessica Nardi, Adriana Gioda, Flávia Valladão Thiesen, Solange Cristina Garcia

Publikováno v: Toxicology Research. 7:8-12

This study aimed to evaluate which xenobiotic (As, Hg, Pb or pyrenes) is primarily responsible for the inflammatory process in taxi drivers. Multiple regression analysis showed that Hg is the main xenobiotic responsible for the increase of cytokine l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17de811ec25233c4ad16b1822263e0af
https://doi.org/10.1039/c7tx00203c

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Biomonitoring of gasoline station attendants exposed to benzene: Effect of gender

Autor: Anelise Barth, Adriana Gioda, Elisa Sauer, Bruna Gauer, Marília Baierle, Sabrina Nascimento, Gabriela Göethel, Beatriz Silva Amaral, Juliano Durgante, Mariele Feiffer Charão, Solange Cristina Garcia, Francisco Radler de Aquino Neto, Natália Brucker, Angela M. Moro

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 813:1-9

Women are employed in increasing numbers as gasoline station attendants, a work category with risk of exposure to benzene. We have assessed the effect of gender on biomarkers of occupational benzene exposure. Gasoline station attendants (20 men and 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a116b2c3c6b06c144ebe9cb4dc85bfa
https://doi.org/10.1016/j.mrgentox.2016.11.002

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Cellular response to chemicals present in air pollution in occupationally exposed workers and its potential cancer susceptibility

Autor: Ingrid Flesch, Elisa Sauer, Natália Brucker, Adriana Gioda, Bruna Gauer, Tatiana Sant'Pierre, Nuryan Fão, Caroline Peruzzi, Solange Cristina Garcia, Larissa Cestonaro, Ursula da Silveira Matte, Sabrina Nascimento, Gabriela Göethel

Publikováno v: Chemosphere. 263:127857

The study aimed to evaluate the potential effects of the chronic exposure to chemical agents from air pollution on phenotypic and genotypic expressions of peripheral biomarkers and tumor-related proteins in mononuclear cells. This study evaluates 85

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1546e490ed8d86d0931f088fd2b5270d
https://doi.org/10.1016/j.chemosphere.2020.127857

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Inflammatory and oxidative stress biomarkers at protein and molecular levels in workers occupationally exposed to crystalline silica

Autor: Daniela Gnoatto, Gabriela Göethel, Jorge Souza, Elisa Sauer, Nuryan Fão, Jessica Nardi, Solange Cristina Garcia, Larissa Cestonaro, Caroline Peruzzi, Sabrina Nascimento, Bruna Gauer, Shanda Cattani, Cristiane Paim

Publikováno v: Environmental science and pollution research international. 26(2)

Workers chronically exposed to respirable crystalline silica (CS) are susceptible to adverse health effects like silicosis and lung cancer. This study aimed to investigate potential early peripheral biomarkers of inflammation and oxidative stress in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8ec7dc3a4dc4dad1dce3638fb5040f
https://pubmed.ncbi.nlm.nih.gov/30426371

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