CAR T Cells and T-Cell Therapies for Cancer: A Translational Science Review.

Autor: Brudno JN; Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Maus MV; Department of Medicine, Massachusetts General Hospital Cancer Center, Boston., Hinrichs CS; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick.

Publikováno v: JAMA [JAMA] 2024 Nov 04. Date of Electronic Publication: 2024 Nov 04.

CAR T-cell therapy comes of age: Introductory editorial for the special issue.

Autor: Brudno JN

Publikováno v: Seminars in hematology [Semin Hematol] 2024 Oct; Vol. 61 (5), pp. 271-272.

Current understanding and management of CAR T cell-associated toxicities.

Autor: Brudno JN; Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. jennifer.brudno@nih.gov., Kochenderfer JN; Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Publikováno v: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2024 Jul; Vol. 21 (7), pp. 501-521. Date of Electronic Publication: 2024 May 20.

Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain.

Autor: Mikkilineni L; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Natrakul DA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lam N; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Manasanch EE; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mann J; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Weissler KA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Wong N; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research in the CCR Collaborative Bioinformatics Resource, National Cancer Institute, Bethesda, MD, USA., Brudno JN; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Goff SL; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yang JC; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ganaden M; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Patel R; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Zheng Z; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Gartner JJ; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Martin KR; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Wang HW; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yuan CM; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lowe T; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Maric I; Hematology Service, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD, USA., Shao L; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Jin P; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Stroncek DF; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Highfill SL; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Rosenberg SA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kochenderfer JN; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: kochendj@mail.nih.gov.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Feb 07; Vol. 32 (2), pp. 503-526. Date of Electronic Publication: 2023 Dec 28.

Off-the-shelf CAR T cells for multiple myeloma.

Autor: Brudno JN; Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. jennifer.brudno@nih.gov., Kochenderfer JN; Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Publikováno v: Nature medicine [Nat Med] 2023 Feb; Vol. 29 (2), pp. 303-304.