Zobrazeno 1 - 10 of 57 pro vyhledávání: '"Bruchhaus J"'
1
Akademický článek
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Autor: Wilding B; Boehringer Ingelheim RCV, Vienna, Austria. birgit.wilding@boehringer-ingelheim.com., Scharn D; Boehringer Ingelheim RCV, Vienna, Austria., Böse D; Boehringer Ingelheim RCV, Vienna, Austria., Baum A; Boehringer Ingelheim RCV, Vienna, Austria., Santoro V; Boehringer Ingelheim RCV, Vienna, Austria., Chetta P; Boehringer Ingelheim RCV, Vienna, Austria., Schnitzer R; Boehringer Ingelheim RCV, Vienna, Austria., Botesteanu DA; Boehringer Ingelheim RCV, Vienna, Austria., Reiser C; Boehringer Ingelheim RCV, Vienna, Austria., Kornigg S; Boehringer Ingelheim RCV, Vienna, Austria., Knesl P; Boehringer Ingelheim RCV, Vienna, Austria., Hörmann A; Boehringer Ingelheim RCV, Vienna, Austria., Köferle A; Boehringer Ingelheim RCV, Vienna, Austria., Corcokovic M; Boehringer Ingelheim RCV, Vienna, Austria., Lieb S; Boehringer Ingelheim RCV, Vienna, Austria., Scholz G; Boehringer Ingelheim RCV, Vienna, Austria., Bruchhaus J; Boehringer Ingelheim RCV, Vienna, Austria., Spina M; Boehringer Ingelheim RCV, Vienna, Austria., Balla J; Boehringer Ingelheim RCV, Vienna, Austria., Peric-Simov B; Boehringer Ingelheim RCV, Vienna, Austria., Zimmer J; Boehringer Ingelheim RCV, Vienna, Austria., Mitzner S; Boehringer Ingelheim RCV, Vienna, Austria., Fett TN; Boehringer Ingelheim RCV, Vienna, Austria., Beran A; Boehringer Ingelheim RCV, Vienna, Austria., Lamarre L; Boehringer Ingelheim RCV, Vienna, Austria., Gerstberger T; Boehringer Ingelheim RCV, Vienna, Austria., Gerlach D; Boehringer Ingelheim RCV, Vienna, Austria., Bauer M; Boehringer Ingelheim RCV, Vienna, Austria., Bergner A; Boehringer Ingelheim RCV, Vienna, Austria., Schlattl A; Boehringer Ingelheim RCV, Vienna, Austria., Bader G; Boehringer Ingelheim RCV, Vienna, Austria., Treu M; Boehringer Ingelheim RCV, Vienna, Austria., Engelhardt H; Boehringer Ingelheim RCV, Vienna, Austria., Zahn S; Boehringer Ingelheim RCV, Vienna, Austria., Fuchs JE; Boehringer Ingelheim RCV, Vienna, Austria., Zuber J; Institute of Molecular Pathology (IMP), Vienna, Austria.; Medical University of Vienna, Vienna, Austria., Ettmayer P; Boehringer Ingelheim RCV, Vienna, Austria., Pearson M; Boehringer Ingelheim RCV, Vienna, Austria., Petronczki M; Boehringer Ingelheim RCV, Vienna, Austria., Kraut N; Boehringer Ingelheim RCV, Vienna, Austria., McConnell DB; Boehringer Ingelheim RCV, Vienna, Austria., Solca F; Boehringer Ingelheim RCV, Vienna, Austria. flavio.solca@boehringer-ingelheim.com., Neumüller RA; Boehringer Ingelheim RCV, Vienna, Austria. ralph.neumueller@boehringer-ingelheim.com.
Publikováno v: Nature cancer [Nat Cancer] 2022 Jul; Vol. 3 (7), pp. 821-836. Date of Electronic Publication: 2022 Jul 26.
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2
Akademický článek
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based Methods.
Autor: Kessler D; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Mayer M; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Zahn SK; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Zeeb M; Boehringer Ingelheim Pharma GmbH & Co KG, Birkendorfer Straße 65, 88397, Biberach, Germany., Wöhrle S; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Bergner A; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Bruchhaus J; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Ciftci T; Boehringer Ingelheim Pharma GmbH & Co KG, Birkendorfer Straße 65, 88397, Biberach, Germany., Dahmann G; Boehringer Ingelheim Pharma GmbH & Co KG, Birkendorfer Straße 65, 88397, Biberach, Germany., Dettling M; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Döbel S; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Fuchs JE; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Geist L; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Hela W; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Kofink C; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Kousek R; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Moser F; Boehringer Ingelheim Pharma GmbH & Co KG, Birkendorfer Straße 65, 88397, Biberach, Germany., Puchner T; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Rumpel K; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Scharnweber M; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Werni P; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Wolkerstorfer B; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Breitsprecher D; NanoTemper Technologies GmbH, Floessergasse 4, 81369, Muenchen, Germany.; Leica Microsystems AG, Max Schmidheiny-Strasse 201, 9435, Heerbrugg, Switzerland., Baaske P; NanoTemper Technologies GmbH, Floessergasse 4, 81369, Muenchen, Germany., Pearson M; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., McConnell DB; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria., Böttcher J; Boehringer Ingelheim RCV GmbH & Co KG, Dr.-Boehringer-Gasse 5-11, 1121, Vienna, Austria.
Publikováno v: ChemMedChem [ChemMedChem] 2021 May 06; Vol. 16 (9), pp. 1420-1424. Date of Electronic Publication: 2021 Jan 14.
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4
Akademický článek
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.
Autor: Weinstabl H; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Treu M; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Rinnenthal J; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Zahn SK; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Ettmayer P; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Bader G; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Dahmann G; Boehringer Ingelheim Pharma GmbH & Co. KG , Birkendorfer Str. 65 , 88400 Biberach an der Riß , Germany., Kessler D; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Rumpel K; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Mischerikow N; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Savarese F; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Gerstberger T; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Mayer M; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Zoephel A; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Schnitzer R; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Sommergruber W; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Martinelli P; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Arnhof H; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Peric-Simov B; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Hofbauer KS; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Garavel G; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Scherbantin Y; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Mitzner S; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Fett TN; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Scholz G; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Bruchhaus J; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Burkard M; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Kousek R; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Ciftci T; Boehringer Ingelheim Pharma GmbH & Co. KG , Birkendorfer Str. 65 , 88400 Biberach an der Riß , Germany., Sharps B; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Schrenk A; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Harrer C; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Haering D; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Wolkerstorfer B; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Zhang X; Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China., Lv X; Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China., Du A; Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China., Li D; Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China., Li Y; Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China., Quant J; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., Pearson M; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria., McConnell DB; Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2019 Sep 12; Vol. 62 (17), pp. 7976-7997. Date of Electronic Publication: 2019 Aug 14.
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5
Akademický článek
Synthesis of novel pyrimido[4,5‐b]quinolines as potential anticancer agents and HER2 inhibitors.
Autor: Ibrahim, Nahla Said M.1 (AUTHOR) nahla.ibrahim@pharma.cu.edu.eg, Kadry, Hanan H.1 (AUTHOR), Zaher, Ashraf F.1 (AUTHOR), Mohamed, Khaled O.1 (AUTHOR) khaled.mohamed@pharma.cu.edu.eg
Publikováno v: Chemical Biology & Drug Design. Nov2023, Vol. 102 Issue 5, p996-1013. 18p.
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6
Akademický článek
Sesquiterpene Coumarin Ethers with Selective Cytotoxic Activities from the Roots of Ferula huber-morathii Peşmen (Apiaceae) and Unequivocal Determination of the Absolute Stereochemistry of Samarcandin.
Autor: Eruçar, Fatma Memnune1 (AUTHOR) memnune.erucar@istanbul.edu.tr, Kuran, Fadıl Kaan1 (AUTHOR) kaankuran@istanbul.edu.tr, Altıparmak Ülbegi, Gülsüm2 (AUTHOR) gulsum.altiparmakulbegi@istanbul.edu.tr, Özbey, Süheyla3 (AUTHOR) sozbey@hacettepe.edu.tr, Karavuş, Şule Nur4 (AUTHOR) sule.karavus@medipol.edu.tr, Arcan, Gülşah Gamze2 (AUTHOR) gamze.arcan@istanbul.edu.tr, Yazıcı Tütüniş, Seçil1 (AUTHOR) secilyaz@istanbul.edu.tr, Tan, Nur1 (AUTHOR) nurtan@istanbul.edu.tr, Aksoy Sağırlı, Pınar2 (AUTHOR) aksoyp@istanbul.edu.tr, Miski, Mahmut1 (AUTHOR) mahmut.miski@gmail.com
Publikováno v: Pharmaceuticals (14248247). Jun2023, Vol. 16 Issue 6, p792. 27p.
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7
Akademický článek
Array of Nanopore Sensors Detect Nanoscale Biomolecules by Nucleic Acid Analysis.
Autor: Ma, Jingchen1,2 (AUTHOR), Ji, Weiwei3 (AUTHOR), Song, Xin4 (AUTHOR) runzheng0314@163.com, Feng, Silu1,2 (AUTHOR) siluf1230@163.com
Publikováno v: ChemistrySelect. 5/5/2023, Vol. 8 Issue 17, p1-19. 19p.
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8
Akademický článek
Phytochemical, Antimicrobial, Antioxidant, and In Vitro Cytotoxicity Evaluation of Echinops erinaceus Kit Tan.
Autor: Sweilam, Sherouk Hussein1,2 (AUTHOR), Abdel Bar, Fatma M.1,3 (AUTHOR), Foudah, Ahmed I.1 (AUTHOR), Alqarni, Mohammed H.1 (AUTHOR), Elattal, Nouran A.4 (AUTHOR), El-Gindi, Omayma D.2 (AUTHOR), El-Sherei, Moshera M.5 (AUTHOR), Abdel-Sattar, Essam5 (AUTHOR) essam.abdelsattar@pharma.cu.edu.eg
Publikováno v: Separations (2297-8739). Dec2022, Vol. 9 Issue 12, p447. 18p.
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9
Akademický článek
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10
Akademický článek
Systemic evolutionary chemical space exploration for drug discovery.
Autor: Lu, Chong1 (AUTHOR), Liu, Shien1 (AUTHOR), Shi, Weihua1 (AUTHOR), Yu, Jun1 (AUTHOR), Zhou, Zhou1 (AUTHOR), Zhang, Xiaoxiao1 (AUTHOR), Lu, Xiaoli1 (AUTHOR), Cai, Faji1 (AUTHOR), Xia, Ning2 (AUTHOR), Wang, Yikai1 (AUTHOR) wang_yikai@keenthera.com
Publikováno v: Journal of Cheminformatics. 4/1/2022, Vol. 14 Issue 1, p1-17. 17p.
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