Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bruce Zetter"'
Autor:
Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael S. Rogers, Diane Joseph-McCarthy, Arijit Chakravarty
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The rapid emergence and expansion of novel SARS-CoV-2 variants threatens our ability to achieve herd immunity for COVID-19. These novel SARS-CoV-2 variants often harbor multiple point mutations, conferring one or more evolutionarily advantag
Externí odkaz:
https://doaj.org/article/1e588587b1a248438243cf75bb3474be
Autor:
Debra Van Egeren, Madison Stoddard, Laura F. White, Natasha S. Hochberg, Michael S. Rogers, Bruce Zetter, Diane Joseph-McCarthy, Arijit Chakravarty
Publikováno v:
Vaccines, Vol 11, Iss 4, p 853 (2023)
The rapid emergence of immune-evading viral variants of SARS-CoV-2 calls into question the practicality of a vaccine-only public-health strategy for managing the ongoing COVID-19 pandemic. It has been suggested that widespread vaccination is necessar
Externí odkaz:
https://doaj.org/article/5048dcbdf80f4d8d9efcb34df73c9033
Autor:
Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L Pentelute, Jonathan M Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250780 (2021)
The spike protein receptor-binding domain (RBD) of SARS-CoV-2 is the molecular target for many vaccines and antibody-based prophylactics aimed at bringing COVID-19 under control. Such a narrow molecular focus raises the specter of viral immune evasio
Externí odkaz:
https://doaj.org/article/df07e5ae9e2b41f6a400a2d607fc2dec
Autor:
Debra Van Egeren, Madison Stoddard, Alexander Novokhodko, Michael S Rogers, Diane Joseph-McCarthy, Bruce Zetter, Arijit Chakravarty
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0258997 (2021)
The development and deployment of several SARS-CoV-2 vaccines in a little over a year is an unprecedented achievement of modern medicine. The high levels of efficacy against transmission for some of these vaccines makes it feasible to use them to sup
Externí odkaz:
https://doaj.org/article/e511335d15b14ea08376aac679b5be1b
Autor:
Oliver Kisker, Shinya Onizuka, Christian M. Becker, Michael Fannon, Evelyn Flynn, Robert D'Amato, Bruce Zetter, Judah Folkman, Rahul Ray, Narasimha Swamy, Steven Pirie-Shepherd
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 1, Pp 32-40 (2003)
We have isolated a selectively deglycosylated form of vitamin D binding protein (DBP-maf) generated from systemically available DBP by a human pancreatic cancer cell line. DBP-maf is anti proliferative for endothelial cells and antiangiogenic in the
Externí odkaz:
https://doaj.org/article/5730b41e7d904f80980dd950bf8f2362
Autor:
Madison Stoddard, Alexander Novokhodko, Sharanya Sarkar, Debra Van Egeren, Laura F. White, Natasha S. Hochberg, Michael S. Rogers, Bruce Zetter, Diane Joseph-McCarthy, Arijit Chakravarty
Publikováno v:
COVID; Volume 2; Issue 12; Pages: 1689-1709
We have entered a new phase of the ongoing COVID-19 pandemic, as the strategy of relying solely on the current SARS-CoV-2 vaccines to bring the pandemic to an end has become infeasible. In response, public-health authorities in many countries have ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c915ef2d468ac981ec4c70b7297baa97
https://doi.org/10.3390/covid2120121
https://doi.org/10.3390/covid2120121
Inhibition of Wnt Signaling in Colon Cancer Cells via an Oral Drug that Facilitates TNIK Degradation
Autor:
Kun Zhou, Jae Eun Cheong, Subrahmanian Tarakkad Krishnaji, Aram Ghalali, Haojie Fu, Lufei Sui, Catherine Alix-Panabières, Laure Cayrefourcq, Diane Bielenberg, Lijun Sun, Bruce Zetter
Publikováno v:
Molecular Cancer Therapeutics. 22:25-36
We have synthesized an oxetane derivative of the benzimidazole compound mebendazole (OBD9) with enhanced solubility and strong anticancer activity in multiple types of cancer cells, especially colorectal cancer. In this report, we provide evidence th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a8786e39f36a603ba5eba0eed6d9e5
https://doi.org/10.1158/1535-7163.mct-21-0801
https://doi.org/10.1158/1535-7163.mct-21-0801
Autor:
Bruce Zetter, Lijun Sun, Diane Bielenberg, Laure Cayrefourcq, Catherine Alix-Panabières, Lufei Sui, Haojie Fu, Aram Ghalali, Subrahmanian Tarakkad Krishnaji, Jae Eun Cheong, Kun Zhou
Supplementary figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c616bcaed3c20f70c10ba6d27b6f683
https://doi.org/10.1158/1535-7163.22523335
https://doi.org/10.1158/1535-7163.22523335
Autor:
Debra Van Egeren, Madison Stoddard, Laura F. White, Natasha S. Hochberg, Michael S. Rogers, Bruce Zetter, Diane Joseph-McCarthy, Arijit Chakravarty
Publikováno v:
Vaccines; Volume 11; Issue 4; Pages: 853
The rapid emergence of immune-evading viral variants of SARS-CoV-2 calls into question the practicality of a vaccine-only public health strategy for managing the ongoing COVID-19 pandemic. It has been suggested that widespread vaccination is necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bb9b9eca029dc7ae2adcbe79f3705d
https://doi.org/10.1101/2022.10.04.22280696
https://doi.org/10.1101/2022.10.04.22280696
Publikováno v:
Cancer Research. 79:14-14
Metastatic cancers account for the great majority of cancer deaths. We conducted a screen to indetify known drugs that selectively inhibit the viability of metastatic tumor cells. Results of the screen identified members of the FDA-approved benzimida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e91aecf1576ce471e589858fe3dd8b
https://doi.org/10.1158/1538-7445.am2019-14
https://doi.org/10.1158/1538-7445.am2019-14