Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Bruce W. Kirkham"'
Autor:
Bruce W. Kirkham, Alexander Egeberg, Frank Behrens, Andreas Pinter, Joseph F. Merola, Thorsten Holzkämper, Gaia Gallo, Khai Jing Ng, Rebecca Bolce, Christopher Schuster, Peter Nash, Luis Puig
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 5, Pp 1127-1146 (2023)
Abstract Nail psoriasis is a difficult-to-treat manifestation of psoriatic disease affecting up to 80% of patients with psoriatic arthritis (PsA) and 40–60% of patients with plaque psoriasis (PsO). Ixekizumab (IXE), a high-affinity monoclonal antib
Externí odkaz:
https://doaj.org/article/4c9392c1257a45e0b15c5bcafb3f3df9
Autor:
Giovanni A.M. Povoleri, Lucy E. Durham, Elizabeth H. Gray, Sylvine Lalnunhlimi, Shichina Kannambath, Michael J. Pitcher, Pawan Dhami, Thomas Leeuw, Sarah E. Ryan, Kathryn J.A. Steel, Bruce W. Kirkham, Leonie S. Taams
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112514- (2023)
Summary: CD69+CD103+ tissue-resident memory T (TRM) cells are important drivers of inflammation. To decipher their role in inflammatory arthritis, we apply single-cell, high-dimensional profiling to T cells from the joints of patients with psoriatic
Externí odkaz:
https://doaj.org/article/7c887f70768745f6826a22484fb9b917
Autor:
Nicola J. Gullick, Fowzia Ibrahim, Ian C. Scott, Alexandra Vincent, Andrew P. Cope, Toby Garrood, Gabriel S. Panayi, David L. Scott, Bruce W. Kirkham, On behalf of TITRATE Programme Investigators
Publikováno v:
BMC Rheumatology, Vol 3, Iss 1, Pp 1-10 (2019)
Abstract Background The emphasis on treating rheumatoid arthritis (RA) intensively reduces disease activity but its impact in routine care is uncertain. We evaluated temporal changes in disease activities and outcomes in a 10-year prospective observa
Externí odkaz:
https://doaj.org/article/5ed2d01ef5e44e2386a0fa67a88ad154
Autor:
Ernest Choy, Xenofon Baraliakos, Frank Behrens, Salvatore D’Angelo, Kurt de Vlam, Bruce W. Kirkham, Mikkel Østergaard, Georg A. Schett, Michael Rissler, Kamel Chaouche-Teyara, Chiara Perella
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-6 (2019)
Abstract Spondyloarthritis comprises a group of inflammatory diseases, characterised by inflammation within axial joints and/or peripheral arthritis, enthesitis and dactylitis. An increasing number of biologic treatments, including biosimilars, are a
Externí odkaz:
https://doaj.org/article/bcfaeb54cfae4cbaa978343733a93070
Autor:
Peter Nash, Luminita Pricop, Bruce W Kirkham, Alexis Ogdie, Effie Pournara, Christopher T Ritchlin, Matthias Kormaksson, Gregory Ligozio
Publikováno v:
RMD Open, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/07fa0ebc62d94151b4fe1e0af203bd1b
Autor:
Frances Humby, Sujith Subesinghe, Andrew Cope, Bina Menon, Rachel Byng-Maddock, Nadia Ladha Hassan, Laura Blackler, Zoe Mckee, Karen Topping, Lydia Marsh, Toby Garrood, Nora Ng, Bruce W Kirkham
Publikováno v:
Rheumatology. 62
Background/Aims In England, patients with rheumatoid arthritis (RA) with Moderate Disease Activity (MDAS), assessed by the DAS28 measure, had been unable to access effective therapies. We and others have reported that this group has persistent active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb85cf5265a0e504bb782a78b48cf05
https://doi.org/10.1093/rheumatology/kead104.326
https://doi.org/10.1093/rheumatology/kead104.326
Autor:
Bruce W Kirkham, Elena Nikiphorou, Christopher J Edwards, Mohamed Sheesh, Ewa Haladyj, Jens Gerwien, Liliana Zaremba-Pechmann, Peter C Taylor
Publikováno v:
Rheumatology. 62
Background/Aims Baricitinib, an oral selective JAK 1/2 inhibitor, is approved for treating adults with moderate-to-severe active rheumatoid arthritis (RA). This analysis aims to report the efficacy of baricitinib in patients with moderate RA at weeks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8148fe85cb97c7882476579e50efdb86
https://doi.org/10.1093/rheumatology/kead104.168
https://doi.org/10.1093/rheumatology/kead104.168
Autor:
Elizabeth H. Gray, Ushani Srenathan, Lucy E. Durham, Sylvine Lalnunhlimi, Kathryn J. A. Steel, Anca Catrina, Bruce W. Kirkham, Leonie S. Taams
IL-17A+ CD8+ T-cells, often referred to as Tc17 cells, have been identified at sites of inflammation in several immune-mediated inflammatory diseases including psoriasis and spondyloarthritis. Whilst much of our understanding of IL-17A+ CD8+ T-cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f85020ba6b65f166f544b8773ae9583
https://doi.org/10.1101/2022.11.14.516164
https://doi.org/10.1101/2022.11.14.516164
Autor:
Zoe Rutter-Locher, Nikita Arumalla, Sam Norton, Leonie S. Taams, Bruce W. Kirkham, Kirsty Bannister
Publikováno v:
Seminars in Arthritis and Rheumatism. 61:152207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3957eed4f4d8a11c1d8de048d3fc4b97
https://doi.org/10.1016/j.semarthrit.2023.152207
https://doi.org/10.1016/j.semarthrit.2023.152207
Autor:
Alan N, Baer, Mara, McAdams DeMarco, Stephen C, Shiboski, Mi Y, Lam, Stephen, Challacombe, Troy E, Daniels, Yi, Dong, John S, Greenspan, Bruce W, Kirkham, Hector E, Lanfranchi, Morten, Schiødt, Muthiah, Srinivasan, Hisanori, Umehara, Frederick B, Vivino, Cristina F, Vollenweider, Yan, Zhao, Lindsey A, Criswell, Caroline H, Shiboski, N, Kalyani
Publikováno v:
Annals of the Rheumatic Diseases. 74:1557-1561
Objective To determine whether the Sjogren9s syndrome B (SSB)-positive/Sjogren9s syndrome A (SSA)-negative antibody profile is associated with key phenotypic features of SS. Methods Among registrants in the Sjogren9s International Collaborative Clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f15ec7a3c21ac13c4ebf86bc4231b8
https://doi.org/10.1136/annrheumdis-2014-206683
https://doi.org/10.1136/annrheumdis-2014-206683