Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Bruce W Kirkham"'
Autor:
Sam Norton, Bruce W Kirkham, James Galloway, Khaldoun Chaabo, Toby Garrood, Zoe Rutter-Locher, Estee Chan, Alex Vincent
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Introduction Despite better therapies and strategies, many people with rheumatoid arthritis (RA) have persistent pain, often from abnormal pain processing, now termed nociplastic pain. However, RA patients with fibromyalgia (FM), a central nociplasti
Externí odkaz:
https://doaj.org/article/9f332f35f41242d5b9cf229f9367f721
Autor:
René E M Toes, Bruce W Kirkham, L A Trouw, Michelle D van den Beukel, Leonie S Taams, Catherine D Hughes, Sarah E Ryan, Kathryn J A Steel, Karin A J van Schie, Bina Menon
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objective Undifferentiated, early inflammatory arthritis (EIA) can differentiate into seropositive or seronegative rheumatoid arthritis (RA), peripheral spondyloarthritis (SpA) or remain as seronegative undifferentiated inflammatory arthritis (UIA).
Externí odkaz:
https://doaj.org/article/1632d54ad26941bea5e5f23ce49f79fa
Autor:
Iain B McInnes, Stefan Siebert, Paul Bowness, Laura C Coates, Anne Francis, Bruce W Kirkham, Alexander Ooms, Hussein Al-Mossawi, Louise Bennett, Nicole Yager, Duncan Richards, Mimi Bogale, Carl Goodyear, Sylvine Lalnunhlimi, Leonie S Taams, Aysin Tulunay Virlan
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction Psoriatic arthritis (PsA) affects around 150 000 people in the UK of whom around 50% require treatment with biologics. The most used biologics for PsA target tumour necrosis factor (TNF) or interleukin-17A (IL-17A). About 50% of patients
Externí odkaz:
https://doaj.org/article/fec1e3e94bdb470b8bf658b6414ae65c
Autor:
Peter Nash, Luminita Pricop, Bruce W Kirkham, Alexis Ogdie, Effie Pournara, Christopher T Ritchlin, Matthias Kormaksson, Gregory Ligozio
Publikováno v:
RMD Open, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/07fa0ebc62d94151b4fe1e0af203bd1b
Autor:
Nicola J Gullick, Hayley G Evans, Leigh D Church, David M Jayaraj, Andrew Filer, Bruce W Kirkham, Leonie S Taams
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12516 (2010)
Power Doppler ultrasound (PDUS) is increasingly used to assess synovitis in Rheumatoid Arthritis (RA). Prior studies have shown correlations between PDUS scores and vessel counts, but relationships with T cell immunopathology have not been described.
Externí odkaz:
https://doaj.org/article/8bf2fbbdb4d44f78b810f2395009b904
Autor:
Nicola J. Gullick, Fowzia Ibrahim, Ian C. Scott, Alexandra Vincent, Andrew P. Cope, Toby Garrood, Gabriel S. Panayi, David L. Scott, Bruce W. Kirkham, On behalf of TITRATE Programme Investigators
Publikováno v:
BMC Rheumatology, Vol 3, Iss 1, Pp 1-10 (2019)
Abstract Background The emphasis on treating rheumatoid arthritis (RA) intensively reduces disease activity but its impact in routine care is uncertain. We evaluated temporal changes in disease activities and outcomes in a 10-year prospective observa
Externí odkaz:
https://doaj.org/article/5ed2d01ef5e44e2386a0fa67a88ad154
Autor:
Bruce W Kirkham, Elena Nikiphorou, Christopher J Edwards, Mohamed Sheesh, Ewa Haladyj, Jens Gerwien, Liliana Zaremba-Pechmann, Peter C Taylor
Publikováno v:
Rheumatology. 62
Background/Aims Baricitinib, an oral selective JAK 1/2 inhibitor, is approved for treating adults with moderate-to-severe active rheumatoid arthritis (RA). This analysis aims to report the efficacy of baricitinib in patients with moderate RA at weeks
Autor:
Frances Humby, Sujith Subesinghe, Andrew Cope, Bina Menon, Rachel Byng-Maddock, Nadia Ladha Hassan, Laura Blackler, Zoe Mckee, Karen Topping, Lydia Marsh, Toby Garrood, Nora Ng, Bruce W Kirkham
Publikováno v:
Rheumatology. 62
Background/Aims In England, patients with rheumatoid arthritis (RA) with Moderate Disease Activity (MDAS), assessed by the DAS28 measure, had been unable to access effective therapies. We and others have reported that this group has persistent active
Autor:
Zoe Rutter-Locher, Nikita Arumalla, Sam Norton, Leonie S. Taams, Bruce W. Kirkham, Kirsty Bannister
Publikováno v:
Seminars in Arthritis and Rheumatism. 61:152207
Autor:
Elizabeth H. Gray, Ushani Srenathan, Lucy E. Durham, Sylvine Lalnunhlimi, Kathryn J. A. Steel, Anca Catrina, Bruce W. Kirkham, Leonie S. Taams
IL-17A+ CD8+ T-cells, often referred to as Tc17 cells, have been identified at sites of inflammation in several immune-mediated inflammatory diseases including psoriasis and spondyloarthritis. Whilst much of our understanding of IL-17A+ CD8+ T-cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f85020ba6b65f166f544b8773ae9583
https://doi.org/10.1101/2022.11.14.516164
https://doi.org/10.1101/2022.11.14.516164