Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bruce Turpie"'
Publikováno v:
BioTechniques, Vol 26, Iss 2, Pp 216-222 (1999)
Externí odkaz:
https://doaj.org/article/5660a9b1ad53489a80a69d093bc288ea
Publikováno v:
Clinical and Experimental Immunology. 188:86-95
Summary Sjögren's syndrome is the second most common rheumatic disease in which autoimmune response targets exocrine glands (salivary and lacrimal glands) result in clinical symptoms of dry mouth and dry eye. Inflammation of the lacrimal gland induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccd81dca7e08ce8b0744f3758f28d6b
https://doi.org/10.1111/cei.12919
https://doi.org/10.1111/cei.12919
Autor:
Bruce Turpie, Sumit Bhattacharya, Robin R. Hodges, Darlene A. Dartt, David E. McNay, Sharmila Masli, Dayu Li, Tor Paaske Utheim, Helen P. Makarenkova, Marie A. Shatos, Rakibul Islam, Masahiro Morinaga
Publikováno v:
Experimental Eye Research. 153:27-41
The purpose of this study was to investigate the changes that occur in the lacrimal glands (LGs) in female thrombospondin 1 knockout (TSP1-/-) mice, a mouse model of the autoimmune disease Sjogren's syndrome. The LGs of 4, 12, and 24 week-old female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95240398408c9ed22d64e9d67b172a06
https://doi.org/10.1016/j.exer.2016.09.011
https://doi.org/10.1016/j.exer.2016.09.011
Autor:
Marie A, Shatos, Robin R, Hodges, Masahiro, Morinaga, David E, McNay, Rakibul, Islam, Sumit, Bhattacharya, Dayu, Li, Bruce, Turpie, Helen P, Makarenkova, Sharmila, Masli, Tor P, Utheim, Darlene A, Dartt
Publikováno v:
Experimental eye research. 153
The purpose of this study was to investigate the changes that occur in the lacrimal glands (LGs) in female thrombospondin 1 knockout (TSP1−/−) mice, a mouse model of the autoimmune disease Sjogren’s syndrome. The LGs of 4, 12, and 24 week-old f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84e44684c64561c73d66f862f902f796
https://pubmed.ncbi.nlm.nih.gov/27697548
https://pubmed.ncbi.nlm.nih.gov/27697548
Publikováno v:
The FASEB Journal. 23:2226-2234
IκBα is an inhibitor of the transcriptional factor NF-κB, and it is an essential component of the signaling pathways that lead to expression of inflammatory molecules. These include cytokines and c...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbfe1d9dd58c39af281cd6eecdad3b1f
https://doi.org/10.1096/fj.08-124545
https://doi.org/10.1096/fj.08-124545
Autor:
Bruce Turpie, Sharmila Masli
Publikováno v:
Immunology. 127:62-72
Exposure of macrophages to transforming growth factor (TGF)-beta is known to alter their functional phenotype such that antigen presentation by these cells leads to tolerance rather than an inflammatory immune response. Typically, eye-derived antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c23d132b0b3ed2b6673a6bbda0020d91
https://doi.org/10.1111/j.1365-2567.2008.02933.x
https://doi.org/10.1111/j.1365-2567.2008.02933.x
Publikováno v:
The Journal of Immunology. 168:2264-2273
APCs deployed within iris/ciliary body are responsible for promoting anterior chamber-associated immune deviation following injection of Ag into the eye. TGFβ-2, a constituent of the ocular microenvironment, converts conventional APCs that are pulse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171053195cb83f4da4f37961e721ec17
https://doi.org/10.4049/jimmunol.168.5.2264
https://doi.org/10.4049/jimmunol.168.5.2264
Publikováno v:
BioTechniques. 26:216-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7437393de20bc88b9d29b5661aae5191
https://doi.org/10.2144/99262bm07
https://doi.org/10.2144/99262bm07
Publikováno v:
The American journal of pathology. 175(3)
Thrombospondin-1 (TSP-1) is a major activator of latent transforming growth factor-beta in vitro as well as in vivo. Mice deficient in TSP-1, despite appearing normal at birth, develop a chronic form of ocular surface disease that is marked by increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40dfe369df8838bec714bc9659114b9
https://pubmed.ncbi.nlm.nih.gov/19700744
https://pubmed.ncbi.nlm.nih.gov/19700744
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(7)
IκBα is an inhibitor of the transcriptional factor NF-κB, and it is an essential component of the signaling pathways that lead to expression of inflammatory molecules. These include cytokines and costimulatory molecules associated with antigen pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cfd5e5c16276311e5c2dc829e8ee734
https://pubmed.ncbi.nlm.nih.gov/19237504
https://pubmed.ncbi.nlm.nih.gov/19237504