Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Bruce T. Liang"'
Autor:
William DeGroat, Habiba Abdelhalim, Elizabeth Peker, Neev Sheth, Rishabh Narayanan, Saman Zeeshan, Bruce T. Liang, Zeeshan Ahmed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Cardiovascular diseases (CVDs) are complex, multifactorial conditions that require personalized assessment and treatment. Advancements in multi-omics technologies, namely RNA sequencing and whole-genome sequencing, have provided translationa
Externí odkaz:
https://doaj.org/article/b57cbcd9db094e298b7798240d408a22
Autor:
Daylin Gamiotea‐Turro, Chunxia G. Cronin, Sanjeev Kumar Yadav, Arun Kumar Yadawa, Mary‐Katherine Cormier, Bruce T. Liang, Rajkumar Verma
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 19 (2024)
Background Purinergic receptor P2X4 (P2X4R), highly expressed on microglia and macrophages, is activated by ATP released from damaged cells and linked to poststroke inflammation. Previous studies showed that short‐term P2X4R inhibition reduces infl
Externí odkaz:
https://doaj.org/article/2c5618adfce648588cc26e89ad39cd06
Autor:
Ishani Mhatre, Habiba Abdelhalim, William Degroat, Shreya Ashok, Bruce T. Liang, Zeeshan Ahmed
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cardiovascular disease (CVD) is caused by a multitude of complex and largely heritable conditions. Identifying key genes and understanding their susceptibility to CVD in the human genome can assist in early diagnosis and personalized treatme
Externí odkaz:
https://doaj.org/article/f4690423893d4a799f5fa44768b4ac4a
Autor:
Matthew Dean, Min Jung Kim, Sharon Dimauro, Susan Tannenbaum, Garth Graham, Bruce T. Liang, Agnes S. Kim
Publikováno v:
Cardio-Oncology, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background Biomarkers represent a potential tool to identify individuals at risk for anthracycline-induced cardiotoxicity (AICT) prior to symptom onset or left ventricular dysfunction. Methods This study examined the levels of cardiac and no
Externí odkaz:
https://doaj.org/article/bd6e18f5f66049bea8385d85a4281718
Autor:
Zeeshan Ahmed, Saman Zeeshan, Nicholas Persaud, William Degroat, Habiba Abdelhalim, Bruce T. Liang
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 3, Pp n/a-n/a (2023)
Abstract Background Cardiovascular disease (CVD) is a leading cause of premature mortality in the United States and the world. CVD comprises several complex and mostly heritable conditions, which range from myocardial infarction to congenital heart d
Externí odkaz:
https://doaj.org/article/91debb155c784f9dbc04829d5c190114
Publikováno v:
Human Genomics, Vol 15, Iss 1, Pp 1-18 (2021)
Abstract Background Heart failure (HF) is one of the most common complications of cardiovascular diseases (CVDs) and among the leading causes of death in the US. Many other CVDs can lead to increased mortality as well. Investigating the genetic epide
Externí odkaz:
https://doaj.org/article/f0149186e0b14a1a9d7c8e309e28bd3d
Autor:
Kevin D. Dieckhaus, Min-Jung Kim, Jian-Bing Shen, Tina S. Liang, Michael J. Kleinberg, Kristen M. Siedlarz, David B. Banach, Mark L. Metersky, Rob P. Fuller, Eric M. Mortensen, Bruce T. Liang
Publikováno v:
Vaccines, Vol 11, Iss 2, p 358 (2023)
Since the emergence of SARS-CoV-2, maintaining healthcare worker (HCW) health and safety has been fundamental to responding to the global pandemic. Vaccination with mRNA-base vaccines targeting SARS-CoV-2 spike protein has emerged as a key strategy i
Externí odkaz:
https://doaj.org/article/eb538d69a54d440c8729eb13ef51cc37
Publikováno v:
Clinical and Translational Medicine, Vol 8, Iss 1, Pp 1-11 (2019)
Abstract Background The last decade has seen a dramatic increase in the availability of scientific data, where human-related biological databases have grown not only in count but also in volume, posing unprecedented challenges in data storage, proces
Externí odkaz:
https://doaj.org/article/799df428f8f84124bca4b9b93c4dfb10
Autor:
Kiran S, Toti, Rajkumar, Verma, Michael J, McGonnigle, Daylin, Gamiotea Turro, Zhiwei, Wen, Sarah A, Lewicki, Bruce T, Liang, Kenneth A, Jacobson
Publikováno v:
Journal of medicinal chemistry. 65(20)
We analyzed the P2X4 receptor structure-activity relationship of a known antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8887d7389666963c50970a43c68bce6
https://pubmed.ncbi.nlm.nih.gov/36150180
https://pubmed.ncbi.nlm.nih.gov/36150180
Autor:
Olga H. Toro-Salazar, Ji Hyun Lee, Kia N. Zellars, Paige E. Perreault, Kathryn C. Mason, Zhu Wang, Kan N. Hor, Eileen Gillan, Caroline J. Zeiss, Daniel M. Gatti, Brooke T. Davey, Shelby Kutty, Bruce T. Liang, Francis G. Spinale
Publikováno v:
Cardio-Oncology, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Anthracycline induced cardiomyopathy is a major cause of mortality and morbidity among pediatric cancer survivors. It has been postulated that oxidative stress induction and inflammation may play a role in the pathogenesis of this
Externí odkaz:
https://doaj.org/article/81eee6c0ac974fc38f9cb55f49d53ef9