Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Bruce T. Hope"'
Autor:
James I. Matchynski, Timothy S. Cilley, Nareen Sadik, Kassem M. Makki, Min Wu, Rayyan Manwar, Alexander R. Woznicki, Srinivasu Kallakuri, Cynthia L. Arfken, Bruce T. Hope, Kamran Avanaki, Alana C. Conti, Shane A. Perrine
Publikováno v:
Photoacoustics, Vol 33, Iss , Pp 100551- (2023)
Understanding the neurobiology of complex behaviors requires measurement of activity in the discrete population of active neurons, neuronal ensembles, which control the behavior. Conventional neuroimaging techniques ineffectively measure neuronal ens
Externí odkaz:
https://doaj.org/article/d280b5e952bc4c328a4279584a7a8c1e
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/b65db4df7a8248ff89078429406cd2f3
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/fc34f775fa9d4b29990347d6cd8e84a8
Autor:
James I. Matchynski, Rayyan Manwar, Karl J. Kratkiewicz, Rajtarun Madangopal, Veronica A. Lennon, Kassem M. Makki, Abbey L. Reppen, Alexander R. Woznicki, Bruce T. Hope, Shane A. Perrine, Alana C. Conti, Kamran Avanaki
Publikováno v:
Photoacoustics, Vol 24, Iss , Pp 100297- (2021)
Measuring neuroactivity underlying complex behaviors facilitates understanding the microcircuitry that supports these behaviors. We have developed a functional and molecular photoacoustic tomography (F/M-PAT) system which allows direct imaging of Fos
Externí odkaz:
https://doaj.org/article/849d98a1f58a436b92be66f7d30b5476
Autor:
Amanda Laque, Genna L. De Ness, Grant E. Wagner, Hermina Nedelescu, Ayla Carroll, Debbie Watry, Tony M. Kerr, Eisuke Koya, Bruce T. Hope, Friedbert Weiss, Greg I. Elmer, Nobuyoshi Suto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use b
Externí odkaz:
https://doaj.org/article/32e54db896614f8fb088a7ce1dccb649
Autor:
Benjamien Moeyaert, Graham Holt, Rajtarun Madangopal, Alberto Perez-Alvarez, Brenna C. Fearey, Nicholas F. Trojanowski, Julia Ledderose, Timothy A. Zolnik, Aniruddha Das, Davina Patel, Timothy A. Brown, Robert N. S. Sachdev, Britta J. Eickholt, Matthew E. Larkum, Gina G. Turrigiano, Hod Dana, Christine E. Gee, Thomas G. Oertner, Bruce T. Hope, Eric R. Schreiter
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Methods to directly label active neurons are still lacking. Here the authors develop CaMPARI2, a photoconvertible fluorescent protein sensor for neuronal activity with improved brightness and calcium binding kinetics, as well as an antibody to amplif
Externí odkaz:
https://doaj.org/article/0bc2383719ed4d3a919e09c4acecd7ca
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2017)
Many learned behaviors are directed by complex sets of highly specific stimuli or cues. The neural mechanisms mediating learned associations in these behaviors must be capable of storing complex cue information and distinguishing among different lear
Externí odkaz:
https://doaj.org/article/4c672692ec264510878388776e5561c1
Autor:
Sarah M. Claypool, David J. Reiner, Sana Behdin, Javier Orihuel, Ashley Batista, Kiera E. Caldwell, Jonathan J. Chow, Jennifer M. Bossert, F. Javier Rubio, Bruce T. Hope, Yavin Shaham
Publikováno v:
The Journal of Neuroscience. 43:2597-2614
We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after food choice-induced voluntary abstinence. Here, we used this model to further study the role of Pir and its afferent projections in fentanyl relapse. We t
Autor:
Rajtarun Madangopal, Eric R. Szelenyi, Joseph Nguyen, Megan B. Brenner, Olivia R. Drake, Diana Q. Pham, Aniruddha Shekara, Michelle Jin, Jia Jie Choong, Conor Heins, Lauren E. Komer, Sophia J. Weber, Bruce T. Hope, Yavin Shaham, Sam A. Golden
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(45)
Studies using rodent models have shown that relapse to drug or food seeking increases progressively during abstinence, a phenomenon termed ‘incubation of craving’. Mechanistic studies of incubation of craving have focused on specific neurobiologi
Autor:
Rajtarun Madangopal, Brendan J Tunstall, Lauren E Komer, Sophia J Weber, Jennifer K Hoots, Veronica A Lennon, Jennifer M Bossert, David H Epstein, Yavin Shaham, Bruce T Hope
Publikováno v:
eLife, Vol 8 (2019)
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help develop treatments to prevent relapse, but these models have ubiquitously
Externí odkaz:
https://doaj.org/article/dd1c5cdadf0c42d6a522a5193016f968