Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Bruce S. Jacobson"'
Autor:
Bruce S. Jacobson, Honor L. Glenn
Publikováno v:
Cell Motility and the Cytoskeleton. 55:265-277
The adhesion of a cell to its surrounding matrix is a key determinant in many aspects of cell behavior. Adhesion consists of distinct stages : attachment, cell spreading, motility, and/or immobilization. Interrelated signaling pathways regulate these
Autor:
Bruce S. Jacobson
Publikováno v:
The American Journal of Pathology. 156:737-742
Endothelial cell migration, replication, and vessel formation are functions generally considered to make up the initial phase of angiogenesis. Angiogenesis can also be considered to have a major second phase when small vessels enlarge by expansion an
Publikováno v:
The Journal of Cell Biology
By using an immunoisolation procedure (Stan, R.-V., W.G. Roberts, K. Ihida, D. Predescu, L. Saucan, L. Ghitescu, and G.E. Palade. 1997. Mol. Biol. Cell. 8:595–605) developed in our laboratory, we have isolated a caveolar subfraction from rat lung e
Publikováno v:
Endothelium. 6:241-250
A monoclonal antibody raised against purified rat lung endothelial plasma membranes was found to recognize an apparently novel, 85 kD, integral endothelial plasma membrane glycoprotein. By immunofluorescence and electron microscope immunocytochemistr
Autor:
John R. Crawford, Bruce S. Jacobson
Publikováno v:
Molecular Biology of the Cell. 9:3429-3443
Attachment of HeLa cells to gelatin induces the release of arachidonic acid (AA), which is essential for cell spreading. HeLa cells spreading in the presence of extracellular Ca2+released more AA and formed more distinctive lamellipodia and filopodia
Publikováno v:
Journal of Cellular Physiology. 173:361-370
HeLa cell spreading on a gelatin substrate requires the activation of protein kinase C (PKC), which occurs as a result of cell-attachment-induced activation of phospholipase A2 (PLA2) to produce arachidonic acid (AA) and metabolism of AA by lipoxygin
Autor:
Bruce S. Jacobson, K L Auer
Publikováno v:
Molecular Biology of the Cell. 6:1305-1313
Clustering of integrin receptors during cell adhesion stimulates signal transduction across the cell membrane. Second messengers are generated, activating cytosolic proteins and causing cytoskeletal assembly and rearrangement. HeLa cell adhesion to a
Autor:
Jang-Soo Chun, Bruce S. Jacobson
Publikováno v:
Molecular Biology of the Cell. 4:271-281
Release of arachidonic acid (AA) and subsequent formation of a lipoxygenase (LOX) metabolite(s) is an obligatory signal to induce spreading of HeLa cells on a gelatin substratum (Chun and Jacobson, 1992). This study characterizes signaling pathways t
Autor:
D.B. Stolz, Bruce S. Jacobson
Publikováno v:
Journal of Cell Science. 103:39-51
In this report we describe a rapid, high-yield protocol for the isolation of apical (AP) and basolateral (BL) plasma membrane domains from monolayers of bovine aortic endothelial cells (BAECs) grown on tissue culture dishes as well as microcarrier be
Publikováno v:
Journal of Cell Science. 103:53-68
This project examines the transcellular membrane protein polarity of bovine aortic endothelial cell (BAEC) monolayers in vitro with respect to the roles that intercellular junctions (as defined by comparing confluent and subconfluent monolayers) and