Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Bruce R. Stevenson"'
Publikováno v:
Molecular Biology of the Cell. 14:1757-1768
We previously demonstrated that exogenous expression of a truncated form of the tight junction protein ZO-3 affected junctional complex assembly and function. Current results indicate that this ZO-3 construct influences actin cytoskeleton dynamics mo
Publikováno v:
Pharmaceutical Research. 18:316-322
Purpose. To demonstrate utility of folic acid-coated liposomes for enhancing the delivery of a poorly absorbed glycopeptide, vancomycin, via the oral route.
Publikováno v:
The Journal of Cell Biology
The functional characteristics of the tight junction protein ZO-3 were explored through exogenous expression of mutant protein constructs in MDCK cells. Expression of the amino-terminal, PSD95/dlg/ZO-1 domain-containing half of the molecule (NZO-3) d
Publikováno v:
Journal of Biological Chemistry. 274:35179-35185
Defining how the molecular constituents of the tight junction interact is a prerequisite to understanding tight junction physiology. We utilized in vitro binding assays with purified recombinant proteins and immunoprecipitation analyses to define int
Publikováno v:
Journal of Controlled Release. 60:189-198
The design of targeted oral liposomes is anticipated to improve the systemic delivery of poorly absorbed agents, such as proteins and peptides. A poly(ethylene oxide) (PEO)-folic acid (FA) derivative was prepared and evaluated for improving liposome
Publikováno v:
The Journal of Cell Biology
A 130-kD protein that coimmunoprecipitates with the tight junction protein ZO-1 was bulk purified from Madin-Darby canine kidney (MDCK) cells and subjected to partial endopeptidase digestion and amino acid sequencing. A resulting 19–amino acid sequ
Publikováno v:
Experimental Cell Research. 218:540-550
Vectorial transport in the thyroid epithelium requires an efficient barrier against passive paracellular flux, a role which is principally performed by the tight junction (zonula occludens). There is increasing evidence that tight junction integrity
Publikováno v:
American Journal of Physiology-Cell Physiology. 262:C461-C469
ZO-1 is a high molecular mass phosphoprotein peripherally associated with the cytoplasmic surface of tight junctions in epithelial and endothelial cells. We report here that ZO-1 is also present in several nonepithelial cell types in vitro that are n
Autor:
Brigitte H. Keon, Bruce R. Stevenson
Publikováno v:
Annual review of cell and developmental biology. 14
▪ Abstract The tight junction forms a regulated barrier in the paracellular pathway between epithelial and endothelial cells. This intercellular junction also demarcates the compositionally distinct apical and basolateral membranes. While the exist
Publikováno v:
The Journal of membrane biology. 163(3)