Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bruce R. Ito"'
Autor:
Ricardo A. García, PhD, Bruce R. Ito, PhD, John A. Lupisella, MSc, Nancy A. Carson, BSc, Mei-Yin Hsu, MSc, Gayani Fernando, MSc, Madeleine Heroux, PhD, Michel Bouvier, PhD, Elizabeth Dierks, PhD, Ellen K. Kick, PhD, David A. Gordon, PhD, Jian Chen, PhD, Gabe Mintier, BSc, Marilyn Carrier, PhD, Stéphane St-Onge, MSc, Himanshu Shah, MSc, Jordan Towne, BSc, Marcela Sotelo Bucardo, BSc, Xiuying Ma, PhD, Carol S. Ryan, BSc, Nicholas R. Wurtz, PhD, Jacek Ostrowski, PhD, Francisco J. Villarreal, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 905-920 (2019)
Summary: Dysregulated inflammation following myocardial infarction (MI) promotes left ventricular (LV) remodeling and loss of function. Targeting inflammation resolution by activating formyl peptide receptors (FPRs) may limit adverse remodeling and p
Externí odkaz:
https://doaj.org/article/87187fce26ae464386af76218484bf38
Autor:
Francisco Villarreal, Israel Ramirez-Sanchez, Moises Muratt Bustamante-Pozo, Marcos Ayala, Jeffrey H. Omens, Maria L Loredo-Mendoza, Viridiana Navarrete, Guillermo Ceballos, Bruce R. Ito, Alejandra Garate-Carrillo
Publikováno v:
Exp Biol Med (Maywood)
We previously reported on the development of left ventricular (LV) structural and functional changes in an aged, female rat model where the effects of ovariectomy and excess weight (stimulated by fructose in water) were also explored. Ovariectomy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac1cd46952a68076fbc7976eae5691c
https://doi.org/10.1177/1535370220912699
https://doi.org/10.1177/1535370220912699
Autor:
Stéphane St-Onge, Bruce R. Ito, John A. Lupisella, Madeleine Héroux, Ricardo Garcia, Marilyn Carrier, Mei-Yin Hsu, Carol S. Ryan, Michel Bouvier, Elizabeth A. Dierks, Nicholas R. Wurtz, Ellen K. Kick, Jian Chen, Nancy A. Carson, Gayani Fernando, Jordan Kelly Towne, Jacek Ostrowski, Francisco Villarreal, Himanshu Shah, Xiuying Ma, Marcela Sotelo Bucardo, Gabe Mintier, David A. Gordon
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 905-920 (2019)
Summary: Dysregulated inflammation following myocardial infarction (MI) promotes left ventricular (LV) remodeling and loss of function. Targeting inflammation resolution by activating formyl peptide receptors (FPRs) may limit adverse remodeling and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c03af88d759da1d54a687d698b9a270
http://www.sciencedirect.com/science/article/pii/S2452302X19301962
http://www.sciencedirect.com/science/article/pii/S2452302X19301962
Autor:
Bruce R. Ito, Jeffrey H. Omens, Israel Ramirez-Sanchez, Moises Bustamante, Nancy L. Carson, Ricardo Garcia, Guillermo Ceballos, Francisco Villarreal, Alejandra Garate-Carrillo
Publikováno v:
The Journal of Physiology. 597:1805-1817
KEY POINTS Heart failure with preserved ejection fraction (HFpEF) is seen more frequently in older women; risk factors include age, hypertension and excess weight. No female animal models of early stage remodelling (pre-HFpEF) have examined the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05f5dcd09e9891ed4066b9d4c656306
https://doi.org/10.1113/jp277479
https://doi.org/10.1113/jp277479
Autor:
Moises Muratt Bustamante-Pozo, Rongan Zhang, Nancy L. Carson, Madeleine Héroux, Michel Bouvier, Jian Chen, David A. Gordon, Bruce R. Ito, Stéphane St.-Onge, Gayani Fernando, Marilyn Carrier, Francisco Villarreal, Zhaoqing Wang, Alejandra Garate-Carrillo, Carol S. Ryan, Jignesh Nagar, Jacek Ostrowski, John A. Lupisella, Ricardo Garcia, Shailesh Dudhgaonkar, Debra Search, Ellen K. Kick, Xiuying Ma, Ruth R. Wexler, Mei-Yin Hsu, Elizabeth A. Dierks, Nicholas R. Wurtz, John Allocco
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e8893e04bab7931d672cda68a46242
https://pubmed.ncbi.nlm.nih.gov/34466754
https://pubmed.ncbi.nlm.nih.gov/34466754
Autor:
John A. Lupisella, Kiyoshi Fujii, David A. Gordon, Mei-Yin Hsu, Toshikazu Yamaoka, Yasuchi Kohno, Kohei Ohata, Kosuke Tsuda, Kazuto Arakawa, Nancy L. Carson, Kazunori Fukuchi, Ruth R. Wexler, Francisco Villarreal, Ellen K. Kick, Junichi Ishiyama, Jacek Ostrowski, Shingo Matsushima, Hitomi Yamada, Yoshifumi Saito, Bruce R. Ito, Yoshikazu Asahina, Ricardo Garcia, Nicholas R. Wurtz
Publikováno v:
Journal of medicinal chemistry. 63(17)
Formyl peptide receptor 2 (FPR2) agonists can stimulate resolution of inflammation and may have utility for treatment of diseases caused by chronic inflammation, including heart failure. We report the discovery of a potent and selective FPR2 agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae320f52a2002341eb02a49f914b8d9d
https://pubmed.ncbi.nlm.nih.gov/32407089
https://pubmed.ncbi.nlm.nih.gov/32407089
Autor:
Rongan Zhang, Gayani Fernando, Francisco Villarreal, Bruce R. Ito, Elizabeth A. Dierks, Nicholas R. Wurtz, Mei-Yin Hsu, Ricardo Garcia, John A. Lupisella, Y Kohno, Jacek Ostrowski, Carol S. Ryan, Nancy L. Carson, Zhaoqing Wang, Y Asahina
Publikováno v:
European Heart Journal. 40
Background/Introduction Dysregulated inflammation following myocardial infarction (MI) can lead to maladaptive infarct healing, myocardial damage and heart failure. Formyl peptide receptor 2 (FPR2) plays an important role in the ligand-dependent regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b688371cb14bd43dc42231a3265732e
https://doi.org/10.1093/eurheartj/ehz748.0168
https://doi.org/10.1093/eurheartj/ehz748.0168
Autor:
Jeffrey H. Omens, Ricardo Garcia, Guillermo Ceballos, Francisco Villarreal, Israel Ramirez-Sanchez, Moises Muratt Bustamante Pozo, Nancy L. Carson, Bruce R. Ito, Alejandra Garate Carrillo
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b162ef82e24989ce103db6cbc7d688
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb506
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb506
Publikováno v:
Journal of Cardiovascular Electrophysiology. 27:1102-1109
BACKGROUND Biventricular epicardial (Epi) pacing can augment left ventricular (LV) function in heart failure. We postulated that these effects might involve catecholamine release from local autonomic nerve activation. To evaluate this hypothesis we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4c54cf2e88dce7631e7c5ea7f7791f2
https://doi.org/10.1111/jce.13027
https://doi.org/10.1111/jce.13027
Autor:
Moises Muratt Bustamante-Pozo, Guillermo Ceballos, Alejandra Garate-Carrillo, Bruce R. Ito, Francisco Villarreal, Israel Ramirez-Sanchez
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa1febd2cadecf1b5ec0ea84c506087
https://doi.org/10.1096/fasebj.2020.34.s1.09956
https://doi.org/10.1096/fasebj.2020.34.s1.09956